The work to end ALS takes all of us. 💙 Thank you to our researchers, staff, & Board members who rode, volunteered, cheered, & worked behind the scenes to make this year's Tri-State Trek possible. Special congratulations to our Chairwoman, Lynn Nieto, on completing her 1st Trek!

Join us July 23 at 11 AM ET for our next ALS Town Hall: Introducing PRISM ALS. Learn how this global collaboration is expanding access to diverse patient-derived cell models to help accelerate better treatments for ALS. Register today: als.net/als-town-hal...

"I just wish there was something to cure it. But one day there will be." This Father's Day, meet Logan and Skyler—two young advocates turning love for their dads into action for the ALS community. Read their story: als.net/news/two-you...

Ever wondered what it looks like inside ALS research? A custom GoPro ride through CorD2, our automated screening platform named after Corey Reich, offers a rare look at the technology helping ALS TDI researchers evaluate potential therapies every day.

Join us June 18 at 3 PM ET for an ALS TDI Town Hall featuring David Meissner of Your ALS Guide. Get a first look at the new ALS Research Guide, designed to help people with ALS and families better understand research and participation opportunities. 🔗 als.net/als-town-hall/

Why do certain populations face a higher risk of ALS? Champion Insights is studying elite athletes, veterans, and first responders to better understand how genetics, environment, and lifestyle may influence ALS risk and progression. Watch more: youtube.com/watch?v=crtI...

On Monday, Stuart Chapin began a 3,000+ mile ride across the country in honor of his father, who passed away from ALS. Now through August, he’ll ride from NYC to San Francisco to raise funds for ALS research at ALS TDI. Read his story: als.net/news/going-t...

Step up to the plate for Lou Gehrig Day ⚾ Our limited-edition ALS TDI baseball shirt is available now for $30. Order soon to receive yours before June 2! 🛒 alstdi.88blue.com

ALS research has reached a turning point. ALS TDI is expanding our scientific team and building a new 33,000 sq. ft. lab to test more ideas, move faster, and help advance more potential treatments toward clinical trials. Follow along for updates on this landmark expansion.

Honored to announce Team ALS TDI / Google Co-Scientist received a #LongitudePrizeOnALS Discovery Award! We'll use advanced AI to find new drug targets and move closer to real treatments. @mndassoc.bsky.social @challengeworks.bsky.social Learn more: als.longitudeprize.org

Our Fight ALS Film Fest returns for year 5—kicking off ALS Awareness Month. 5 powerful films + special guests from each story. Sunny of Sunnystrong and Her ALS Story returns as emcee. Learn more & register: als.net/als-film-fest/

ALS research has reached a turning point. More ideas than ever—but too few places can turn them into treatments. To meet this moment, ALS TDI is expanding: doubling our research team and building a new 33,000 sq. ft. lab. youtu.be/-Ey4WlCqhX4?... (1/2)

Read a letter from Zach Zangl, diagnosed with ALS in 2024 and now on the board of the ALS 100, a golf event raising funds for ALS research at ALS TDI: als.net/news/l-i-v-i... Alongside our scientists, team members like Carol are here to help you get involved in the mission.

Join us May 15 (3–4 PM ET) for an ALS Town Hall on Champions Insights. Learn how studying higher-risk groups like athletes, veterans, & first responders could help advance ALS research for everyone. Hosted by ALS TDI, Answer ALS & Augie's Quest. Register: als.net/als-town-hall/

We answer only to the ALS community. That means following the science, being transparent about what we find—and what we don’t—and staying accountable to those who need answers most. Thank you for pushing this work forward.

mRNA therapies could target multiple drivers of ALS—but delivery into the brain remains a major hurdle. ALS TDI is collaborating with Dr. Michael Mitchell (UPenn) to develop lipid nanoparticles (LNPs) to deliver these therapies: als.net/news/mrna-lnp-therapies-for-als/

Behind every experiment is a decision: Will this bring us closer to a treatment for ALS? At ALS TDI, we use four key questions to guide every project we take on—so we can focus on what matters most: real impact for people living with ALS. (1/2)

Every data point tells a story. Every participant moves research forward. Keith is part of the ARC Study—where participants are helping ALS TDI researchers uncover critical insights that could lead to new treatments. Be part of it: als.net/arc

Celebrating 20 years of Shawn Sullivan at ALS TDI. From our drug discovery pipeline to the ARC portal, ARC Data Commons, and many internal systems, Shawn’s work supports nearly every part of the Institute. We’re incredibly grateful for his dedication.

Thank you to our 14 incredible NYC Half Marathon runners who braved the cloudy race day yesterday and ran 13.1 miles for ALS research at ALS TDI, raising $68K+. It’s not too late to support their efforts: fundraise.als.net/donate/nychalf

Pictured here is Val caring for our zebrafish in the lab. Zebrafish models help our scientists study ALS and test new ideas that could lead to treatments. We take great care of every animal in our labs, and Val is the zebrafish’s most dedicated caretaker.

Join our ALS TDI Town Hall to explore The Les Turner ALS Foundation’s My ALS Decision Tool™ and ALS TDI’s ALS Trial Navigator — empowering informed decisions about clinical trials. 🗓 March 12, 3–4 PM EST Register: als.net/als-town-hall/

Finding ALS trials shouldn’t be overwhelming. The updated ALS Trial Navigator now features: ✔ Simplified experience ✔ Provider Quick Start ✔ NEALS-affiliated filter Learn more: als.net/news/the-als...

Today is National Caregivers Day. To the extraordinary caregivers in the ALS community, thank you. Your strength and resilience fuel our urgency and push our research forward. We see you. We honor you.

Champion Insights is open. The enrollment portal is live at championinsights.org. At-home ALS research for high-risk/high-performance populations (endurance athletes, military, and first responders). If you know someone who is eligible, please share. #ALS #endALS

We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator. People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website. More updates coming in February!

Science can be powerful—and breathtaking. Congrats to Swetha Gurumurthy, Associate Scientist II, named runner-up in the Royal Society Publishing Photography Competition for her image of iPSC-derived motor neurons studying ALS. Read more here: als.net/news/als-tdi...

🏀 Game on for a cause! This February, Hoops 4 ALS is bringing the heat with 4 Games you won’t want to miss. Tune in or join us in person to cheer on the teams and help support ALS research. Let’s make every point count!

We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator. People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website. More updates coming in February!

You rode. You ran. You danced. You sold. You played. You hosted. You even raised a glass! And together, events hosted by YOU raised $3.5 million for ALS research at ALS TDI in 2025. We are endlessly grateful—and can’t wait to see where 2026 takes us. 💜

Beat the cold in style ❄️ Our new 'END ALS' winter beanies are here! Be sure to grab one while they last and help fuel ALS research. Get yours today: alstdi.88blue.com

What started as a family love of running became a mission to #EndALS. Connor McCullum ran the 2025 NYC Marathon for his dad after an ALS diagnosis—raising nearly $17K for research along the way. Read the full story: als.net/news/connor-...

As we enter a new year, it’s time to take stock—not celebrate. Progress in ALS research happens quietly, over time, because people invest before certainty. In 2026, ALS TDI is focused on growth, acceleration, and urgency with rigor. Read more → als.net/news/on-prog...

AP-101 just advanced toward Phase 3 trials—and ALS TDI helped make it possible. Years ago, donor support funded the unglamorous preclinical work behind this moment. That’s the power of flexible research funding. Read more: www.als.net/news/a-story...

What does it mean to be a nonprofit biotech? At ALS TDI, it means inventing and advancing new medicines in our own lab—accountable only to the ALS community. Every dollar goes back into urgent, open ALS research. Your support fuels the science. Donate: als.net/endals2025/?...

Happy holidays from all of us at ALS TDI. We’re deeply grateful for our community of supporters, scientists, and advocates who make our work possible. Wishing you a season filled with comfort, connection, and time with those you love.

LIMITED BIBS LEFT! Run for ALS research in: 🇫🇷 Hoka Semi de Paris 🇫🇷 Schneider Electric Marathon de Paris 🇦🇺 TCS Sydney Marathon Apply NOW to join Team ALS TDI and make every mile count! als.net/news/2026-ma...

Emily is feeling inspired after an energizing four days at the 2025 Alliance Meeting & Allied Professionals Forum in San Diego, CA!

ARC’s in-home blood collection program is powering ALS discoveries — from genomics to biomarker research to global data sharing. 🧬 See how each blood draw accelerates progress at ALS TDI and beyond. Read the full blog: als.net/news/how-blo...

Every discovery brings us one step closer to treatments, and ultimately, an end to ALS. Our team is dedicated to understanding what causes ALS, so no one faces this disease without answers.

Team ALS TDI applications are OPEN for two new 2026 race opportunities! 🏃‍♂️💙 🇺🇸 United Airlines NYC Half — Mar 15, 2026 Apply: fundraise.als.net/marathon/nyc... 🇦🇺 TCS Sydney Marathon — Aug 30, 2026 Apply: sm26.grassrootz.com/the-als-ther... 🔔 Deadline: Dec 5, 2025

The Yozwiak family continues Chris’s legacy with relentless love and action. 💜 Support their mission to help end ALS and fund life-saving research: als.net/news/EOY-202...

Our 2025 Tribute Wall stands as a powerful reminder of the incredible community we are fighting for. If you’d like to honor someone on our Tribute Wall, you can make a contribution of any size: als.net/2025-tribute.... Thank you for supporting our mission.

Science is taking over our lab! 🧪 Help us make room for research, use code GIVETHANKS25 for 25% off remaining merch while supplies last. We’re moving to a new online store soon, so grab your favorites before they’re gone: fundraise.als.net/store

Compassion drives our work at ALS TDI. Danielle Boyce, our Principal Investigator of Real World Evidence, embodies that; advancing rigorous ALS research while honoring the people behind the data. Thank you, Danielle, for your impact and leadership!

🚨 Applications to run with Team ALS TDI in Paris & Big Sur close TODAY, Nov 10! Join us, run in amazing marathons, and help #ENDALS. Learn more and apply today: als.net/news/2026-ma...

At the 2025 ALS TDI Summit, our CEO and CSO Dr. Fernando Vieira opened with a powerful message on breakthroughs in ALS research and hope for the future. Watch his talk, and all Summit presentations, anytime at youtube.com/ALSTDI.

💜 November is National Family Caregivers Month, a time to honor those who give so much of themselves to care for others. At ALS TDI, we recognize the vital role caregivers play in every ALS journey. We see you, we appreciate you, and we thank you for your love and dedication.

Thank you to everyone who joined us at our Open House in Watertown! 💙 We loved showing you our lab, reconnecting with the community, and sharing some Ales for ALS brews 🍻 Check out all the photos here: facebook.com/share/p/1CcB...

Thank you to everyone who joined us for our 14th Annual White Coat Affair Gala last Saturday in Boston! 💜 We were so honored to spend an evening full of smiles, dancing, and community with you. Stay tuned for the full photo album from the night! ✨