New research has found that omega-3 fatty acids may not be as effective in the treatment of brain injuries and Alzheimer’s. https://www.discovermagazine.com/do-omega-3s-really-protect-the-brain-the-answer-may-depend-on-your-health-49067

A new study links accelerated biological aging and the global rise in early-onset cancers. I would be interested to see similar research into early-onset dementia. https://medicine.washu.edu/news/faster-aging-in-younger-generations-linked-to-rise-in-early-onset-cancer/

Join Drs. Dale Bredesen, Hans Frykman, & Chris Coward for a discussion on how BrainScan, Apollo Health's blood biomarker panel featuring high-sensitivity p-Tau 217, can detect cognitive decline earlier and support personalized care. https://us02web.zoom.us/webinar/register/WN_-VnlhEgORTela5fzBroxbw

The American Heart Association recently released a statement outlining 10 familiar factors that adversely affect brain health. https://www.medicalnewstoday.com/articles/brain-health-shaped-by-8-lifetime-mental-physical-environmental-and-lifestyle-factors

Workout warriors rejoice! New research shows that flexing your abs can help clean your brain. https://scitechdaily.com/this-simple-movement-could-be-secretly-cleaning-your-brain/

Congratulations to Dr. Ram Rao, Julie Gregory, and the whole team on the publication of a superb perspective on the KetoFLEX 12/3 diet and its remarkable impact on cognition. For anyone interested in why this nutritional approach works so well: https://www.mdpi.com/2072-6643/18/13/2206

New research from Florida Atlantic University found underlying mitochondrial disruptions that occur in both dementia and obesity, potentially explaining their connection. https://www.news-medical.net/news/20260505/Obesity-and-Alzheimere28099s-linked-through-early-metabolic-disruptions.aspx

In new research, nitrate-rich vegetables decreased dementia risk, while nitrates from processed meat or even drinking water increased it. Vegetables’ antioxidants may turn nitrate into beneficial nitric oxide, not N-nitrosamines. https://www.sciencedaily.com/releases/2026/06/260606075852.htm

increasing Sox9 protein levels in mice energized their aging astrocytes, preserving cognitive function and improving amyloid and tau clearance. Amyloid and tau plaques are symptoms not causes, but clearing them may still provide benefit. https://www.sciencedaily.com/releases/2026/05/260502013550.htm

A case study on psilocybin has made waves recently as a result of the impact it had on an 80-year-old Alzheimer’s patient. The paper describes miraculous recovery of bladder control, speech, and ambulation. https://medicalxpress.com/news/2026-06-high-dose-psilocybin-temporarily-lost.html

The Ageless Brain was selected for the Amazon Prime Day book sale. Let’s all stay sharp to 100—take advantage of the Amazon sale, get a copy of The Ageless Brain, and enhance your brainspan. https://www.amazon.com/Ageless-Brain-Sharpen-Protect-Lifetime/dp/1250362598

According to a new meta-analysis of over 1.25 million people, single falls were associated with a 20% increased risk of dementia, while recurrent falls saw an increase of 74%. https://www.independent.co.uk/news/science/dementia-early-symptom-age-fall-b2971960.html

Researchers have found that anyone, regardless of age, can improve their brain performance through continued, targeted practice. You’re never too old to learn something new. https://medicalxpress.com/news/2026-05-inevitability-cognitive-decline-brain-gain.html

Strength Training, already a recommendation of the Bredesen Protocol, was found in new research to reduce the risk of death from neurological and cardiovascular disease, with just 2 hours per week being enough for a profound effect. https://www.bbc.com/news/articles/c0r2lekenlpo

Gardening projects are becoming a popular intervention for those with dementia and other neurodegenerative diseases. Socialization, exercise, stress relief, and time outdoors are all brain-building activities. https://www.ft.com/content/e75135d4-4649-41ff-987c-1c8865c8f6e2?syn-25a6b1a6=1

The cheap amino acid Arginine was found to be an effective treatment in animal models of Alzheimer’s. The compound's ability to reduce pro-inflammatory cytokine gene activity is a noteworthy finding here. https://www.sciencedaily.com/releases/2026/05/260504075512.htm

Recent research showing the roots of dementia can trace back to childhood aligns perfectly with what we’ve said for years. One key to optimizing outcomes is starting prevention early. https://www.sciencealert.com/the-roots-of-dementia-trace-back-all-the-way-to-childhood-experts-reveal

A 30-minute sauna session with a cold shower in the middle can increase your white blood cell count. This response mirrors the boost you see following physical activity or stress. https://scitechdaily.com/saunas-may-do-more-than-raise-body-temperature-they-activate-your-immune-system/

A new study from our partners at Vielight adds more evidence that photobiomodulation (PBM) can be used as a tool against neurodegenerative diseases. This time, they found evidence that PBM could modulate cerebrospinal fluid flow. https://www.brainstimjrnl.com/article/S1935-861X(25)00390-0/fulltext

Congratulations to Kerry Rutland, Dr. Neil Nathan, and Dr. Chi Kim on their landmark publication documenting the first example of reversal of cognitive decline in PCA (posterior cortical atrophy). https://www.mdpi.com/2673-8937/6/2/20

Movement is a pillar of the ReCODE Protocol for protecting your brain health. A sedentary lifestyle reduces blood flow to the brain, contributes to poor heart health, reduces neuroplasticity, and more. https://www.eatingwell.com/experts-warn-this-habit-could-age-your-brain-fast-11943350

You already know that candy is bad for brain health, but a new study will have you asking if that’s because of the sugar or the… arsenic. 28 popular candies were found to have “toxic levels of arsenic” in a recent test. https://www.southernliving.com/arsenic-in-candy-11900535

According to a new longitudinal study, higher tau burden levels cause faster cognitive decline in women than in men. However, both men and women should know their p-tau 217 levels if they are over 35.

There’s plenty of evidence to show that Type 2 diabetes can increase your risk of dementia, and some data suggesting similar findings for Type 1. But, there is much more to it. https://www.uchealth.org/today/diabetes-increases-risk-of-alzheimers-disease/

One dose of a stem cell treatment derived from donated bone marrow was enough to significantly improve seniors' physical endurance 9 months later. https://www.sciencefocus.com/news/stem-cell-reverse-frailty

Tanycytes are little-known brain cells that may influence Alzheimer’s progression by helping clear tau proteins. While clearing plaques from the brain has not yet provided a breakthrough, clearance likely plays a role in progression. https://www.sciencedaily.com/releases/2026/03/260307155945.htm

Good news for our coffee and tea drinkers: 2-3 cups of caffeinated coffee can reduce your risk of dementia by 18%. Higher tea consumption saw similar results, but decaf coffee did not. https://news.harvard.edu/gazette/story/2026/02/drinking-2-3-cups-of-coffee-a-day-tied-to-lower-dementia-risk/

The Assistance League of Los Angeles helps thousands of children in need, and I was honored to speak to their College Alumni Auxiliary, led by June Bilgore, about brain health this week.

Crank up the radio! Frequently playing, or even listening to, music may act like a “full brain workout” and have a potent neuroprotective benefit, according to new research. https://www.huffpost.com/entry/listening-to-music-every-day-lower-dementia-risk-goog_l_69a07bc4e4b078861704a925

A new study shows that air pollution may directly cause Alzheimer’s, as we’ve said… for a decade! https://theconversation.com/air-pollution-may-directly-contribute-to-alzheimers-disease-new-study-275873

Dark chocolate is a KetoFLEX 12/3 approved treat, and new research adds to the reasons. Theobromine, a compound found in cocoa, may help slow biological aging! However, cadmium and lead can be serious concerns. https://www.foodandwine.com/theobromine-in-dark-chocolate-linked-to-slower-aging-11887830

Drinking water from newer carbonate aquifers increases your Parkinson’s risk 62 percent compared to water from older glacial aquifers, potentially because of pollution. https://www.newsweek.com/one-type-of-drinking-water-linked-to-up-to-62-higher-parkinsons-risk-11603834

Consuming a plant-forward diet can support gut health, reduce inflammation, and protect cells from oxidative stress, & new research shows it increases your likelihood of reaching 70 without ailments. https://www.prevention.com/food-nutrition/healthy-eating/a70009416/best-healthy-aging-diet-study/

Red light therapy has been on the rise in recent years, and with good reason. Research found that football players who used red light therapy prevented brain inflammation. https://healthcare.utah.edu/newsroom/news/2026/01/medical-grade-near-infrared-light-therapy-specific-frequencies-shows-promise

People with more protein in their urine had a significantly greater risk of developing dementia, according to new research. Why? The same blood vessel damage that causes high-protein urine is likely harming the brain. https://beingpatient.com/urine-test-dementia-risk/

How Epstein-Barr is linked to Multiple Sclerosis has been a mystery. New research suggests that cross-reactive T cells targeting the brain protein Anoctamin-2 (ANO2) may be the culprit. https://www.clinicallab.com/new-mechanism-links-epstein-barr-virus-to-multiple-sclerosis-28526

A common bacterium that causes pneumonia and sinus infections can linger in the eye and brain for years, creating inflammation and possibly causing Alzheimer's, according to a new study. https://www.newswise.com/articles/common-bacteria-discovered-in-the-eye-linked-to-cognitive-decline

The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two years. https://sciencedaily.com/releases/2026/01/260128075359.htm

Those consuming more preservatives were more likely to develop several cancers and type 2 diabetes. The most significant link was between sodium nitrate, commonly used in cured meats, and prostate cancer. https://www.foodandwine.com/food-preservatives-linked-to-cancer-diabetes-new-study-11890398

As you might well imagine, the brains of those getting around 150 minutes of weekly moderate-to-vigorous exercise appeared biologically younger in MRI scans in new research. https://www.sciencealert.com/exercise-can-actually-make-your-brain-look-younger-mri-scans-reveal

Obesity and high blood pressure can directly cause dementia, not just increase the risk, according to new research. Higher body weight, particularly when it led to elevated blood pressure, actually harmed brain health. https://sciencedaily.com/releases/2026/01/260126231847.htm

Alzheimer's disease blood biomarkers rose much more quickly in obese individuals, showing obesity is a modifiable risk, according to research from our colleague Cyrus Raji. https://sciencedaily.com/releases/2025/12/251210092019.htm

The Randomized Control Trial isn’t just the most successful Alzheimer’s trial ever, it’s a building block for even more future success. Read more about what’s ahead in my new blog for Apollo Health. https://www.apollohealthco.com/archimedes-alzheimer-and-trials-a-place-to-stand/

Even after years of warnings, millions with dementia are still prescribed drugs linked to falls and confusion. Do not wait for the medical establishment to catch up to the science—take steps now to prevent and reverse cognitive decline. https://sciencedaily.com/releases/2026/01/260113220915.htm

On January 23rd at 2pm PT, Dr. Craig Tanio, one of the key trial investigators, will describe enhancements to the ReCODE protocol. To register for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_-ROlIql_QtqcawMw_bIEhw#/registration

Arginine can help reduce the risk of tooth decay, shifts the oral microbiome, and reduces acid formation in the mouth. Given the mouth-brain connection, could an arginine oral rinse be neuroprotective? https://scitechdaily.com/goodbye-cavities-this-natural-amino-acid-helps-teeth-fight-sugar/

This is an important chart from our recent preprint of the Evanthea trial, which was based on ReCODE. You don’t need to accept the standard of care or settle for a reduced rate of decline - it is possible to reverse the symptoms of Alzheimer’s: https://www.apollohealthco.com/evanthea-trial/

The Evanthea randomized clinical trial has concluded, and the cognitive improvements exceed anything previously published. Join Dr. Bredesen on Friday, January 9th at 2 PM PT to discuss: https://us02web.zoom.us/webinar/register/WN_dMG3GyFlSLigtQoSanuUQA#/registration

Your body’s natural cleaning crew, mononuclear phagocytes, do less cleaning as they age. By developing “young” phagocytes using stem cells, researchers improved memory and created healthier microglia in mice. https://www.sciencealert.com/young-immune-cells-partly-reverse-alzheimers-symptoms-in-mice

Happy New Year to all, and I hope that everyone is enjoying time with loved ones. Meanwhile, we have very exciting results from our randomized controlled trial, and these have just been posted as a preprint: https://www.preprints.org/frontend/manuscript/8118568f183e2ba91ec2a1d3b3d08fb9/download_pub