A new device is helping those with advanced age-related macular degeneration see again, and likely provides cognitive protection by supporting brain stimulation. https://www.nbcnews.com/health/health-news/tiny-eye-implant-special-glasses-legally-blind-patients-can-read-rcna238488

Live from Palm Springs at the California Assisted Living Association Conference! 🌴 Discussing how The Vineyards translates our research into real-life programs for their residents. Learn more about our partnership here: https://lifeatthevineyards.org/cognitive-care

Join Dr. Dale Bredesen and Judy Benjamin this Tuesday, October 28th at 3:00pm PT / 6:00pm ET as we go LIVE to talk about the final stretch of her historic walk across America. To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ

Flavanols, found in green tea, berries, broccoli, and other foods, have long been found to reduce cardiovascular disease risk. Now, a study shows flavanol-rich supplements reduced age-related inflammation, likely promoting cognitive health as well. https://doi.org/10.1093/ageing/afaf269

99% of heart attacks and strokes were preceded by at least one of just four risk factors. Unsurprisingly, they are all also connected with cognitive decline. https://www.sciencealert.com/huge-study-links-99-of-heart-attacks-and-strokes-with-four-risk-factors

Tiny protein clusters, called alpha-synuclein oligomers, anti-microbial proteins that may be very early triggers of Parkinson’s disease, have been directly visualized for the first time. https://www.sciencefocus.com/news/hidden-trigger-parkinsons

Three researchers won the Nobel Prize for their work on regulatory T cells (Tregs), unraveling how the immune system knows to attack foreign entities and not our own cells. https://www.cnn.com/2025/10/06/science/nobel-prize-medicine-brunkow-ramsdell-sakaguchi-immune-system-intl

Those who ate the most riboflavin (vitamin B2) cut their dementia risk in half compared to those who ate the least in a new longitudinal study. Folate (B9) and vitamin B6 also reduced risk. https://www.eatingwell.com/riboflavin-for-lower-dementia-risk-study-11824281

Increasing daytime sleepiness and worsening circadian rest-activity rhythms were associated with a higher risk of dementia. This tiredness could be a symptom of an energy imbalance, where your brain demands more than it is being supplied. https://www.neurology.org/doi/10.1212/WNL.0000000000213403

Women are more likely to develop Alzheimer’s-related dementia than men, but a new study has found that men have higher hospitalization and mortality rates than women following a dementia diagnosis, even after adjusting for age and comorbidities. https://www.medpagetoday.com/neurology/dementia/116964

A precise, personalized brain stimulation was found to ease depression rapidly, and even reduced anxiety. The connection between mental health and dementia means this research is worth following. https://newatlas.com/mental-health/hd-tdcs-brain-stimulation-precise-depression/

In a new preprint, Dr. Ram Rao found that the ReCODE protocol significantly reduced depression scores in patients with cognitive impairment. Read on to learn why ReCODE helps: https://www.apollohealthco.com/precision-medicine-protocol-shows-dual-benefits-improved-cognition-and-reduced-depression/

A recent study has found that high sugar intake can increase your risk of dementia by as much as 43%. Researchers also found that genetics can influence these numbers even further. But we already knew that, didn’t we? https://www.eatingwell.com/sugar-dementia-risk-study-11787744

We’ve highlighted the link between pollution/toxins and Alzheimer’s for years. Please take precautions, avoid polluted air when possible, use HEPA filters (or similar) in your home, and detox when air quality is low. https://jamanetwork.com/journals/jamaneurology/article-abstract/2838665

An antiparasitic used to treat pinworm can help lower the tau levels in mice. The drug targets misshapen nuclear speckles and restores their shape, reducing tau levels without causing cellular stress. https://today.ucsd.edu/story/antiparasitic-drug-shows-power-against-alzheimers-and-dementia

Join Judy Benjamin and me this Monday, September 29th at 11:00 am PT as we go LIVE to celebrate Judy’s incredible 2,000-mile milestone on her walk across America. To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_UsefeGqwRTu1XnlFUw905Q#/registration

Recent research from Brazil showed those consuming the greatest amount of these sweeteners experienced a 62% faster cognitive decline. https://www.medscape.com/viewarticle/sugar-substitutes-not-so-sweet-brain-health-2025a1000nes

Can exercise prevent or help treat cancer? According to new research, yes. The study found that a single exercise session of resistance or high-intensity interval training increased anti-cancer myokines and reduced the growth of cancer cells. Wow. https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/

According to Dariush Mozaffarian, the best vegetable (or really, fruit) for heart health is the avocado. It can help lower LDL cholesterol, and provides healthy fiber, potassium, & antioxidants. https://www.realsimple.com/the-one-vegetable-for-better-heart-health-according-to-a-cardiologist-11774184

Looking for a way to put all of your dementia-fighting skills to work? Visiting new locations stimulates your brain, gets you moving, and helps keep you social, helping to keep your brain sharp. https://nypost.com/2025/08/12/health/your-summer-travel-could-be-helping-you-prevent-dementia-heres-how/

A new analysis of the efficacy of lecanemab and donanemab found a high likelihood that the antibodies had no effect for those with 2 copies of APOE4. Given the higher risk of side effects, they recommend these individuals should not receive the treatment. https://pubmed.ncbi.nlm.nih.gov/40225236/

Herpes simplex virus type 1 is becoming an established risk factor for dementia, and evidence is building that treatment with antivirals for various infections may reduce dementia risk. https://www.medscape.com/viewarticle/can-preventing-treating-herpes-reduce-dementia-risk-2025a1000kna

A heart drug slowed accumulation of phosphorylated tau protein-217 (p-Tau 217) in those with cardiovascular disease in a new trial. While the drug targets cholesterol, much of the benefit may simply come from improved cardiovascular health. https://www.medpagetoday.com/meetingcoverage/aaic/116765

A combination of epigallocatechin gallate and nicotinamide can increase clearance of amyloid beta, improve energy metabolism, and reduce oxidative stress. https://news.uci.edu/2025/08/06/uc-irvine-researchers-find-combination-of-natural-compounds-for-brain-cleaning/

A decades-long study has found that superagers can have brains similar to those of people 30 years younger. The thing they seemed to have in common was active social lives (another recommendation of our protocol). https://www.popularmechanics.com/science/health/a65632918/superagers-brains/

Surprisingly, nighttime light doesn’t just ruin your sleep - it can disrupt your body in many other ways that also increase your risk of cognitive decline and dementia. https://scitechdaily.com/the-surprising-ways-nighttime-light-wrecks-your-brain-and-body/

We’ve long documented that reducing stress has cognitive benefits, but how do you actually do it? The Independent documents four easy techniques that are worth a try. https://www.independent.co.uk/health-and-fitness/four-brain-hacks-stress-reduction-vagus-reset-b2806735.html

New research has found that COVID-19, as well as a bacterium causing pneumonia (Chlamydia pneumoniae), can increase your risk of dementia. In our protocol, we include treatment of such infections. https://medicalxpress.com/news/2025-07-links-covid-bacterial-infection-alzheimer.html

I recommend our KetoFLEX 12/3 program, but a recent study found that the other four diets listed above can also reduce your risk of dementia. https://www.sciencealert.com/major-study-links-4-healthy-diets-with-up-to-28-lower-dementia-risk

Researchers found that grandparents who spend a moderate amount of time caring for their grandchildren had a 24% less likely chance of developing dementia. https://www.mcknights.com/news/moderate-amount-of-caring-for-grandchildren-protects-against-dementia-in-seniors-new-study-finds/

August 4th, 2025 will forever be known as Dr. Judy Benjamin Day in Austin, Texas! https://youtube.com/shorts/UuDxZgumSfQ?si=ZnSJd0GcU1mE1xaU

New research has found that loss of visual sensitivity can predict dementia 12 years before diagnosis (one surprise in this work—watching TV or reading books was associated with reduced risk). https://www.sciencealert.com/your-vision-can-predict-dementia-12-years-before-a-diagnosis-study-discovers

A new study has found that fasting produces ketones like β‑hydroxybutyrate that attach themselves to misfolded proteins and steer them to the brain’s recycling system. https://www.earth.com/news/ketone-bodies-compound-produced-during-fasting-improves-brain-health/

Join Dr. Dale Bredesen and Judy Benjamin on Tuesday, August 5th at 1:30pm PT to celebrate Judy reaching the halfway mark of her inspiring walk across America. Register here: https://us02web.zoom.us/webinar/register/WN_jnKH1ZkTSG2yS8otnlfdQw#/

Cycling during middle age can significantly lower your risk of developing several different types of dementia. Great to see that so much new research is confirming what we’ve been saying for over a decade. https://www.thecooldown.com/outdoors/cycling-reduces-risk-dementia-brain-health-study/

Achieving an Ageless Brain is profoundly influenced by what you eat. Real Simple highlighted 6 foods centenarians almost never eat, and their list aligns well with KetoFLEX 12/3. https://www.realsimple.com/foods-centenarians-rarely-eat-8737190

Looking forward to joining The DNA Company for a webinar because they understand that your genes are not your destiny! Come join us for this talk on the role of APOE, our research, and how you can protect yourself. https://us02web.zoom.us/webinar/register/WN_kIlN9pf7S6yQ_vMJtQF6ZA

Disrupted sleep prevents your body and brain from eliminating toxins and shrinks the parts of the brain known to provide early indicators of cognitive decline. https://www.psypost.org/poor-sleep-may-shrink-brain-regions-vulnerable-to-alzheimers-disease-study-suggests/

Please join me to earn up to 30 CE/CME credits. We'll explore crucial topics and deliver actionable insights on treating conditions such as dementia, anxiety, and depression. You can learn more at https://www.immh.org/?ref=1218.

I joined the Root Cause Medicine Podcast to discuss cognitive decline, the role of supplements, and the role of the brain’s microbiome. https://podcasts.apple.com/us/podcast/the-ageless-brain-dr-dale-bredesen-on-preventing/id1589219026?i=1000712583518

Broccoli is antioxidant-rich, high in brain-healthy nutrients like choline, flavones, vitamin C, and CoQ10, and aids in detoxification. From July 2nd to the 8th, new users of Trifecta’s new KetoFLEX12/3 can get free broccoli for life by using the code apollolife: https://ketoflex123.com/

In a “shocking” development, researchers at Harvard just discovered what we published more than a decade ago: you can prevent and, in some cases, even reverse Alzheimer’s. Welcome to the 21st century, Harvard.

Anticholinergic medications correlate with increased dementia risk. This includes drugs like Benadryl & Advil PM. Newer drugs like Claritin and Zyrtec, which don’t cross the blood-brain barrier as much, are likely better. https://www.womenshealthmag.com/health/a64804619/antihistamines-dementia-risk/

Alzheimer’s is a complex syndrome with dozens of contributing factors, from inflammation and insulin resistance to toxin exposure and, as this study shows, issues with cellular repair. https://news.mit.edu/2025/scientists-discover-potential-new-targets-alzheimers-drugs-0520

Join Dr. Dale Bredesen and Judy Benjamin as they celebrate Judy crossing the 1,000-mile mark and discuss her ongoing journey across the USA. Register here: https://us02web.zoom.us/webinar/register/WN_qsOrP1YJSZ2hjWtq_dJLzg#/registration

This research should compel us all to view sleep not as a luxury, but as a critical and modifiable factor in the fight against cognitive decline. https://www.news-medical.net/news/20250528/Sleep-disorders-predict-dementia-risk-years-before-diagnosis-study-shows.aspx

California, Arizona, and New Mexico are done. Judy’s made it to TEXAS! In a recent interview, she discussed her inspiring walk across the country from San Diego to Florida. Should we plan a live video to celebrate 1,000 miles??? Read more: https://www.judywalks.com/journal/ktsm9

A new study found that smart devices, like your iPhone or smart watch, can accurately assess your cognitive health without an appointment. One more way to smartly take your health in your own hands. https://www.eurekalert.org/news-releases/1075713

Time in the garden increases physical activity and social connection, improving factors that lead to Alzheimer’s. https://www.bbc.com/future/article/20250509-how-gardening-boosts-brain-health

Just 10 days of physical inactivity can increase insulin resistance and increase the levels of biomarkers in the brain associated with Alzheimer’s disease. The best way to combat this change? Move your body. https://www.futurity.org/physical-activity-brain-health-decline-3265552/