Jessica Honorato-Mauer (@jhmauer.bsky.social)

Characterizing features affecting local ancestry inference performance in admixed populations This work examines accuracy rates and error modes for local ancestry inference (LAI) using simulated admixed cohorts. Our findings inform best practices for high-quality LAI, which is vital for genomics applications in admixed populations. We further highlight the need for increased inclusion of underrepresented populations in reference panels. https://www.cell.com/ajhg/abstract/S0002-9297(24)00447-6