Steun onderzoek naar gentherapie voor Vanishing White Matter (VWM)! Jouw steun brengt ons dichter bij een oplossing! Het onderzoek biedt nieuwe hoop voor patiënten en families. Doneren en meer info via de link: www.zzf.nl/zzf-onderzoe... #VWM #ZeldzameZiekten #Gentherapie

- job alert - Will you become our colleague at the Amsterdam Leukodystrophy Center? See the PhD opening below, focusing on the molecular basis of fluid regulation by astrocytes in the brain. Apply using the link below: 🔗 werkenbij.amsterdamumc.org/en/publicatie-1179368

🚨 PhD position in astrocyte physiology! Join us in Amsterdam to explore how astrocytes dynamically regulate brain water flow! Apply using the link below: 🧠🔬🌍 🔗 werkenbij.amsterdamumc.org/en/publicatie-1179368 #Neuroscience #PhD #Astrocytes #MLC #SUPERGLUE

Fresh from the lab! In this new paper, PhD student Sven Kerst shows how phenotypes observed in isolated cell models for the leukodystrophy MLC are also observed in intact astrocytes in acute brain slices! Glia | Neurobiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...

Marjo van der Knaap has just opened the leukodystrophy symposium in Amsterdam, celebrating both 25 years of the ALC as well as Marjo’s farewell from clinical tasks. We are very excited about the coming 2 days of white matter science!

A new study from the ALC reveals how Eif2b5 mutations in different brain cell types (including oligodendrocytes and astrocytes) contribute to VWM. Our findings challenge the idea that malfunction of a single cell type drives the disease. Find the article at: academic.oup.com/brain/advanc...

⭐ New paper alert ⭐ Our recent work on anesthetics as potential stressor inducing acute decline in patients with vanishing white matter (VWM), is now published. 📖: www.sciencedirect.com/science/arti....

Excited to share our latest paper! We argue that in MS, the primary immune attack isn’t on myelin or myelinated axons — but on the ion & water homeostasis machinery in astrocyte endfeet. A short thread on this new perspective 1/11

My first post in the sky is a: Job Alert! We are looking for a PhD student to study astrocyte dysfunction in the rare neurological disease MLC. Looking for a challenge? See the job advertisement below! werkenbij.amsterdamumc.org/en/vacatures...