We begin the New Year with two preprints on hypothalamic development. The first, part of a long-term collaboration with Marysia Placzek’s group, investigates the organization of the developing forebrain, and show that current models are (mostly) incorrect./1 www.biorxiv.org/content/10.1...

Our second preprint, which was spearheaded by @thomasdwkim.bsky.social, uses single-cell multiomic analysis to identify gene regulatory networks controlling neurogenesis and cell fate specification in mouse hypothalamus and prethalamus./1 biorxiv.org/cgi/content/...

Brought to life through the magic of Blender... For more details and more movies go to our preprint www.biorxiv.org/content/10.1...

Our second New Year preprint on hypothalamus development, led by @thomasdwkim.bsky.social Major insights into hypothalamic GRNs, functionally tested in mutants, and behavioural importance of prethalamus-derived inhibitory neurons @sethblackshaw.bsky.social www.biorxiv.org/content/10.1...

Excited to present our new preprint clarifying forebrain developmental organisation. Complex growth patterns shape the forebrain but distort the A-P + D-V axes, hence prior confusion over brain layout. Big love for chicken embryos, simpler to interpret than mouse 🐣1/3 www.biorxiv.org/content/10.1...