An increasing number of UG students appear to be struggling with mathematics. What we thought was a local, transient issue may actually be part of a wider, possibly global, problem. maa.org/math-values/... #math #engineering #edu

In Julia, function composition isn’t just notation… it's executable math > f(x) = x^2 + 1 > g = f ∘ sin > g(pi/2) # gives 2 #julialang #joyofcomputing #computing

A university is closing its Department of Statistics due to financial constraints. Really? In this age, where mathematics, computing, and AI/ML dominate every industry, closing a Statistics Department doesn’t seem like a good business decision. #justsaying nebraskaexaminer.com/2025/12/05/t...

To what extent can the foundations of thermodynamics & stat physics be built purely from combinatorics and probability—without relying on the usual concepts like work, heat, and energy? Are there any textbooks that develop the theory primarily from a probabilistic perspective only?

Don't be clueless! Better, understand how Julia thinks: @code_lowered 2 + 3 @code_lowered 2 + 3.0 @code_lowered 2.0 + 3.0 Code better. Code smarter. #JuliaLang #computing #sysbio #systemsbiology #qbio

High-throughput omics studies > lots of data transformations > 5,000 correlations to be tested through experiments. Toy models with few parameters > the design principles behind the complexity of Life. True Systems Biology: fewer spreadsheets, more ‘Aha!’ moments. #sysbio #mathbio #physicsoflife

Why burden memory? Take a sneaky peek and get the job done! A = rand(5,5) W = @view A[2:4,2:4] # take a peek, no copying @views W[1:2, 1:2] .= 0 # sneakily mutate A # check the mutation #julialang #computing

Explaining non-equilibrium systems to students: ‘Imagine a system that refuses to relax.' Students: ‘Like us?’ #justforfun #teaching #physicsoflife #physicsoflivingmatter

Schrödinger’s cat called. It is live and it wants a break. It didn’t sign up to explain superposition to every social media users. Enough!

Using ± in Julia code? Yes, because real models don’t come with exact parameters. using DifferentialEquations, MonteCarloMeasurements k = 1.0 ± 0.1 u0 = 1.0 ± 0 prob = ODEProblem((u,p,t)->-k*u, u0, (0,5)) sol = solve(prob) mean(sol[end]) #JuliaLang #computing

Temperature is not just a thermometer thing. Physicists, chemists, biologists, economists, and data analysts all use it differently. Maybe one day we'll find a single rule that links them all. Until then, temp keeps its cool by being complicated.

Another review article worth bookmarking: Signed Networks: theory, methods, and applications." arxiv.org/abs/2511.17247 Perfect for my Systems Biology course. #sysbio #complexsystem #graph #network #compbio #mathbio

Many bugs don't scream. They whisper in wrong units. Using units in your code can save you. Again, Julia helps in that. using Unitful D = 0.01u"mm^2/s" # 0.01 mm^2 s^-1 t = 100u"s" # 100 s √(2D*t) # 1.4142 mm #julialang #computing #sysbio #systemsbiology

Identical genome. Same environment. Totally different life choices. Turns out even cells have an identity crisis. #sysbio #physicsoflife

I get confused when philosophers and scientists debate “reality.” If I slap someone, they feel pain and may hit back. That’s real. So clearly, I’m missing something much deeper. #justsaying

In biology, we’re still busy naming T cells and debating EMT or autophagy — a bit like arguing over bird names while the real wonder lies in understanding how they fly. #complexsystem #PhysicsOfLife #sysbio

Dear developmental biologists, Julia comes with a Zygote that auto-differentiates. 😀 using Zygote f(x) = x^2 + 3x + sin(x) f'(2.0) # returns 6.58385 #Julialang #mathbio #qBio #compbio #sysbio #systemsbiology

At the beginning of this year, Active Matter researchers published a 'review of reviews' — yes, a meta-meta study. When your field grows so fast, you need a map of the maps. Worth bookmarking. link.springer.com/article/10.1... #activematter #physicsoflife #physicalbiology #complexity

Is it weird that I prefer old biology papers—the ones with two figures, zero rainbow plots, and actual ideas? Or am I just allergic to 100-page supplements that explain nothing?

Every time I get overwhelmed, I remember- a lot of statistical physics is basically fancy bookkeeping for balls in boxes.

When science books cost a fortune, only publishers win. Open sharing—GitHub, arXiv—helps every learner. Isn’t it time to free ourselves from the 'medieval' prestige of being ‘published by a reputed publisher’? #scicom #edu #doingsciencd

Wet lab? Dry lab? I prefer the Symbolic lab. Math-Bio isn't just HPC runs— derivations & proofs matter too. As always, Julia helps. using Symbolics @variables x y a b c d m n f = [a/(1+y^n)-b*x, c/(1+x^m)-d*y] J = Symbolics.jacobian(f,[x,y]) #Julialang #mathbio #computaionalbiology #sysbio

Calling any large, well-organised dataset "Systems Biology" is a bit like calling a census "social theory." Essential, powerful, and impressive — yes. But the explanations, through generalised theories/models, still have to be earned. #systemsbiology #sysbio #physicsoflife

PhD defense (Dramatized based on real events): You (examiner): That statistics & conclusion are wrong. Needs correction for repeated tests. Candidate: 🤔 (flustered). Supervisor: No issues! 😡 This work is already published. How often do you face such a situation? #worldofbiologists #bio

My physicist friends love universality — until the system starts voting, reproducing, or trading stocks 🤪 #complexsystem #physicsoflife #physicsoflivingmatter #systemsbiology

A = [1, 2, 3] B = [3, 4, 5] x = 9 x ∈ A ∪ B # -> false Writing code using symbols in Julia feels like scribbling in a math notebook — except this one actually runs. It takes some time to get habituated, but then you get hooked. #julialang #computing

Every time I try to post on #mathbio, I realize 300 characters can’t hold a nonlinear thought!

In the age of AlphaFold, should we still teach homology modeling, threading, and other classical structure prediction algorithms? In the era of generative AI, the hardest question in teaching isn’t what to include—it’s what to leave out. #teaching #education #computationalbiology #AI

With a channel capacity of one bit, cells have ruled the world for millions of years. Maybe we need a different information theory to understand them. #complexity #systemsbiology #complexsystems

PS Dodds cheekily reimagines the entire history of science as a three-volume saga. Beneath the wit lies a serious claim: complex systems aren't a fad but the long-awaited finale of scientific understanding. arxiv.org/abs/2511.00368 #complexity #systemsbiology

Robotic Experiment > Data > AI-driven [Model > Hypothesis > Experimental Design] > Robotic Experiment: This "closed-loop science" is set to become a reality soon, cutting costs & increasing efficiency. But data is not the limiting factor in Science; Our limited abstraction & generalization are.

Yes, current LLMs hallucinate and fail in many silly tasks. Current AI is surely not the same as human 'intelligence.' But why do we get hyperactive on social media with glee every time we find an error by an AI agent, LLM, or robot? Our existential crisis?

Julia keeps it rational. 1//3 + 1//6 == 1//2 Exact math. No floating-point drama. #JuliaLang #lovingJulia #sillyposts

Statistical physics was built to understand gases. Now we use it to understand flocks, tissues, and tumors. Same mathematics, new meanings—order out of interaction. Perhaps we should develop new thermodynamic variables beyond V, P, and T that are more suitable for living systems. #complexsystems

Between the animate and the inanimate lies a missing theory — not of matter, but of matter becoming intention. Or the concept of teleonomy is just another trap? Possibly! #complexity #physicsoflife

Physicists see the forest, mathematicians see the pattern, & biologists... name every tree, catalog leaf shapes, & write three papers on bark texture before asking why forests exist. Wish my friends from the Biology community would read and re-read the old classic: sciencedirect.com/science/arti...

If I want to teach undergraduate students about driven non-equilibrium systems, which two toy models should I choose? The mathematics must be intuitive, and the simulations must be easy. What do you suggest? #statmech #physics #complexsystem #systemsbiology

In #Julia, even the script evolves with time (without mutation) 😃 julia> @time sum(rand(10^7)) [0.086688 seconds, 57.81% gc time] julia> @time sum(rand(10^7)) [0.026221 seconds, 29.82% gc time] . . julia> @time sum(rand(10^7)) [0.017704 seconds, 2.34% gc time] #Julialang #computing

Gradient systems give you landscapes. Non-gradient systems give you the weather. That's why cellular fate feels more like climate chaos than a downhill stroll on Waddington's landscape. #systemsbiology #dynamicalsystems #complexsystems

How can we design complex computational systems using synthetic biology? Check our paper, where we use space as a computational element, dramatically reducing communication requirements while allowing modularity, reusability, scalability & minimal cell engineering. journals.plos.org/ploscompbiol...

Embryonic development is robust but fluctuations and variations are inevitable. Nature smartly sells those variations as features not bug. #systemsbiology #complexsystems

LLMs don’t live—yet they learn, adapt, and hallucinate. Strange! Is not it? Biologists need to rethink the key ideas of Life. #physicsoflife #mathbio #complexity #systemsbiology

Does a cell have a 'mind' - say a proto-mind or basal cognition? Although it was once a fringe idea, recent experimental and mathematical works are accumulating in its support. Here is an interesting recent work: www.biorxiv.org/content/10.1... #complexsystem #systemsbiology #sysbio

Data-driven modeling of complex biological systems Thank you for joining us at today's NITMB Seminar with Cody FitzGerald, James S. McDonnell Foundation Postdoctoral Fellow at Northwestern University! 📽️ Watch the seminar recording - www.youtube.com/watch?v=B2Y9...

If you have to design a 40 hr UG course on Computational Biology, what topics will you include in the syllabus? As I see across institutes, this course is heavily biased to protein structure, molecular dynamics simulations and drug design. #compbio #qbio

f(x::Int, y::Int) = x + y f(x::String, y::String) = x * y # In Julia, even functions believe in pluralism. #JuliaLang #FunInComputing #computingjokes #computing

Is it only me or for everyone- the feeds in the Bluesky Android app updates only when I use certain networks (ISPs) that too with lag. #bluesky #bsky

Switched to Julia 3 years ago. Still can’t uninstall MATLAB — held hostage by the interactive GUIs of dfield, pplane, and matcont. #JuliaLang #computing #dynamicalsystems

Reciprocity is overrated. Ask any cell. #NonReciprocal #ActiveMatter #Physicsoflife

Teaching Gillespie algorithm in the Systems Biology class and it reminds that Life is a process with long stretches of exponential calm punctuated by bursts of stochastic drama. #stochastic #random #mathbio #systemsbiology #sysbio