Tycho Mevissen (@tychomevissen.bsky.social)

Let's get this site started. I'm excited to share that our work on transcription-coupled DNA repair is now published! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples lesion-stalled RNA Pol II to TFIIH. 🧬🐸 ➡️ cell.com/cell/fulltex...

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STK19 positions TFIIH for cell-free transcription-coupled DNA repair Together with structural analyses, a cell-free system for transcription-coupled nucleotide excision repair (TC-NER) shows that STK19 is an integral component of the TC-NER complex that couples RNA pol... https://cell.com/cell/fulltext/S0092-8674(24)01202-9

over 1 year ago