@binwu1.bsky.social
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Excited to share that our collaboration with Oberdoerffer's lab at NIH has just published on
@nature.com
.
www.nature.com/articles/s41...
. We showed that the nucleotide modification ac4C enhances translation yield and fidelity of chemically modified synthetic mRNAs compared with industrial standard.
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15 days ago
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Exited to share our recent publication by Ana De La Cruz from Johns Hopkins Biophysics. We visualized single mRNAs, their translation status and a regulatory factor in live cells.
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Single-protein/RNA imaging reveals ZNF598 as a limiting factor in resolving collided ribosomes | The EMBO Journal
imageimageRibosomal quality control (RQC) ubiquitin ligase ZNF598 distinguishes transient ribosome collisions from permanent ones. Here, simultaneous imaging of protein-mRNA binding dynamics and trans...
https://www.embopress.org/doi/full/10.1038/s44318-025-00523-z?utm_source=rct_congratemailt
12 months ago
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