Martijn Verdoes (@mverdoes.bsky.social)

Happy to finally see this multidisciplinary collaborative effort with the Scheeren lab (LUMC) out: ubi-tagging! Antibody engineering using the ubiquitin conjugation machinery. Great teamwork spearheaded by Angela el Hebieshy and Zach Wijfjes. www.nature.com/articles/s41...

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Site-directed multivalent conjugation of antibodies to ubiquitinated payloads - Nature Biomedical Engineering A technique for the site-directed conjugation of antibodies via the small-protein ubiquitin allows for the efficient multivalent conjugation of antibodies and nanobodies to fusions of ubiquitin with m... https://www.nature.com/articles/s41551-024-01342-z