An experimental gene-editing treatment shows promise for permanently lowering levels of cholesterol and triglycerides, possibly helping cut the risk for heart disease. n.pr/4hPhrQp

After several days of dry, balmy weather and temperatures reaching into the 90s, California is expected to see a dramatic change in the weather this week, likely beginning on Wednesday when a storm system will usher in lower temperatures and heavy rain and snow.

Roman theatre at Amman, Jordan. It is a 6,000-seat, 2nd-century Roman theatre when the city was known as Philadelphia. A Greek inscription on one of the pillars indicates that this theater was built in honour of Emperor Antoninus Pius (AD 138–161). #RomanSiteSaturday

I sometimes wonder when I see articles like this. | #cancer #genetics #heritability #syndrones #LynchSyndrome

James Watson has died. www.nytimes.com/2025/11/07/s...

On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...

Identification of Therapeutic Gene Targets in Triple-Negative Breast Cancer: A Hybrid Approach Integrating Semidefinite Programming, Boolean Simulation, and Druggability Analysis https://www.biorxiv.org/content/10.1101/2025.11.05.686831v1

Insurance companies aren’t just players in the fight with doctors over money; they’re also the referees. They produce their own guidelines on when to pay claims. If a doctor appeals a denial, insurers make all the initial decisions. (Published April) By @tchristianmiller.bsky.social

Over the past decade, there has been a rush of scholars moving across the Pacific to China, drawn by Beijing’s drive to become a scientific superpower. But President Trump’s return to the White House has turbocharged this effort.

BChemXtract - a ChemDraw parser and structure extractor - is our first open source software project and is available on @github: 🔗 https://github.com/Beilstein-Institut/BChemXtract #openscience #opensource #fairdata #fairchemistry #Cheminformatics #github #beilsteincheminfolabs #bchemxtract

BChemXtract, the new @BeilsteinInstitut ChemDraw parser and structure extractor, uses CDK 2.11 <properties> <cdk.version>2.11</cdk.version> </properties> https://hessen.social/@BeilsteinInstitut/115497448450303612 #Cheminformatics #chemistry #openscience

No idea why people keep saying this is socialism. When Trump says "us" he isn't talking about Novo Nordisk giving a piece of the company to the US government, he's talking about them giving a piece of the company to him and his crooked ass sons.

On the same day world leaders arrived at the COP30 summit in Brazil to push for more action on climate change, Greece announced it will start drilling for fossil fuels in the Mediterranean Sea — with US help.

Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.

a form developed from tumor lysate -inactive cancer cells from actual tumors- to mimic the complex mixture of proteins in human cancers. The vaccine was shown to protect against a number of different types: 88% of mice from pancreatic cancer, 75% from breast cancer, and 69% from melanoma. The

Something that was conserved between pig and human systems. This is particularly useful in the context of anti-pancreatic cancer effects of statins as shown in a recent article: www.cell.com/cell-stem-ce... /3

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

A new treatment in Stage 3 trials for pancreatic cancer with amazing promis www.yahoo.com/news/article...

Daraxonrasib was given to 83 patients with pancreatic cancer that had spread after treatment. Over more than 16 months, 90% of them saw no tumor growth. Next steps: The pill will undergo a new, fast-track review process approved by the FDA.

Cell populations in human breast cancers are molecularly and biologically distinct with age "how age affects cells in the breast tumor microenvironment or how they contribute to age-related pathology." www.nature.com/articles/s43...

:') www.theverge.com/report/81448...

Magnetoelectric nanotherapy shrinks pancreatic tumors and extends survival in preclinical study | #PancreaticCancer #cancer

People who receive stem cell therapy within a week of their first heart attack have nearly a 60 per cent lower risk of developing heart failure years later

mRNA vaccine builds viruslike nanoparticles inside the body The self-assembling system produces higher antibody levels in mice than conventional COVID-19 vaccines. cen.acs.org/pharmaceutic... #chemsky 🧪

Novo Nordisk raised its Metsera bid to as much as $10B, topping Pfizer’s latest $8.1B offer as the two pharma giants battle for the obesity biotech.

Jennifer Doudna’s Azalea Therapeutics launched with $82M to develop in vivo CAR-T therapies using a new CRISPR delivery system called EDVs, or Enveloped Delivery Vehicles.

"There's just a lot of great momentum and buzz in Union Square right now."

Changing just one of the materials used in lithium-ion batteries could prevent the uncontrollable fires that erupt if they are pierced or bent.

Fibromyalgia pain: Scientists may have finally solved the mystery

Google Translate adding model picker for 'Advanced' or 'Fast' translations | #AI #Google

University of Surrey researchers mimic brain wiring to improve #AI

I'm an infrequent watcher of baseball games at best. But when I do, I'm reminded that what makes the National Pastime so emblematic of this country, is that a group of immigrants can get together to achieve something great.

The LA Dodgers win the World Series

I love #art that transports you through time. Whether it's a #Vermeer, #Caillebotte, #Tissot or one of the PreRaphaelites. Recently the work of Jean Béraud appeared in my feed. He was truly a prolific painter of Belle Epoque life in Paris. Not just paintings of the well-to-do, but of every day life.

How fair are the algorithms that decide who gets information online? Our new paper in PNAS Nexus shows that maximization algorithms, the ones used to pick “influencers” in social networks, unintentionally deepen inequality. 🧠 Sekara, Dotu, Cebrian, Moro & García-Herranz 🔗 doi.org/10.1093/pnas...

🤝 I’m forming a focus group to synergize and supercharge evidence‑based science communication on social media. Want to join? Drop a comment below or DM me. #SciComm

My quote of the day Abraham Lincoln

British electricity grid is on a real renewable (windy) roll this week and at the moment, during the day, we're exporting more electricity (to Norway, Ireland, Belgium and Denmark) than we're producing in fossil fuel generation. We often do this overnight - during the day is ... a bit more novel!

From @plos.org #Computational #Biology | Ten rules for a structural bioinformatic analysis | i like Recommendation #10: Visualize everything! | #Bioinformatics #Education #Recommendations #NotSimpleRules 🧬 🖥️ 🧪 🔓 CC/ @ppalagi.bsky.social ⬇️ journals.plos.org/ploscompbiol...

The United States was the leading destination for top scientists from all over the world. That is ending. Politicians ended it. It will cripple our future competitiveness. And it’s such a bitter tragedy. Almost no Americans, Conservative or Liberal, grasp what is now being stolen from them.

We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word www.scripps.edu/news-and-eve...

🟣November is Pancreas Cancer Awareness Month🟣 PDAC is the 3rd leading cause of cancer death in the US & is projected to be 2nd by 2030. Survival improved from 4% in 1998 to 13% in 2025, thru efforts like those of Lustgarten.org, the largest private funder of pancreas research. lustgarten.org/pcam/

I was searching through YouTube recently for videos of the RCSB office hours webinars when I saw all these truck videos in my search results. What do trucks have to do with proteins?| #AlgorithmFail

Register Now for Webinar: Exploring Integrative Structures with RCSB PDB On November 12, learn how to explore PDB structures determined using integrative and hybrid methods with RCSB PDB tools

New bird flu vaccine could tackle multiple variants with one shot www.erasmusmc.nl/en/...

The Python Software Foundation rejected a $1.5 million U.S. government grant because it required them to renounce all diversity, equity, and inclusion initiatives. www.theregister.com/2025/10/27/p...

In this week's Peer Review: OrbiMed-backed Brenig Therapeutics changes CEO, and Evaxion recruits Adaptimmune's Helen Tayton-Martin as next CEO. Read the full job update: