Florian Sure
@f-sure.bsky.social
📤 7
📥 17
📝 2
Postdoc in Renal Physiology
@FAU.de
Erlangen-Nürnberg, Active Member of @DLRG
We have a new paper out in Pflügers Archiv! 🎉 We show that acute activation of ENaC by SGK1 critically depends on cleavage of the γ-subunit, indicating an interaction between kinase and protease pathways.
doi.org/10.1007/s004...
#ENaC
#SGK1
#Physiology
#IonChannels
#KidneyResearch
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Acute activation of human epithelial sodium channel (ENaC) by serum and glucocorticoid inducible kinase 1 (SGK1) requires prior cleavage of the channel’s γ-subunit at its proximal cleavage site - Pflü...
Serum and glucocorticoid inducible kinase 1 (SGK1) is a key regulator of the epithelial sodium channel (ENaC). In rat ENaC, the serine residue 621 (S621) in the channel’s α-subunit is essential for ac...
https://doi.org/10.1007/s00424-025-03099-z
6 months ago
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reposted by
Florian Sure
Nanion Technologies
7 months ago
In a recent study, researchers developed and validated an automated
#patchclamp
(
#APC
) approach using the SyncroPatch 384 platform to detect
#ENaC
- mediated currents in a high-throughput format. Read more here:
www.nanion.de/news/automat...
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Automated patch clamp for ENaC drug discovery - Nanion Technologies
The epithelial sodium channel (ENaC) plays a central role in regulating sodium balance, blood pressure, and pulmonary fluid clearance. Despite its clinical relevance, progress in discovering new ENaC-...
https://www.nanion.de/news/automated-patch-clamp-for-enac-drug-discovery/
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Happy to share our recent research
@fau.de
on how to measure ENaC using automated patch clamp technique on a platform developed by
@naniontech.bsky.social
🎉
doi.org/10.1007/s00424…
#research
c
#ENaC
a
#APC
P
#Science
ce
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https://doi.org/10.1007/s00424…
7 months ago
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