A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis. rdcu.be/d9iRG

Thrilled to share that our paper is now online in Nature Immunology! Huge thanks to all the amazing lab members and collaborators who made this possible. Science is a team effort, and I’m grateful to be working with such a fantastic group. #MastersLab#inflammasomes www.nature.com/articles/s41...