@lpil.uk Looks like Bases in Obsidian will be getting an API either the ability to create new views obsidian.md/changelog/20...

GOOD NEWS! Researchers have unveiled a promising new vaccine that generates a powerful immune response against HIV and other viruses including SARS-CoV-2 and influenza with just ONE dose. By combining immune-boosting adjuvants, the vaccine encourages the body to generate more antibody variations.

Well now, would you look at that? A massive, 26-YEAR-LONG study of MORE THAN 2.4 MILLION people in Sweden found found NO EVIDENCE to support a causal link between acetaminophen (the API in Tylenol) use during pregnancy and increased risk of autism, ADHD, OR intellectual disability in children.

GOOD NEWS! For the first time ever, Huntington's disease has been successfully treated. A groundbreaking new miRNA treatment, AMT-130, slowed the progression of the disease by 75%. These results are likely to support the first approval of a genetic treatment for the rare neurodegenerative condition.

GOOD NEWS! A new cancer vaccine has shown progress in triggering POWERFUL and LASTING immune responses in patients with pancreatic AND colorectal cancer. The vaccine, known as ELI-002 2P, targets mutant KRAS proteins AND had a huge impact on PREVENTING or DELAYING cancer recurrence in patients.

It was meeting an out trans person that helped me realize I myself was trans. It was other out trans people that helped me navigate transitioning. And it was even more out trans people who inspired me to keep going when times were tough. Now I am an out trans person, and I hope to inspire others.

GOOD NEWS! Researchers have made a HUGE breakthrough towards a UNIVERSAL antiviral. By targeting sugar molecules found on the surface of many viruses that SHARE structural similarities, they identified FOUR compounds that successfully BLOCKED infections from SEVEN different viruses.

WELL NOW, would you look at that? A massive GLOBAL study revealed COVID-19 vaccines utilizing mRNA technology PREVENTED OVER 2.5 MILLION deaths WORLDWIDE between 2020 and 2024. It reveals that vaccinations didn’t JUST protect against illness. They PRESERVED nearly 15 MILLION years of human life.

@theerlef.bsky.social Good to see the EEF on bluesky! Small suggestion: Add the EEF website link to the account bio so people can check it out ^^ The EEF can also verify the erlef.org domain for use on bsky: seanthegeek.net/posts/how-bl...

GOOD NEWS! For the FIRST time ever, and after MORE THAN 30 YEARS of HIV vaccine clinical trials, researchers have developed a vaccine that has SUCCESSFULLY generated TIER 2 broadly neutralizing antibodies (bnAbs) against HIV and BLOCKS viral infection in vaccinated PEOPLE.

GOOD NEWS! Researchers at the University of Florida have developed a UNIVERSAL vaccine that dramatically BOOSTS the immune system’s ability to fight tumors- even WITHOUT targeting a SPECIFIC cancer type. It has the potential to do away with chemotherapy, surgery AND radiation treatment.

Vaccines save lives. They are safe and effective. And no, they do not cause autism.

WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders. Aluminum is an ADJUVANT. It ENHANCES your immune response to a vaccine. That’s it.

GOOD NEWS! Researchers have revealed a synthetic glycosystem -a sugar-coated polymer nanoparticle- that can BLOCK SARS-CoV-2 from infecting human cells, REDUCING infection rates by NEARLY 99%. Acting as a decoy, the molecule BINDS to the spike protein, PREVENTING it from attaching to real cells.

@mikecaulfield.bsky.social I recently found an LLM UI that might align with your recent thoughts. It takes a file management prompt and suggests how to do it with common command-line tools. Seems like a good example of designing the UI to help learn & practice a skill: selkie.design/substage/

@cabel.panic.com There’s currently a Playdate speedrun on SGDQ ^^ twitch.tv/gamesdonequick

I just sorted through and donated a bunch of old electronics but still couldn’t part with this old macbook air I made towerfall on

GOOD NEWS! A SINGLE infusion of a stem cell-based treatment, VX-880, may have CURED a small group of patients with the most SEVERE form of Type 1 Diabetes. 10 out of 12 patients have remained insulin-INDEPENDENT for OVER a year and the other two patients now need much LOWER doses of insulin. 🧪🧵⬇️

Continuing my process of alienating nearly everyone by posting good thing about LLMs one day and bad things the next. This one is pretty bad. open.substack.com/pub/mikecaul...

Trans kids deserve better. Trans kids deserve kindness. Trans kids deserve to be who they are. Most importantly, trans kids deserve the time to just be kids without having to be someone else’s agenda.

1. The US Transgender Survey has finally been released, and the results are stunning. - <1% of people are less satisfied after HRT. - The most common reason for detransition, pausing transition, or stopping transition is transphobia. The latest from S. Baum. Subscribe to support our journalism.

hey hi I'm in this bundle, please check it out and spread the word if you can! 💙

THIS IS AMAZING! Researchers have made a SIGNIFICANT breakthrough in the quest for an HIV cure. By developing a method that enables the delivery of an mRNA-based therapy to make the virus VISIBLE WITHIN white blood cells, this approach paves the way to FULLY CLEAR the virus from the body. 🧪🧵⬇️

If you get testosterone gel from Strides Pharma Inc, check your lot numbers, benzene was found in it so it's gotten recalled www.chpw.org/provider-cen...

THIS IS HUGE! Researchers at Memorial Sloan Kettering Cancer Center say results of a Phase I trial of an mRNA vaccine aimed at preventing pancreatic cancer show promise. The vaccine PREVENTED the cancer from coming back in patients who had already received treatment for MORE THAN three years. 🧪🧵⬇️

Vaccines save lives. And no, they do not cause autism.

Visibility is not enough if trans people aren’t safe. We need legal protections, access to healthcare and an end to anti-trans policies. On #TransDayOfVisibility, commit to action, not just words.

Every trans person deserves safety, dignity and respect. No exceptions. No conditions. No debate. Visibility is only meaningful if it leads to real change. #TDOV #TransDayOfVisibility

There's an API built into iOS that extracts text from images — maybe the bsky app could pre-fill the OCR'd text of an attachment to give people a head start? cc: @pfrazee.com

You don’t have to be fearless. You just have to be brave enough to act. Courage isn’t about never feeling scared. It’s about doing what’s right despite that fear. Every step forward, no matter how small, means more than you know.

@mmasnick.bsky.social Hi Mike, I deeply appreciate your work. I know you do your best to discern fact from fiction, so I ask that you consider Zeynep Tufekci's work before boosting people who dismiss any possibility of a lab leak, especially an accidental leak. bsky.app/profile/zey....

Speak up when you see transphobia happening. In media, in politics, in everyday conversations. Everywhere! Silence is not neutrality. It’s complicity.

A reminder that women’s sports are kept separate from men’s not to protect women from always losing to men, but rather to ensure that no man ever loses to a woman. I’m not making this up; that’s literally the reason.

hello cis friends this is what people mean by trans genocide if a type of person does not officially exist, then any harm against them cannot be measured or reported this headline change isn't even being caused by an executive order it's simply the NYT editors deciding we don't deserve to exist

The author of SIFT is @mikecaulfield.bsky.social. I first encountered it in 2020. See hapgood.us/2019/06/19/s... I love that the entire point is (re)building context to support interpretation - “reconstructing the necessary context to read, view, or listen to digital content effectively”

@mmasnick.bsky.social Some important context regarding your latest repost: bsky.app/profile/jay2...

After nearly three decades, a Minnesota summer camp for kids with HIV/AIDS is closing and up for sale... because retroviral drugs are so effective that there aren't enough campers. Science works, y'all. www.startribune.com/closure-of-n...

Bluesky’s microblogging-oriented interface is too noisy and scattered for constituent conversations and issue tracking, but a new app — purpose-built on ATProto for constituent relations — could be mighty interesting…

Ursula K. LeGuin: "American science fiction has assumed a permanent hierarchy of superiors and inferiors, with rich, ambitious, aggressive males at the top, then a great gap, and then at the bottom the poor, the uneducated, the faceless masses, and all the women."

We all want to stay connected and share our thoughts and feelings online. But, don't get caught by #misinformation! Use the #SIFT method from @mikecaulfield.bsky.social to evaluate what you see online. Stay smart online and share responsibly! 👇

🛑 STOP. Before you share an article, take a moment to stop and think about the source. Is it a reputable source? Is the author an expert on the topic?

🔍 INVESTIGATE. Do some research on the source. What is their mission? What are their values? Do they have a history of publishing accurate and unbiased information?

✔️ FIND. If you're unsure about a source's credibility, try to find better coverage of the topic from a more reputable source.

〰️ TRACE. If an article makes a claim, try to trace it back to the source. This will help you verify the claim and make sure that it is accurate.