Dean Thomas (@deant94.bsky.social)

Proud to have been a tiny part of this amazing team (Pulis Group) over 8 years ago! Check out new advances in B(C6F5)3 catalysis: pubs.acs.org/doi/10.1021/...

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B(C6F5)3-Catalyzed Coupling of N-Alkyl Arylamines and Alkenes for the Synthesis of Tetrahydroquinolines Tetrahydroquinolines are featured in molecules with wide ranging properties, including those with biological activity and materials applications. This report demonstrates that widely accessible N-alkyl arylamines can be directly coupled with new classes of alkenes to synthesize tetrahydroquinolines. The reaction is facilitated by a commercially available borane catalyst and enables the creation of novel tetrahydroquinoline scaffolds. https://pubs.acs.org/doi/10.1021/acs.orglett.5c03023