@psybalazs.bsky.social
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📥 98
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Got interviewed by the Microdose newsletter on the intersection of
#psychedelic
and
#placebo
research and on why psychedelic research should revisit the long forgotten Zelen design to solve the "know-cebo" problem. Enjoy!
themicrodose.substack.com/p/the-power-...
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The power of “know-cebo”: 5 Questions for data scientist Balázs Szigeti
Szigeti discusses expectancy effects, unblinding, and how researchers might design better studies on psychedelics.
https://themicrodose.substack.com/p/the-power-of-know-cebo-5-questions
8 months ago
2
17
8
Instead of making a bunch of separate
#psilocybin
vs
#alcohol
/
#nicotine
/
#gambling
/
#porn
#addiction
trials, it would make sense to run a single trial where patients with ANY form of addiction are recruited.
8 months ago
1
2
0
I want to highlight a finding from (
tinyurl.com/37n77d9b
) that IMO did not receive enough attention in
#psychedelic
trial geek circles: it shows that the
#placebo
effect is much smaller in psychedelic
#depression
trials than in trials with traditional
#antidepressants
(SSRIs/SNRIs).
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Comparative oral monotherapy of psilocybin, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, ayahuasca, and escitalopram for depressive symptoms: systematic review and Bayesian network m...
PROSPERO, CRD42023469014.
https://tinyurl.com/37n77d9b
10 months ago
1
2
0
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