Large-scale data analysis has revealed a stronger correlation between defective PROS1 and venous thrombosis, and many patients with PSD have other factors influencing their Protein S levels. PROS1 is not associated with an increased risk of arterial thrombosis. www.hcplive.com/view/bendapu...

Progress for patients with Von Willebrand Disease (VWD) using a monoclonal antibody that targets Protein S www.biospace.com/press-releas... #ProteinS #VWD

High five to G Rouse (clinical assistant), J Pope (pharmacist), and R G Dalton (1954-2003, consultant haematologist) at Cheltenham General Hospital for their letter to the BMJ in 1996, recommending the introduction of 0.5mg warfarin tablets, and a score line making 0.25mg dosage possible. #warfarin

PSD affects: the pathways of “acute phase response”, “FXR/RXR activation”, “serotonin receptor signaling”, and “p70S6K signaling”, indicating interaction disorders among coagulation, inflammatory immune, and lipid metabolism. (page 4550) pubmed.ncbi.nlm.nih.gov/39265992/ #proteinsdeficiency

Sydney’s Story www.stoptheclot.org/patient-stor... #proteinsdeficiency #restinpeace

Protein S Deficiency (PSD) is a rare blood disorder that affects just a few thousand people worldwide. It is one of several known risk factors for thrombophilia and can increase the risk of blood clots such as Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). #proteinsdeficiency #thrombosis