@greg-knight.bsky.social
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Happy to have taken part in this cool project! It's really exciting to see the potential that protein design has in plant science!
add a skeleton here at some point
about 22 hours ago
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reposted by
3 days ago
Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible!
doi.org/10.64898/202...
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Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.
The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...
https://doi.org/10.64898/2026.07.10.737686
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