Nicola Maciocia (@nicolamaciocia.bsky.social)

Starting off my bluesky journey by sharing my paper published this week: CD21 targeted CAR-T cells for the treatment of T-ALL. The result of many years of work from many people. Funded by #CRUK #UKRI MRC and #GOSHCC www.science.org/doi/10.1126/...

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Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia Fratricide-resistant anti-CD21 CAR-T cells are effective in preclinical models of T cell acute lymphoblastic leukemia (T-ALL). https://www.science.org/doi/10.1126/scitranslmed.adr1476