Sangsoo Lee
@sangsoolee.bsky.social
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Research Associate at Johns Hopkins Neurology/Neuroscience Sleep, Circadian Rhythms, and more!
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It’s been a rewarding journey studying sleep as a postdoc, and I’m now exploring faculty positions in neuroscience. My latest work uncovers a neural mechanism for homeostatic sleep. Open to opportunities and always happy to chat! 🔗
linkedin.com/in/sang-soo-lee-55b395295
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https://linkedin.com/in/sang-soo-lee-55b395295
3 months ago
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The Wu Lab at @JohnsHopkins is looking for a new postdoc fellow to study sleep and/or circadian-related behaviors in mice. If you're interested in, please contact us.
www.markwulab.net
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Wu Lab
https://www.markwulab.net/
about 2 months ago
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reposted by
Sangsoo Lee
Seth Blackshaw
2 months ago
Our latest preprint is out, focusing on characterizing the response of Lhx6-positive neurons of the zona incerta (ZI) to naturally-occurring and experimentally-induced changes in the need to sleep, also known as sleep pressure.
www.biorxiv.org/content/10.1...
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Sleep pressure is differentially regulated by molecularly distinct subtypes of Lhx6-positive and Lhx6-negative neurons of the zona incerta
Sleep pressure, the accumulating drive towards sleep during wakefulness, is shaped by Lhx6-positive GABAergic neurons in the zona incerta (ZI). Here, we show that these neurons are broadly activated b...
https://www.biorxiv.org/content/10.1101/2025.07.30.667705v1
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A new paper from the Wu lab: "A subcircuit in the suprachiasmatic nucleus generates wakefulness", now published online in Advanced Science. Congrats all, in particular Qiang Liu!
advanced.onlinelibrary.wiley.com/doi/10.1002/...
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A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness
This study identifies a sub-circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub-circuit is labeled by the clock output molecule mWAKE, which suppresse...
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202505131
3 months ago
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It’s been a rewarding journey studying sleep as a postdoc, and I’m now exploring faculty positions in neuroscience. My latest work uncovers a neural mechanism for homeostatic sleep. Open to opportunities and always happy to chat! 🔗
linkedin.com/in/sang-soo-lee-55b395295
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https://linkedin.com/in/sang-soo-lee-55b395295
3 months ago
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I'm thrilled to share that my postdoctoral work is now published in
@science.org
. We uncovered a new circuit mechanism that regulates homeostatic sleep in mice. Huge thanks to all collaborators and supporters!
www.science.org/doi/10.1126/...
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Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep
Prolonged wakefulness leads to persistent, deep recovery sleep (RS). However, the neuronal circuits that mediate this process remain elusive. From a circuit screen in mice, we identified a group of th...
https://www.science.org/doi/10.1126/science.adm8203
4 months ago
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I'm excited to share my first post with some great news; our study on sleep homeostasis has been accepted! I’ll share more details once it’s published!
5 months ago
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Just moved! I’ll be posting updates about my research and scientific things here!
5 months ago
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