The diderm cell envelope is not a stack of layers but a unified scaffold of Inner Membrane–Peptidoglycan–Outer Membrane. We discuss how tethering the OM to the PG in E. coli preserves integrity — and extend the concept across diderm bacteria. Curr Opin Microbiol: doi.org/10.1016/j.mi... #microsky 🔬

Most stories don’t really start the way we write them in papers—and ours is no exception. To find out how it really began with a simple PCR trick, check out our Behind the Paper: « Out Of The Blue, It Came To Me » 👉 communities.springernature.com/posts/out-of... #MicroSky

#microsky We challenge the long-standing view that peptidoglycan alone protects cells from bursting. Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria. 📄 www.nature.com/articles/s41...