New in JNNP - the next chapter in the story of iatrogenic CAA 📕 and it really does seem to be different to sporadic CAA. Presence of deep haemorrhagic pathology in particular is unexpected but persistent signal. So what does this mean? … 1/2🧵 jnnp.bmj.com/content/earl...

It’s certainly the most comprehensive meta-analysis I’ve ever been involved with 🤓 TLDR: non-motor symptoms after stroke are common across domains and guess what? Not a great deal has changed in the last decade. A real wake up call to the field to address this huge unmet need ja.ma/3EMdegV

We tend to think of CAA-related inflammation as its own separate thing - but is this right? @AminaSellimi @UCLStrokeRes et al have found inflammation in people with prolonged TFNE (amyloid spells) - even though they all had "non-inflammatory" CAA... 1/2 onlinelibrary.wiley.com/doi/10.1002/...

Misty walk earlier today

We define CAA-ri by classical (asymmetrical, waxing/waning) white matter changes - this paper, new from the UCL Stroke Research Centre, describes imaging features of inflammation in CAA-ri that appear *before* these white matter changes ...1/2 www.neurology.org/doi/10.1212/...

Stretching my legs after an intense morning of writing