Does your imaging signal fade too fast? This is a common issue with in vivo imaging. FFz and CFz29 are next-generation substrates designed for bright, stable bioluminescent signals. Learn how these tools can support your in vivo imaging experiments: https://bit.ly/4pPyOnP

How does oxygen pressure reshape glucose metabolism in glioblastoma?  In the final post of our metabolism blog series, we explore how researchers used bioluminescent assays to track glucose uptake, lactate levels, and NAD(P)/NAD(P)H balance. https://bit.ly/4kB7F4i #MetabolismMadeSimple

We are excited to share our latest research with Longhorn Vaccines & Diagnostics. This collaboration demonstrates a biosafe, accessible workflow for detecting high-risk influenza A strains—including H5N1, H3N2 & H1N1—across veterinary & One Health settings. View the poster: https://bit.ly/4q44aXX

DNA takes time. mRNA delivers protein expression in hours—fast, uniform, and ideal for hard-to-transfect cells. Read the blog: https://bit.ly/4n9VP2T

Protein-protein interactions are fundamental cellular processes that affect how targets act in cells. This blog post has details and data. https://www.promegaconnections.com/measure-engagement-to-target-proteins-within-complexes-why-context-matters/

In a Nat. Comm. paper, researchers describe a BET protein degrader delivered via a CEACAM6-targeted ADC that significantly inhibited tumor growth in pancreatic cancer models. Read more: https://www.promega.com/en/resources/pubhub/research-highlights/research-summaries/2024/nakazawa-y-2024

qPCR can be a winding river.  Avoid the troubleshooting loop and choose GoTaq® Endure qPCR Master Mix: https://bit.ly/3XMKLOQ

Hoang et al describe use of BRET assays in primary mouse neuronal cultures, enabling real-time monitoring of GPCR activity in neuronal environments. More: https://www.promega.com/en/resources/pubhub/research-highlights/research-summaries/2024/hoang-htm-2024?utm_source=bluesky/ #PeerReviewedScience 🧪

MSI-H vs. MSS: What It Means for Tumor Biology. These tumors have intact mismatch repair & low mutational burden—impacting how they respond in immuno-oncology studies. Now new research with combination therapies is showing promise with MSS tumors. Learn more: https://bit.ly/4lDB3ax #MSS #pMMR #MMR

A study by Klein et al. explores how methylation modulates the regulation of microtubules during neuronal differentiation.  Read the summary: https://www.promega.com/en/resources/pubhub/research-highlights/research-summaries/2024/klein-p-2024 #PeerReviewedScience #CelebrateScience🧪

Maxwell®️ instruments continue to power labs worldwide. From research to crime and clinical labs, we help get results faster. Reliable nucleic acid purification has always been our thing and we’re just getting started. Learn what we can do together. #Maxwell20thCelebration  https://bit.ly/42X6lT5

Promega Research Scientist Rachel Ohana wrote an article for Lab Manager on the benefits of bioluminescence imaging and some key considerations for choosing the right instrument for your lab. https://www.labmanager.com/unlocking-cellular-insights-with-a-bioluminescence-imaging-system-34333

Diagnostics play a big role in keeping animals (and people) healthy. From poultry to pets to public health, molecular tools help track and respond to emerging threats like H5N1. Read the blog: https://bit.ly/4mgLy3P #AnimalHealth #OneHealth

Maxwell®️ instruments continue to power labs worldwide. From research to crime and clinical labs, we help get results faster. Reliable nucleic acid purification has always been our thing and we’re just getting started. Learn what we can do together. #Maxwell20thCelebration https://bit.ly/42X6lT5

Maxwell has been part of laboratory workflows for 20 years—and we’re just getting started. From research labs to high-throughput labs, if you need trusted nucleic acid extraction, try Maxwell. Explore Maxwell®️ Instruments. https://bit.ly/42X6lT5 #Maxwell20thCelebration #20YearsAndGoingStrong

Inconsistent Cq values? Flat curves?  Before you blame your primers, ask these 5 questions: https://bit.ly/4gnyHeM Featuring GoTaq® Endure.

In this blog, we highlight a HiBiT-based assay and live-cell imaging approach to visualize degradation of GSPT1, a common target in cancer research. Read it here: https://www.promegaconnections.com/a-new-view-of-protein-degradation-with-hibit-and-live-cell-imaging/#more-34436

Promega Research Scientist Marie Schwinn wrote an article for Biocompare on methods for studying PPIs within an endogenous context using live-cell assays. Read the article here: https://www.biocompare.com/Editorial-Articles/621221-Measuring-Endogenous-Protein-Interactions-in-Live-Cells/?arev=true

Cerebral organoids, real-time data. Learn how NanoLuc® and HaloTag® tools reveal cell identity, protein expression and tissue development without compromising the model.  Our new white paper shows how to design assays that deliver meaningful, long-term data from 3D models: https://bit.ly/4mYrch3

🧪Biologics are evolving fast—from ADCs to cell therapies. Promega scientists share how innovative bioassays are shaping the future of drug development. Read more: https://www.promegaconnections.com/at-the-forefront-of-biologics-characterization-insights-from-promega-rd-scientists/

Viability qPCR filters out DNA from dead bacteria—so you only act on live threats like viable Legionella. Faster decisions. Fewer false positives. Read the Blog: https://bit.ly/4n5GZe4 #WaterSafety #Legionella

Glycogen is a key energy reserve that fuels cells during stress, fasting, and recovery. In our next metabolism blog, we explore its role in energy metabolism, disease, and performance using human biology as a model. Learn how to measure glycogen: https://bit.ly/40JMKom #MetabolismMadeSimple

Valto Biocontrol moved from outsourcing to in-house processing of 20,000 plant samples using our Maxwell® HT simplyRNA Kit on their high-throughput robot. Our Field Support Scientist team made the transition seamless. Learn more: https://bit.ly/4kaw2p9 #Maxwell20thCelebration

🧪NanoBRET® Target Engagement assays are a great alternative to mass spec-based cell selectivity approaches. This blog explains why. https://www.promegaconnections.com/cellular-selectivity-profiling-unveiling-novel-interactions-and-more-accurate-compound-specificity/

Learn about our new partnership to license a novel engineered reverse transcriptase that delivers enhanced accuracy and sensitivity in RNA analysis. 

Targeted protein degradation is a promising approach for targeting disease-causing proteins once considered “undruggable.” Read this article to learn about this emerging field. https://www.biospectrumasia.com/analysis/25/26567/unlocking-the-undruggable-with-targeted-protein-degradation.html

MSI-H tumors exhibit high mutation rates—making MSI a valuable biomarker in immuno-oncology research because it’s closely tied to neoantigen load and immune checkpoint response. Explore how MSI status is shaping research in immuno-oncology and therapeutic stratification: https://bit.ly/4mjfLzD

🧪Incorporating live-cell kinetic analysis helps answer questions about how fast, how thoroughly and how sustainably a degrader works. Learn more in this blog post: https://www.promegaconnections.com/unlocking-the-power-of-live-cell-kinetics-in-degrader-development/

🧪Discover how the OceanOmics Centre uses the Maxwell® RSC 48 to scale marine eDNA monitoring with greater speed, consistency, and confidence. #Maxwell20thCelebration https://www.promegaconnections.com/how-the-oceanomics-centre-is-using-the-maxwell-rsc-to-scale-edna-biodiversity-monitoring/

What if you could observe your NanoLuc® assay results in real time?  With the GloMax® Galaxy Bioluminescence Imager, researchers can image β-catenin nuclear translocation in individual cells, validating spatial and kinetic pathway responses.  See how in our blog: https://bit.ly/3Hm6Oqm

Studying the genetics of Type 2 diabetes means processing thousands of blood samples. Researchers at Oxford used Maxwell® Instruments to automate extraction and keep their large-scale study moving. Learn more: https://bit.ly/4k7eDO8 #Maxwell20thCelebration

The 36th International Symposium on Human Identification (ISHI) keynote session will explore the use of AI for deeper insights in forensic profiling. Learn more here: https://www.promega.com/aboutus/press-releases/global/2025/august-19-2025-36th-international-symposium-on-human-identification-ishi/

🧪Learn how molecular glues derived from thalidomide can work with protein degradation machinery to reach undruggable targets. Read the blog. https://www.promegaconnections.com/how-thalidomide-and-molecular-glue-are-rede%ef%ac%81ning-drug-discovery/

Measuring cell proliferation is critical to many projects, but finding the right assay can be tough. Learn about the advantages of protein markers for analysis in 2D and 3D systems. https://www.biocompare.com/Editorial-Articles/620667-Using-Protein-Markers-to-Study-Cell-Proliferation-in-2D-and-3D/

Spheroids or organoids? Choosing the best 3D model is just the start. If you're working with complex cultures, Janelia Fluor® HaloTag® Ligands can offer brighter signals and superior photostability for time course experiments. Learn how to image live 3D models with confidence: https://bit.ly/3JjlerU

Does your research need efficient, reliable nucleic acid extraction? A Maxwell® Instrument could be the answer. These trusted instruments offer high-quality nucleic acid extraction with minimal hands-on effort— no assembly required. Find your Maxwell: https://bit.ly/4lJztV9 #Maxwell20thCelebration

In the latest article at Drug Discovery News, Promega Research Scientist Kristin Riching shares her thoughts about the importance of degrader kinetics and technologies to help optimize degrader efficacy. https://www.drugdiscoverynews.com/capturing-degrader-efficacy-through-live-cell-kinetics-16562

Malate is essential for ATP production, redox balance, and amino acid synthesis. In our next metabolism blog, we explore its role in energy metabolism and uncover some of its connections to human disease. Read more about malate and how it's measured: https://bit.ly/44YqWYz #MetabolismMadeSimple

🧬 MSI-H isn't just a marker of tumor instability—it can indicate an underlying hereditary lifetime risk of developing certain cancers, especially those associated with Lynch syndrome. This makes it a key piece in understanding cancer genomics.  Learn more: https://bit.ly/46vNcKM #MSI #Oncology #MSIH

🧪There’s a new fav target for NanoBRET® Target Engagement Assays. Learn about helicases and how to measure their activity inside live cells. See blog for details. https://www.promegaconnections.com/atp-powered-proteins-beyond-kinases-and-why-helicases-are-stealing-the-spotlight/

Understanding your experimental goals is key to choosing the right luciferase reporter assay. Learn how to match reporter type, detection chemistry, and assay format in our latest blog post: https://www.promegaconnections.com/matching-luciferase-reporter-assays-to-your-experimental-goals/

GoTaq® Endure powers through the tough stuff—so you don’t waste time on repeat runs.  Pair it with XpressAmp™ for a 3-step workflow that skips RNA purification but still delivers clean, reliable amplification.  Inhibitor-tolerant. Multiplex-ready. Stress-free.  Learn more: https://bit.ly/3XMKLOQ

🧪Learn how HiBiT®️-based NanoBRET®️ assays, paired with live-cell imaging on the GloMax®️ Galaxy Imager, offer a streamlined approach for studying peptide–GPCR interactions in live cells. https://www.promegaconnections.com/hibit-based-nanobret-assay-sheds-light-on-gpcr-ligand-binding-in-live-cells/

Ever wish you could see protein:protein interactions occur in real time—clearly, cleanly and in living cells? With our NanoLuc® bioluminescence technology and GloMax® Galaxy Bioluminescence Imager, now you can.  See how we’re helping researchers visualize protein dynamics: https://bit.ly/4fafFrK

Promega has committed to set near-term company-wide greenhouse gas emissions with Science Based Targets initiative. Learn more in our latest press release: https://www.promega.com/aboutus/press-releases/global/2025/july-30-2025-promega-corporation-commits-to-science-based-targets-initiative/

Bright, stable and versatile, NanoLuc® luciferase powers a wide range of bioluminescent assays, from protein interactions to real-time imaging. Learn how this engineered enzyme can bring sensitivity and flexibility to your next experiment: https://bit.ly/4kVOQcf

Understanding the differences between MSI by PCR, MSI by NGS and dMMR by IHC is key to choosing the right approach. Learn more about these topics and earn continuing education credits, read our educational article focused on MSI testing and the MSI-H biomarker: https://bit.ly/4o9w9EF

Which immunoassay is right for you? In the latest editorial from Biocompare, Promega Research Scientist Hicham Zegzouti shares some tips for making the best decision for your project. https://www.biocompare.com/Editorial-Articles/619803-Important-Considerations-for-Immunoassay-Selection/

Christina Sholar’s lab at DCi was the first to purchase a Maxwell®️ instrument when it launched in 2005. Today, the lab uses three of the latest model. Read how Maxwell®️ instruments support their workflow analyzing samples for organ transplants. https://www.promegaconnections.com/dci-maxwell-2025/

Struggling with exosome isolation? Check out the latest Biocompare editorial to learn about overcoming these challenges by combining INOVIQ’s EXO-NET®️ technology and Maxwell®️ purification chemistry. https://www.biocompare.com/Editorial-Articles/619659-Overcoming-Challenges-in-Exosome-Research/