Fresh from #ASCO2025 meetings.asco.org/abstracts-pr... SBRT vs microwave ablation (MWA) in pts with CRC liver oligo-mets ➡️ n=100, n=92 treated (39 SBRT, 53 MWA) ➡️ 18/92 pts (20%) reported side effects ➡️ n=3 G3-4 pain; n=2 infections after open MWA, n=1 bowelperforation after percutaneous MWA

Neoadjuvant chemo-IO for Borderline Resectable & Unresectable Stage III NSCLC Conclusion of authors: "high rates of surgical resectability" Pts with completed surgery: III A: 65/79 - 82% III B: 16/27 - 59% III C: 3/6 - 50% -> careful interpretation needed jamanetwork.com/journals/jam...

🔥 SAVE THE DATE 🔥 ❓ What is the population-health effect of novel anti-cancer drugs ❓ How do anti-cancer drugs compare to other drugs and health services ❓ How to improve sustainability of cancer care and medicine in the future Virtual Grand Rounds in Radiation Oncology www.usz.ch/veranstaltun...

Thought provoking ! Population-health impact of new drugs recommended by NICE in England during 2000–20 - quality-adjusted life-years and incremental cost-effectiveness ratio used for analysis 👉 overall NEGATIVE (!) cumulative impact 👉 data for #radonc ? www.thelancet.com/journals/lan...

Retrospective multicenter study of SBRT for pulmonary oligometastatic HNSCC - 16 centers, 178 pts, 284 pulmonary mets - 1a local failure rate 5.5% - no grade 4/5 toxicities 👉 supporting prospective evaluation, in preparation by EORTC & P Balermpas www.redjournal.org/article/S036...

Aiming to refine your #radonc in 2025 ! Offer RT for low-volume metastatic PC, only ? What benefit of RT is to be communicated to pts & colleagues ? How about SBRT or surgery ? Virtual Grand Rounds in Radiation Oncology Jan 8th / 17:00 - 17:30 CET Dr Alberto Bossi 👇 www.usz.ch/veranstaltun...

Virtual Grand Rounds in Radiation Oncology Let`s start 2025 with another highly-important lecture Jan 8th 2025 - 17:00 - 17:30 Dr. Alberto Bossi Radiotherapy of the primary in metastatic prostate cancer - insights from PEACE-1 Link 👇 www.usz.ch/veranstaltun...

Season's Greetings

Safe practice of spine SBRT requires high-quality data about SC dose tolerance - Cohort study 2051 pts - 30 cases of RM, 19 of which G3 to G4 - 2a rate of G1-4 RM 1.8% - cord dose D0.1cc of 19.1Gy / Dmax of 20.8Gy = 1.0% risk of G3 to G4 RM at 2 years jamanetwork.com/journals/jam...

Todas is HCC day! - RTOG 1112 - HCC unsuitable for or refractory to local-regional Tx (n=177) - SBRT & Sorafenib vs Sorafenib - After adjustment for stratification factors, improved OS after SBRT (HR 0.72) - Median PFS improved from 5.5 to 9.2 mo (HR 0.55) jamanetwork.com/journals/jam...

And yet another prospective trial confirming excellent efficacy of SBRT for localized HCC - n=36 pts - median tumor size 2.3 cm - median FU 49 mo - 3-year local control rate 93% - Grade 3 AE 11% www.redjournal.org/article/S036...

Randomized comparison of SBRT vs RFA for recurrent small HCC (n=166 pts) 👆 Freedom from local progression significantly improved after SBRT: 2a 92.7% vs 75.8%, HR=0.45 ! 👉 No difference in PFS (median 37.6 vs 27.6mo) and OS (2a 97.6% vs 93.9%) 👍 ascopubs.org/doi/10.1200/...

Remember the misleading press about "brutal" #radonc after PROSPECT ? This is what modern RT can achieve for elderly breast cancer patients ! 👉 "Endocrine Tx was associated with a greater reduction in HRQOL compared with RT at 24 mo" 👉 oncological data awaited www.thelancet.com/journals/lan...

ESTRO power team ! Anna Kirby and Barbara Jereczek-Fossa as past-president and president-elect Thanks you so much for your 💪 collaboration, friendship and dedication, to 👉 advance multidisciplinary cancer care 👉 elevate radiation oncology 👉 develop ESTRO society

Radiation Oncology is characterized by rapid innovation Dissemination & implementation are important aspects to bring this progress to our cancer patients in daily practice Well written review by Erin Gillespie and colleagues 👇 www.redjournal.org/article/S036...

In case you may have missed any of the Virtual Grand Rounds in Radiation Oncology lectures Recordings are 👇 youtube.com/playlist?lis... Endorsed by: ESTRO DEGRO SASRO

Virtual Grand Rounds in Radiation Oncology „Revving Up Gastric Cancer Care: Insights from the TOPGEAR Trial” Presented by Prof. Karin Haustermans December 4th 17:00 – 17:30 Link to online meeting 👇 www.usz.ch/veranstaltun... Endorsed by: ESTRO DEGRO SASRO

ESTRO Scientific Council Meeting in Brussels Hopefully in brighter colors than todays sky …

ETH Zürich Polyball Zwischen Göttern und Menschen Preparations almost finished

PEACE-1 trial of prostate radiotherapy in mHSPC. Improvement in rPFS when used in addition to ADT and abiraterone. Medsky. Oncsky.

PEACE-1 published Radiotherapy of the prostate in metastatic pts prevents serious GU complications, in pts with low and high tumor burden How to select patients? - all ? - based on live expectancy ? - response to systemic Tx ? - prostate volume ? www.thelancet.com/journals/lan...

Curious about #RadiationOncology on BlueSky Warm welcome to all colleagues and friends !