Prashant Sharma
@prashantpsharma.bsky.social
📤 103
đź“Ą 52
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Invertebrate biology. Phylogenomics. Whole genome duplications. Comparative development. Lab head.
Lab alum and Harvard postdoc Guilherme Gainett delivers the first gene edited horseshoe crabs!!
www.mbl.edu/news/whitman...
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Whitman Fellow Designs Genomic Tools to Study Horseshoe Crab Eye Development | Marine Biological Laboratory
They may be famous for their striking blue blood, but horseshoe crabs have an award-winning vision system.  In the 1930s, Haldan Keffer Hartline produced the first single-cell recording of a photorec...
https://www.mbl.edu/news/whitman-fellow-designs-genomic-tools-study-horseshoe-crab-eye-development
2 months ago
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medienportal.univie.ac.at/en/media/rec...
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What the sea spider genome reveals about their bizarre anatomy
The first high-quality pycnogonid genome provides novel insights in chelicerate evo-devo
https://medienportal.univie.ac.at/en/media/recent-press-releases/detailansicht-en/artikel/what-the-sea-spider-genome-reveals-about-their-bizarre-anatomy/
3 months ago
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The lab is proud to have contributed to the first chromosome-level sea spider genome! Many thanks to Niko Papadopoulos, Georg Brenneis, and Andi Wanninger, who spearheaded the work!
#pycnogonida
bmcbiol.biomedcentral.com/articles/10....
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The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with a reduced posterior tagma - BMC Biology
Background Chelicerate evolution is contentiously debated, with recent studies challenging traditional phylogenetic hypotheses and scenarios of major evolutionary events, like terrestrialization. Sea ...
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02276-x
3 months ago
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It’s an honor to have taught the arthropod module at Woods Hole Embryology! I started my daddy-long legs system at Woods Hole as a student when I took the course 16 years ago. What fun to be invited back to teach students to inject spiders and arachnid embryos! Added bonus: Gui Gainett and Limulus!
4 months ago
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www.sciencedirect.com/science/arti...
The lab is delighted to release the first comparative analysis of the arachnid orders Opiliones and Solifugae, using chromosome-level genomes! We look at macrosynteny as a phylogenetic character for resolving chelicerate phylogeny.
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Exploring genome architecture as a source of phylogenetic characters for resolving the apulmonate arachnid polytomy
Chromosome-level genome assemblies are powerful tools for identifying the presence of rare genomic changes that can overcome phylogenetically intracta…
https://www.sciencedirect.com/science/article/abs/pii/S1055790325000971
4 months ago
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A new review paper from the lab—fun times with sea spider and daddy-long legs embryos!
www.sciencedirect.com/science/arti...
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Evolution and homology of leg segments in Chelicerata: Evo-devo solutions to century-old challenges
A major theme in the evolution of Arthropoda is the origin and diversification of jointed appendages. One appealing framework for the evolution of art…
https://www.sciencedirect.com/science/article/pii/S1467803925000386?dgcid=author
5 months ago
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reposted by
Prashant Sharma
Vincent Pasque
6 months ago
Excited to share our recent review on extraembryonic mesoderm development, just published in Development! "Extra embryonic mesoderm during development and in in vitro models."
journals.biologists.com/dev/article/...
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Prashant Sharma
MultiplEye Lab
6 months ago
📢New paper in
@royalsociety.org
Proceedings B!📢 We tracked
#eye
#development
in seven spider species with wildly different visual systems to try and identify the mechanisms underlying their diversity 👀👀👀👀 1/n
royalsocietypublishing.org/doi/10.1098/...
(Funded by
@leverhulme.bsky.social
)
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Development and patterning of a highly versatile visual system in spiders | Proceedings of the Royal Society B: Biological Sciences
Visual systems provide a key interface between organisms and their surroundings, and have evolved in many forms to perform diverse functions across the animal kingdom. Spiders exhibit a range of visual abilities and ecologies, the diversity of which is ...
https://royalsocietypublishing.org/doi/10.1098/rspb.2024.2069
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“Just because something's important, doesn't mean it's not very small.” —Frank the Pug, 1997
7 months ago
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reposted by
Prashant Sharma
Alex McDougall
7 months ago
Microtubules still doing their thing in an early ascidian embryo (Phallusia). Thanks to the Ascidian BioCell Team
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Friday is Phalangium day!
7 months ago
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reposted by
Prashant Sharma
Alex McDougall
7 months ago
marine embryo (ascidian/Phallusia) making a gut (gastrulation)...thanks to the Ascidian BioCell Team. Cell contours are blue, microtubules that separate the chromosomes are magenta
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Interested in rare genomic changes and arachnid phylogeny? Check out our preprint here! We’re taking a look at the architecture of Solifugae and Opiliones genomes.
papers.ssrn.com/sol3/papers....
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Exploring Genome Architecture as a Source of Phylogenetic Characters for Resolving the Apulmonate Arachnid Polytomy
Chromosome-level genome assemblies are powerful tools for identifying the presence of rare genomic changes that can overcome phylogenetically intractable proble
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5147386
7 months ago
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The lab was delighted to host Professor Eileen Hebets, the John T. Emlen lecturer this year! For more on her fantastic work on spider songs and dances, please visit
hebetslab.unl.edu
.
7 months ago
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The lab is delighted to release the first genome for the giant American vinegaroon! The slowly-evolving order Uropygi captures the strongest signature yet of the arachnopulmonate whole genome duplication.
#biodiversity
#genomics
academic.oup.com/jhered/advan...
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A chromosome-level genome of the giant vinegaroon Mastigoproctus giganteus exhibits the signature of pre-Silurian whole genome duplication
Abstract. Within the arachnids, chromosome-level genome assemblies have greatly accelerated the understanding of gene family evolution and developmental ge
https://academic.oup.com/jhered/advance-article/doi/10.1093/jhered/esae074/7925303
8 months ago
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If you’re ever feeling down, Anoplodactylus has your back.
8 months ago
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Very excited about the publication of this review with my dear friend and colleague, Efrat Gavish-Regev!
www.annualreviews.org/content/jour...
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The Evolutionary Biology of Chelicerata | Annual Reviews
Chelicerata constitutes an ancient, biodiverse, and ecologically significant group of Arthropoda. The study of chelicerate evolution has undergone a renaissance in the past decade, resulting in major ...
https://www.annualreviews.org/content/journals/10.1146/annurev-ento-022024-011250
8 months ago
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A scorpion embryo to brighten your day. Purple: Pax2A. Yellow: Pax2B. Blue: nuclei.
8 months ago
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I’m mesmerized by Japanese sea nettles.
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8 months ago
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reposted by
Prashant Sharma
Gabriele Uhl
9 months ago
doi.org/10.1073/pnas...
Olfaction in spiders. We found that the wall pore sensilla in spiders look similar from the outside to those of insects, but differ ultrastructurally in various ways. Independent evolution! 🧪
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Olfaction with legs—Spiders use wall-pore sensilla for pheromone detection | PNAS
The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insec...
https://doi.org/10.1073/pnas.2415468121
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reposted by
Prashant Sharma
Stowers Institute
8 months ago
Let's take a look
#UnderTheScope
! 👀 🔬 This is an adult Nematostella where stinging cells are labeled with eGFP (green). The Gibson Lab studies these to understand
#evolution
. (
@gelatinoussting.bsky.social
)
#EvoDevo
#CellBiology
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