Prashant Sharma
@prashantpsharma.bsky.social
📤 112
đź“Ą 53
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Invertebrate biology. Phylogenomics. Whole genome duplications. Comparative development. Lab head.
Lab alum and Harvard postdoc Guilherme Gainett delivers the first gene edited horseshoe crabs!!
www.mbl.edu/news/whitman...
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Whitman Fellow Designs Genomic Tools to Study Horseshoe Crab Eye Development | Marine Biological Laboratory
They may be famous for their striking blue blood, but horseshoe crabs have an award-winning vision system.  In the 1930s, Haldan Keffer Hartline produced the first single-cell recording of a photorec...
https://www.mbl.edu/news/whitman-fellow-designs-genomic-tools-study-horseshoe-crab-eye-development
6 months ago
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medienportal.univie.ac.at/en/media/rec...
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What the sea spider genome reveals about their bizarre anatomy
The first high-quality pycnogonid genome provides novel insights in chelicerate evo-devo
https://medienportal.univie.ac.at/en/media/recent-press-releases/detailansicht-en/artikel/what-the-sea-spider-genome-reveals-about-their-bizarre-anatomy/
7 months ago
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The lab is proud to have contributed to the first chromosome-level sea spider genome! Many thanks to Niko Papadopoulos, Georg Brenneis, and Andi Wanninger, who spearheaded the work!
#pycnogonida
bmcbiol.biomedcentral.com/articles/10....
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The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with a reduced posterior tagma - BMC Biology
Background Chelicerate evolution is contentiously debated, with recent studies challenging traditional phylogenetic hypotheses and scenarios of major evolutionary events, like terrestrialization. Sea ...
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02276-x
7 months ago
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It’s an honor to have taught the arthropod module at Woods Hole Embryology! I started my daddy-long legs system at Woods Hole as a student when I took the course 16 years ago. What fun to be invited back to teach students to inject spiders and arachnid embryos! Added bonus: Gui Gainett and Limulus!
8 months ago
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www.sciencedirect.com/science/arti...
The lab is delighted to release the first comparative analysis of the arachnid orders Opiliones and Solifugae, using chromosome-level genomes! We look at macrosynteny as a phylogenetic character for resolving chelicerate phylogeny.
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Exploring genome architecture as a source of phylogenetic characters for resolving the apulmonate arachnid polytomy
Chromosome-level genome assemblies are powerful tools for identifying the presence of rare genomic changes that can overcome phylogenetically intracta…
https://www.sciencedirect.com/science/article/abs/pii/S1055790325000971
8 months ago
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A new review paper from the lab—fun times with sea spider and daddy-long legs embryos!
www.sciencedirect.com/science/arti...
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Evolution and homology of leg segments in Chelicerata: Evo-devo solutions to century-old challenges
A major theme in the evolution of Arthropoda is the origin and diversification of jointed appendages. One appealing framework for the evolution of art…
https://www.sciencedirect.com/science/article/pii/S1467803925000386?dgcid=author
9 months ago
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reposted by
Prashant Sharma
Vincent Pasque
10 months ago
Excited to share our recent review on extraembryonic mesoderm development, just published in Development! "Extra embryonic mesoderm during development and in in vitro models."
journals.biologists.com/dev/article/...
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reposted by
Prashant Sharma
MultiplEye Lab
10 months ago
📢New paper in
@royalsociety.org
Proceedings B!📢 We tracked
#eye
#development
in seven spider species with wildly different visual systems to try and identify the mechanisms underlying their diversity 👀👀👀👀 1/n
royalsocietypublishing.org/doi/10.1098/...
(Funded by
@leverhulme.bsky.social
)
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Development and patterning of a highly versatile visual system in spiders | Proceedings of the Royal Society B: Biological Sciences
Visual systems provide a key interface between organisms and their surroundings, and have evolved in many forms to perform diverse functions across the animal kingdom. Spiders exhibit a range of visual abilities and ecologies, the diversity of which is ...
https://royalsocietypublishing.org/doi/10.1098/rspb.2024.2069
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“Just because something's important, doesn't mean it's not very small.” —Frank the Pug, 1997
11 months ago
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reposted by
Prashant Sharma
Alex McDougall
11 months ago
Microtubules still doing their thing in an early ascidian embryo (Phallusia). Thanks to the Ascidian BioCell Team
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Friday is Phalangium day!
11 months ago
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reposted by
Prashant Sharma
Alex McDougall
11 months ago
marine embryo (ascidian/Phallusia) making a gut (gastrulation)...thanks to the Ascidian BioCell Team. Cell contours are blue, microtubules that separate the chromosomes are magenta
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Interested in rare genomic changes and arachnid phylogeny? Check out our preprint here! We’re taking a look at the architecture of Solifugae and Opiliones genomes.
papers.ssrn.com/sol3/papers....
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Exploring Genome Architecture as a Source of Phylogenetic Characters for Resolving the Apulmonate Arachnid Polytomy
Chromosome-level genome assemblies are powerful tools for identifying the presence of rare genomic changes that can overcome phylogenetically intractable proble
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5147386
11 months ago
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The lab was delighted to host Professor Eileen Hebets, the John T. Emlen lecturer this year! For more on her fantastic work on spider songs and dances, please visit
hebetslab.unl.edu
.
11 months ago
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The lab is delighted to release the first genome for the giant American vinegaroon! The slowly-evolving order Uropygi captures the strongest signature yet of the arachnopulmonate whole genome duplication.
#biodiversity
#genomics
academic.oup.com/jhered/advan...
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A chromosome-level genome of the giant vinegaroon Mastigoproctus giganteus exhibits the signature of pre-Silurian whole genome duplication
Abstract. Within the arachnids, chromosome-level genome assemblies have greatly accelerated the understanding of gene family evolution and developmental ge
https://academic.oup.com/jhered/advance-article/doi/10.1093/jhered/esae074/7925303
12 months ago
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If you’re ever feeling down, Anoplodactylus has your back.
12 months ago
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Very excited about the publication of this review with my dear friend and colleague, Efrat Gavish-Regev!
www.annualreviews.org/content/jour...
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The Evolutionary Biology of Chelicerata | Annual Reviews
Chelicerata constitutes an ancient, biodiverse, and ecologically significant group of Arthropoda. The study of chelicerate evolution has undergone a renaissance in the past decade, resulting in major ...
https://www.annualreviews.org/content/journals/10.1146/annurev-ento-022024-011250
12 months ago
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A scorpion embryo to brighten your day. Purple: Pax2A. Yellow: Pax2B. Blue: nuclei.
12 months ago
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I’m mesmerized by Japanese sea nettles.
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12 months ago
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reposted by
Prashant Sharma
Gabriele Uhl
about 1 year ago
doi.org/10.1073/pnas...
Olfaction in spiders. We found that the wall pore sensilla in spiders look similar from the outside to those of insects, but differ ultrastructurally in various ways. Independent evolution! 🧪
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Olfaction with legs—Spiders use wall-pore sensilla for pheromone detection | PNAS
The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insec...
https://doi.org/10.1073/pnas.2415468121
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reposted by
Prashant Sharma
Stowers Institute
12 months ago
Let's take a look
#UnderTheScope
! 👀 🔬 This is an adult Nematostella where stinging cells are labeled with eGFP (green). The Gibson Lab studies these to understand
#evolution
. (
@gelatinoussting.bsky.social
)
#EvoDevo
#CellBiology
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