An interferon-stimulated genes signature including IFI27 and OAS1, together with complement levels, may reflect the immune state of patients with SLE and identify active disease. www.renalandurologynews.com/news/sle-lup...

In a phase 1b-2 trial, neoadjuvant disitamab vedotin plus tislelizumab shows preliminary efficacy and acceptable toxicity in HER2-expressing muscle-invasive bladder cancer -- and may enable bladder-sparing treatment. www.renalandurologynews.com/reports/mibc... #EAU26

CAIX-PET had “optimal sensitivity” for detecting ccRCC in patients with VHL disease, and found more renal lesions than MRI, as well as some central nervous system tumors. www.renalandurologynews.com/reports/ccrc... #EAU26

Adding radiation therapy or surgery to the primary tumor does not improve progression-free survival in men already receiving best systemic therapy for de novo metastatic prostate cancer, a phase 2 trial finds. www.renalandurologynews.com/news/cytored...

Progress is being made in addressing long-standing racial inequities in kidney transplantation. Read our latest feature: www.renalandurologynews.com/features/kid...

Extraprostatic extension or seminal vesicle invasion detected on preoperative MRI were independently associated with biochemical recurrence and metastatic failure. www.renalandurologynews.com/news/prostat...

Among men with cribriform-positive disease at radical prostatectomy, only those with grade group 3 or higher disease or pT3b likely need adjuvant or early salvage treatment. www.renalandurologynews.com/news/cribrif...

In a randomized trial, half of patients who received TULSA maintained both pad-free continence and erections at 6 months compared with one-quarter who had RP. www.renalandurologynews.com/news/prostat... #prostatecancer

In a phase 3 trial of high-risk IgA nephropathy, iptacopan halved the rate of annual eGFR decline over 24 months compared with placebo. www.renalandurologynews.com/news/iga-nep...

Addressing B-vitamins status in patients with CKD may seem minor. Yet it is an important aspect of CKD care. Read our latest feature: www.renalandurologynews.com/features/b-v...

In children undergoing ESWL, adjunctive α1-blocker therapy enhances the stone-free rate and reduces the stone expulsion time. www.renalandurologynews.com/news/stones-...

The difficulty of sustaining high fluid intake may contribute to persistent stone recurrence rates. www.renalandurologynews.com/news/fluid-i...

PSMA PET-based (PPP3) nomograms outperform conventional risk scoring in determining overall survival over 3, 5, and 7 years across the prostate cancer spectrum. www.renalandurologynews.com/news/prostat...

The presence of the M1 variant may identify patients whose chronic kidney disease (CKD) has a different etiology not attributable to the APOL1 high-risk genotype. www.renalandurologynews.com/news/m1-vari...

Drs. Rainjade Chung, Benjamin Croll, and Robert Uzzo share 6 of the most compelling study findings from the ASCO GU Cancers Symposium. Read our latest editorial: www.renalandurologynews.com/features/asc... #NationalKidneyMonth #WorldKidneyDay

A single PSA test at midlife may identify men with a low risk of prostate cancer for up to 20 years, supporting longer screening intervals. www.renalandurologynews.com/news/prostat...

Phosphorus management has long been a cornerstone of care for patients with chronic kidney disease and end-stage kidney disease. Read our latest feature: www.renalandurologynews.com/features/pho...

The electronic device was successfully implanted and activated in 6 men with SUI who experienced reduction in pad usage over 1 year. www.renalandurologynews.com/news/stress-...

In patients undergoing RP with adjuvant radiation, PLND showed no survival benefit, regardless of prostate cancer risk group or number of lymph nodes removed. www.renalandurologynews.com/news/plnd-su...

Switching to sirolimus significantly reduces the risk of subsequent cSCC in high-risk kidney transplant recipients with history of the skin cancer. www.renalandurologynews.com/news/sirolim...

This meta-analysis of 7 trials provides the highest level of evidence to date supporting MDT for selected patients with oligometastatic prostate cancer. www.renalandurologynews.com/news/prostat... #prostatecancer

Although cancer survivors with high-deductible health plans technically have insurance coverage, they have increased risks for poor survival. www.renalandurologynews.com/news/cancer-...

Active surveillance is noninferior to BCG induction therapy for invasive relapse-free survival in patients with high-grade T1 bladder cancer with no residual tumor on second TURBT. www.renalandurologynews.com/news/bladder... #bladdercancer

Treatment guidelines for severe hyponatremia should be reexamined to allow for faster sodium correction. www.renalandurologynews.com/news/faster-...

Preoperative MRI, specifically 9-b-value DWI and T1-mapping, helps predict if a patient will develop stage 3 CKD after partial or radical nephrectomy for kidney cancer. www.renalandurologynews.com/news/ckd-mri... #kidneydisease

Bipolar enucleation significantly reduced IPSS in men with large prostates and obstructed bladder necks, but the procedure led to a high rate of retrograde ejaculation. www.renalandurologynews.com/news/benign-...

An early clinical trial is suggesting that directly injecting an immune-activating compound into prostate tumors before surgery is safe and may help the innate and adaptive immune system recognize and attack cancer cells. Read our latest feature: www.renalandurologynews.com/features/aut...

In a real-world study, minimally invasive surgical treatments such as Rezūm and PUL were associated with higher rates of retreatment and medication reinitiation compared with TURP. Findings may inform expectations regarding treatment durability. www.renalandurologynews.com/news/benign-...

Pathologic concordance between prostate biopsy and radical prostatectomy improves with use of a novel robotic-assisted transperineal fusion biopsy platform. Optimization of risk stratification at prostate biopsy has implications for focal therapy use. www.renalandurologynews.com/news/prostat...

Most men with post-procedural stress urinary incontinence in a prospective study achieved at least halving of pad use within 12 months. www.renalandurologynews.com/news/artific...

In a randomized trial of men with a single suspicious lesion on MRI, targeted perilesional biopsy matched standard targeted and systematic biopsy for detecting clinically significant prostate cancer -- with fewer complications. www.renalandurologynews.com/news/prostat... #prostatecancer

The American Urological Association (AUA) has issued a new guideline on the surgical management of kidney and ureteral stones in a 3-part series published in The Journal of Urology. Read our latest feature: www.renalandurologynews.com/features/aua...

Based on EMBARK data, both enzalutamide monotherapy and combination therapy (with leuprolide) reduced the likelihood of distant metastasis in patients with high-risk biochemically recurrent prostate cancer. www.renalandurologynews.com/news/high-ri... #prostatecancer

The PLCO model may improve prediction of prostate cancer death at the point of screening. The Stockholm3 test may improve screening itself. www.renalandurologynews.com/news/prostat... #prostatecancer

Discomfort with death relates to a number of challenging situations and resulting ethical dilemmas, some of which may originate from unspoken or inadequately articulated goals of care. Read our latest feature: www.renalandurologynews.com/features/end...

In a randomized trial, FANS f-URS and mini-PCNL had comparable immediate stone clearance rates. www.renalandurologynews.com/news/kidney-... #kidneystones

Cribriform carcinoma and/or intraductal carcinoma on prostate histopathology was associated with higher rates of metastasis. www.renalandurologynews.com/news/cribrif... #prostatecancer

While patients with multiple risk factors for kidney stones may receive broad, generalized advice, preventing recurrence requires precision and an individualized plan. Read our latest feature: www.renalandurologynews.com/features/rec... #kidneystones

Patients with CKD are among those at increased risk for West Nile neuroinvasive disease and have nearly twice the risk of dying from the disease. www.renalandurologynews.com/news/chronic... #kidneydisease

Persistent hematuria in patients diagnosed with lupus nephritis independently predicts adverse outcomes. www.renalandurologynews.com/news/hematur... #lupus

Multimodal treatment including radical prostatectomy might lead to improved survival in patients with oligometastatic prostate cancer treated with ADT. www.renalandurologynews.com/reports/pros... #SUO2025 #prostatecancer

Among real-world US patients with mCSPC, apalutamide users achieved PSA90 response approximately 5 months earlier than abiraterone users, with more achieving deeper PSA decline. www.renalandurologynews.com/reports/psa-... #SUO2025 #prostatecancer

Overall survival is no better for patients diagnosed with NMIBC who progress directly to metastasis. www.renalandurologynews.com/reports/non-... #SUO2025 #bladdercancer

Cytoreductive nephrectomy merits further consideration in appropriately risk-stratified, surgically fit patients with mRCC. www.renalandurologynews.com/reports/cyto... #SUO2025 #kidneycancer

A combined PSMA-PET/MRI scanner better detected clinically significant prostate cancer in men on active surveillance. www.renalandurologynews.com/reports/pros... #SUO2025 #prostatecancer

Increases in variant histology bladder cancer in the US highlight the importance of precision in pathologic review of biopsy specimens. www.renalandurologynews.com/reports/vari... #SUO2025 #bladdercancer

Results from phase 2 CORE-008 CIS cohort with high-risk BCG-naïve NMIBC show an 83.7% complete response rate and favorable safety with cretostimogene. www.renalandurologynews.com/reports/cret... #SUO2025 #bladdercancer

What clinicians need to know about ASN’s guidance on potassium, phosphorus additives. Read our latest feature: www.renalandurologynews.com/features/asn... #kidneydisease

Belimumab showed efficacy in a subgroup of patients with lupus nephritis treated with MMF as standard of care background therapy. www.renalandurologynews.com/news/mycophe... #lupus

Patients with Crohn disease may have greater risk of radical prostatectomy complications than those with ulcerative colitis. www.renalandurologynews.com/news/prostat... #prostatecancer