Jane Yinghui Huang
@janehuang.bsky.social
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immunologist | phd in cell & molecular bio from e john wherry lab at upenn
Excited to share my graduate work from the
@ejohnwherry.bsky.social
lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in
@science.org
immunology. Main findings below!
www.science.org/doi/10.1126/...
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Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
TOX safeguards exhaustion biology in established Tex cells and restrains fate conversion to Teff cells.
https://www.science.org/doi/10.1126/sciimmunol.ado3032
8 months ago
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