We concluded #SMPS4 with a thought-provoking panel discussion on 'The Future of the Field.' A fitting end to an incredible conference, exploring the next frontiers in single-molecule protein sequencing!

Martin Charron from the University of Ottawa delivered a talk on 'Predicting Nanopore Electrical Signatures using Accurate Access Resistance Models for Optimized Protein Analysis.' #SMPS4

Justin Cronk from ETH Zürich presented on 'Adaptive Interfacial Nanopores with Glass Capillaries toward Protein Characterisation.' An innovative approach to advancing protein analysis! #SMPS4

Deanpen Japrung from the National Science and Technology Development Agency delivered a talk on 'Advanced Nanopore Sensing and AI-Driven Classification of Human Serum Albumin Variants: Implications for Kidney Function and Diabetes Diagnostics. #SMPS4

Next, Aleksandra Radenovic from EPFL presented on 'Advancing Frontiers in Nanopore Technologies and Scanning Ion Conductance Spectroscopy.' #SMPS4

We kick off the final day of #SMPS4 with Casey Platnich from the University of Cambridge, presenting on 'Nanopore sensing enables detection of topologically barcoded RNA and their associated proteins.' An exciting start to wrap up this incredible conference!

Xun Xu from MGI, one of our sponsors, wrapped up today’s sessions with a presentation on 'High-throughput Nanopore-based Peptide Sensing System.' We’re thankful for MGI's support! #SMPS4

Jagannath Swaminathan from Erisyon, one of our sponsors, presented on 'Robust and scalable single-molecule protein sequencing with fluorosequencing.' We are grateful for Erisyon's support! #SMPS4

Sanjin Marion from IMEC, one of our sponsors, presented on 'Solid state nanopores – fab to lab.' We appreciate IMEC's valuable support! #SMPS4

Andrew Heron, CEO of Portal Biotech and one of our sponsors, presented on 'Single-molecule identification and comprehensive PTM profiling of full-length proteins with nanopores.' We’re grateful for Portal Biotech's support! #SMPS4

Jayne Wallace, VP at Oxford Nanopore Technologies, one of our sponsors, delivered an inspiring talk. We appreciate their support! #SMPS4

Federico Thei, CEO and co-founder of Elements SRL, one of the proud sponsors of #SMPS4, shared his insights during a special session. We are grateful for Elements SRL’s support and Federico's engaging contribution to the conference!

Pranjal Sur from the Indian Institute of Science presented on 'Orientation Dependence of Current Blockade in Single Amino Acid Translocation through a Graphene Nanopore.' #SMPS4

Chen Kaikai from the University of Chinese Academy of Sciences delivered an enlightening talk on 'High-resolution glass nanopores for single-molecule detection.' #SMPS4

It was a privilege to hear Mauro Chinappi speak about 'Electroosmotic flow in nanopore protein sensing. #SMPS4

Ralph Scheicher from Uppsala University delivered an insightful talk on 'Insights from computational modelling: modified hydrophobic nanopores and impact of neighboring amino acids.' #SMPS4

Another brilliant session by Pablo Rivera-Fuentes from the University of Zurich on 'Single-Molecule Protein Identification using Blinking Patterns.' #SMPS4

Klara Hlouchova from Charles University gave an engaging presentation on 'Exploration of peptide sequence space: en route from prebiotic to biotic catalysis.' #SMPS4

Bauke Albada from Wageningen University & Research presented on 'An Orthogonal Click Approach to Convert Biological Proteins into Peptide-DNA Conjugates for Nanopore Reading. #SMPS4

Eric Anslyn from The University of Texas at Austin delivered an insightful presentation on 'Enabling the Chemistry of Fluorosequencing.' #SMPS4

Javier Kipen from KTH (Royal Institute of Technology) presented on 'Brownian motion data augmentation: a method to push neural network performance on nanopore sensors. #SMPS4

Amr Makhamreh from Northeastern University took the stage to present on 'Enzyme-Free Translocations of Denatured Proteins with Sequence Block Permutations through CytK Nanopores Yield Reproducible Signal Patterns. #SMPS4

Our next speaker, Joe Buonomo from the University of Texas at Arlington, presented on 'Scalable Native Peptide Sequencing Via Innovation in “Click” Chemistries and Large Language Models. #SMPS4

Our second speaker of the day, Sang Wook Lee from Ewha Womans University, delivered a captivating talk on 'Nano- and Micro-Electromechanical Mass Sensor with Sub-Zeptogram Resolution: Towards Single Molecule Protein Sequencing. #SMPS4

We started today with Aleksei Aksimentiev from the University of Illinois at Urbana-Champaign. He presented on 'Deciphering ionic current signatures of peptide transport through a biological nanopore #SMPS4

The final presentation of the day was by Wei-Lun Hsu from The University of Tokyo, who discussed 'Peptide Sensing by Monolayer Molybdenum Disulfide Nanopores. #SMPS4

Marija Drndic from the University of Pennsylvania followed with an intriguing talk on 'Investigation of folding dynamics of protein and peptide-oligonucleotide conjugates via solid-state nanopores. #SMPS4

Amit Meller from Technion – IIT took the stage next to present on 'Full-length proteins fingerprinting using solid-state nano-devices. #SMPS4

Big thanks to Kevin Freedman from the University of California Riverside for their engaging talk on 'Towards Deep-UV Raman Spectral Parsing of Amino Acid Side Chains inside a Plasmonic Nanopore. #SMPS4

Next, Javier Alfaro from the University of Gdansk took the stage to discuss 'Protein sequencing in complex mixtures by mass-spectrometry: How far have we come towards sequencing the proteome? #SMPS4

After lunch, we kicked off the afternoon session with Reuven Gordon from the University of Victoria. He delivered an enlightening presentation on 'Nanoaperture Optical Tweezers for Single Unmodified Protein Dynamics #SMPS4

🎉 #SMPS4 Group Photo! 🎉 A huge thank you to all the brilliant minds who joined us and made this event unforgettable. Your passion and insights are what drive this community forward. Here's to pushing the boundaries of science together! 🧬✨

We continued the day with an engaging session by @jeffnivala.bsky.social from the University of Washington presented on 'Unfoldase-driven, multi-pass nanopore reading of proteins in 2-amino-acid steps.' #SMPS4

Giovanni Maglia from the University of Groningen took the stage. He presented on 'Single-molecule characterization of native proteins with single amino acid resolution using nanopores' #SMPS4

After the coffee break, we were thrilled to welcome @ceesdekker.bsky.social from Delft University of Technology. He presented on 'Nanopore scanning of single proteins and their PTMs' Truly an inspiring session! #SMPS4

Our third presentation of the day was delivered by Hai-Chen Wu from the Institute of Chemistry, Chinese Academy of Sciences. He shared fascinating insights on 'Host-guest interaction-assisted nanopore protein sequencing.' #SMPS4

In our second session today Jia Geng shed light on Designed Protein Nanopore for Broad-Spectrum Molecular Recognition and Sensing #SMPS4

We kicked off the day with Shuo Huang from the University of Nanjing presenting on Nanopore proteomics performed by engineered Mycobacterium smegmatis porin A nanopores #SMPS4

We had the pleasure of hearing from Helena Miljkovic about: Controlled sensing of user defined aptamer-based targets using scanning ionic conductance spectroscopy #SMPS4

We learned so much from Camille Mitchell's session about:Towards in situ protein sequencing with Expansion Microscopy using in-gel Edman degradation and N-terminal amino acid binders #SMPS4

We just heard Sarah Sandler's presentation: DNA nanotechnology as a tool to advance understanding of neurodegeneration #SMPS4

Michael Mayer from University of Fribourg telling us about: Interrogating Single Proteins with Plasmonic Optical Tweezers: Opportunities and Challenges #SMPS4

Sonja Schmid from University of Basel talking about: Nanopore trapping for protein identification & beyond #SMPS4

Alex Kleiner : Solid-state sequencing based on carbon nanotube transistor with a pair of organic colour centres #SMPS4

Neilah Firzan talking about Fabrication of Mirror Image Nanopores at Molecular and Cellular Level #SMPS4

Jiandong Feng from Zhejiang University a fantastic talk about: Sensing amino acids with ultrathin nanopores #SMPS4

Follow by Chirlmin Joo: Decoding protein-peptide interactions with a sequencing platform #SMPS4

Our first talk after lunch, Yin Peng: Advancing proteomics with DNA probes #SMPS4

Verena Rukes telling us about: Charge-based fingerprinting of unlabeled full-length proteins using an aerolysin nanopore

Yujia Qing talking about Nanopore engineering: Playing a long game #SMPS4