Trustworthiness and Transparency Features Were Less Frequent in Randomized Trials Presenting Large Effects in Abstracts. Jonathan F. Henssler, Joana Reis-Pardal, Lina Koppel, John P.A. Ioannidis. medRxiv 2025.10.20.25338369; doi:

Effects of polygenic risk score communication on health outcomes: systematic review and meta-analysis. Luigi Russo, Nicolò Lentini, Sara Farina, Antonio Cristiano, Andrea Adduci, Alessio Perilli, Christian Cao, Roberta Pastorino, Stefania Boccia, JPA Ioannidis. medRxiv 2025

The architecture of exposome-phenome associations. Chirag J Patel, John PA Ioannidis, Arjun K Manrai. medRxiv 2025.06.05.25329055; doi:

Instability of Global Burden of Disease Estimates of Deaths and DALYs from Major Risk Factors. Emmanuel A. Zavalis, Angelo Maria Pezzullo, John P.A. Ioannidis. medRxiv 2025.11.14.25340145; doi:

Riedmann U, Sprenger M, Ioannidis JPA, Pilz S. Nationwide estimates of SARS-CoV-2 infection fatality rates and numbers needed to vaccinate for COVID-19 vaccines in 2024 in Austria. Eur J Clin Invest. 2025 Oct 25:e70135. doi.org/10.1111/eci....

Park JM, Sung BK, Myung JY, Lee SC, Yon DK, Shin JI, Kim YW, Ioannidis JPA. Adherence to Animal Research: Reporting of In Vivo Experiments Guidelines in Stem Cell Studies in Animal Models of Parkinson's Disease: A Systematic Review. Yonsei Med J. 2025 Nov;66(11):743-752 www.doi.org/10.3349/ymj....

METRICS is accepting applications for the 2026–27 postdoctoral fellowship in meta-research at Stanford. Deadline: Feb 15, 2026. Start date will be around Oct 1, 2026 (+/- 2 month flexibility). See: metrics.stanford.edu/postdoctoral... #MetaResearch #postdoc

Tomorrow 9am PT time: 𝐇𝐨𝐰 𝐑𝐞𝐩𝐫𝐨𝐝𝐮𝐜𝐢𝐛𝐥𝐞 𝐢𝐬 𝐇𝐞𝐚𝐥𝐭𝐡 𝐒𝐜𝐢𝐞𝐧𝐜𝐞 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡? by Niklas Bobrovitz and Stephana Moss, cover 38 metrics of reproducibility and 180 prevalence estimates. Registration at: stanford.zoom.us/meeting/regi...

Factors influencing the trustworthiness of non-randomized studies of interventions: a survey of international experts. Sally Yaacoub, John P. A. Ioannidis, Asbjørn Hróbjartsson, Raphaël Porcher, Philippe Ravaud, Isabelle Boutron. medRxiv 2025.09.24.25336459

Flanagin A, Godlee F, Goodman SN, Gunsalus CK, Ioannidis JPA, Knoll E. Remembering Drummond Rennie-Champion of Integrity in Science and Scientific Publication. JAMA. 2025 Sep 19. doi: 10.1001/jama.2025.18924.

Riedmann U, Rauch W, Schenk H, Oberacher H, Ioannidis JP, Pilz S. Number of Austrian SARS-CoV-2 infections in the 2024/2025 season: Analysis of national wastewater data. Public Health. 2025 Oct 2;248:105970. doi: 10.1016/j.puhe.2025.105970.

Haven TL, Ioannidis JPA. Reproducibility Failure in Biomedical Research: Problems and Solutions. Annu Rev Med. 2025 Oct 3. doi: 10.1146/annurev-med-050124-050859.