(@carlagal.bsky.social)

💡Our paper is out! Huge thanks for the support!♥️ We reveal how chaperones babysit unfolded proteins using ribosome profiling, single-molecule tools, and AlphaFold predictions. A simple rule drives complex folding across the proteome! www.nature.com/articles/s41...

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Proteome-wide determinants of co-translational chaperone binding in bacteria - Nature Communications This study integrates ribosome profiling, single molecule methods and computational predictions to reveal that molecular chaperones bind ‘unsatisfied’ residues exposed on partial nascent folds, ration... https://www.nature.com/articles/s41467-025-59067-9