Diego Forni
@diegoforni.bsky.social
📤 206
đź“Ą 205
đź“ť 12
a quiet boy that loves viral evolution
reposted by
Diego Forni
Microbiology Society
4 days ago
Fusobacterium abscessus sp. nov., associated with brain abscess in humans. Read more on this subject in IJSEM:
https://doi.org/10.1099/ijsem.0.007199
#IJSEM
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rdcu.be/ftHin
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Evolutionary history of LRRK2 and PRKN in leprosy and Parkinson’s disease
npj Genomic Medicine - Evolutionary history of LRRK2 and PRKN in leprosy and Parkinson’s disease
https://rdcu.be/ftHin
5 days ago
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Domain innovation and deeply conserved intrinsic disorders in eukaryotic argonaute
royalsocietypublishing.org/rsob/article...
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Domain innovation and deeply conserved intrinsic disorders in eukaryotic argonaute
Abstract. Argonaute (Ago) proteins are distributed across all domains of life and play central roles in the defence against mobile genetic elements. We per
https://royalsocietypublishing.org/rsob/article/16/7/260067/482456/Domain-innovation-and-deeply-conserved-intrinsic
11 days ago
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reposted by
Diego Forni
Society for Molecular Biology and Evolution
20 days ago
Trying to find a spot in the middle of the crowd at the Lumbya room for the "AI on molecular evolution" symposium
#SMBE2026
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The Story So Far: Intense Crowd Surfing
ALT: The Story So Far: Intense Crowd Surfing
https://static.klipy.com/ii/d7aec6f6f171607374b2065c836f92f4/8f/30/NUhF2yNG.gif?hh=280&ww=498&mp4=pXW40TTlEb0J&webm=pJGyyJcri70T
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Unstructured but dangerous—the emerging roles of intrinsically disordered protein regions in bacterial pathogenesis
doi.org/10.1002/1873...
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@manuelasironi.bsky.social
@febsletters.bsky.social
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FEBS Press
Intrinsically disordered regions (IDRs) are less common in bacteria than in eukaryotes but play key roles in virulence, adaptation, and host interactions. This review summarizes their properties, dis...
https://doi.org/10.1002/1873-3468.70368
about 2 months ago
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reposted by
Diego Forni
ManuelaSironi
4 months ago
link.springer.com/article/10.1...
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The evolutionary dynamics between viral mimics and host proteins - Molecular Systems Biology
Viral proteins interact with host proteins to hijack cellular pathways important for viral replication. Viral mimics are proteins whose structural similarity to host-mimicked proteins allows them to i...
https://link.springer.com/article/10.1038/s44320-026-00200-1
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Positive selection targeted primate genes that encode transposable element repressors
academic.oup.com/gbe/article/...
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Validate User
https://academic.oup.com/gbe/article/doi/10.1093/gbe/evag059/8507158
4 months ago
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rdcu.be/e4bnQ
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Urea transporter evolution: deep conservation, recent adaptation in mammals, and maintenance of the Jka/Jkb polymorphism in the past ~ 110,000 years
https://rdcu.be/e4bnQ
5 months ago
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Mycobacterium tuberculosis uses intrinsically disordered, fast evolving proteins to interact with conserved host factors
rdcu.be/eRsRf
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Mycobacterium tuberculosis uses intrinsically disordered, fast evolving proteins to interact with conserved host factors | Genome Biology
https://rdcu.be/eRsRf
8 months ago
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reposted by
Diego Forni
Molecular Biology and Evolution
9 months ago
What factors shape viral protein evolution? Fuchs et al. estimate evolutionary rates of numerous herpesvirus proteins and residues, revealing short- and long-term evolutionary constraints. đź”—
doi.org/10.1093/molbev/msaf256
#evobio
#molbio
#virus
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Functional and Structural Determinants of Long- and Short-Term Evolution of Herpesvirus Proteins
Abstract. Understanding the factors that shape viral protein evolution is a central question in evolutionary virology. However, these determinants are poor
https://doi.org/10.1093/molbev/msaf256
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I had a great time working with
@adnsvrtsn.bsky.social
on this one!
journals.asm.org/doi/10.1128/...
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Reassessing taxonomy and virulence in the Fusobacterium nucleatum group—rebuttal of Fusobacterium animalis clades “Fna C1” and “Fna C2,” genome announcement for Fusobacterium watanabei, and descriptio...
Considerable resources are being used to study associations between the human microbiota and malignancy. There is a particular interest in the connection between Fusobacterium animalis and colorectal ...
https://journals.asm.org/doi/10.1128/mbio.00941-25
12 months ago
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rdcu.be/eywjU
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The genus Akkermansia is populated by a multitude of biological species with a wide distribution in the animal kingdom | Biology Direct
https://rdcu.be/eywjU
12 months ago
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Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae | Microbiology Spectrum
journals.asm.org/doi/10.1128/...
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Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae | Microbiology Spectrum
We performed a proteome-wide investigation of intrinsically disordered regions (IDRs) in Mycoplasma pneumoniae (Mpn, class Mollicutes). A considerable fraction of the Mpn proteome (17%) is embedded in...
https://journals.asm.org/doi/10.1128/spectrum.00968-25
about 1 year ago
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academic.oup.com/ofid/advance...
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Population genetic structure and human adaptation of Kaposi Sarcoma-associated Herpesvirus
AbstractBackground. Kaposi Sarcoma-associated Herpesvirus (KSHV), the etiologic agent of Kaposi’s sarcoma, is human-specific and it is thought to have emer
https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofaf111/8038118
over 1 year ago
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www.researchsquare.com/article/rs-5...
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An ancient and still ongoing genetic conflict between transposable elements and their repressors
Background. Transposable element (TE) mobilization poses a significant fitness challenge to host genomes. Consequently, a variety of systems have emerged to silence TE activity. Just like TEs, such sy...
https://www.researchsquare.com/article/rs-5675976/latest
over 1 year ago
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reposted by
Diego Forni
Bosse lab at CSSB Hamburg
over 1 year ago
Our Herpesfolds paper is out in Nature Communications!
rdcu.be/d1uM7
Congrats to Timothy Soh, @sofiaaognibene , Saskia Sanders, Robin Schaeper and Benedikt Kaufer! Have a look at our database at
herpesfolds.org
by Malte Kansy
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Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium
www.nature.com/articles/s42...
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Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium - Communications Biology
Parsing the genetic diversity within the Fusobacterium genus provides ample evidence of species miss-classification and of undescribed species, and calls for a re-analysis of F. nucleatum features ass...
https://www.nature.com/articles/s42003-024-06825-y
almost 2 years ago
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