Diego Forni
@diegoforni.bsky.social
📤 196
📥 194
📝 9
a quiet boy that loves viral evolution
reposted by
Diego Forni
ManuelaSironi
6 days ago
link.springer.com/article/10.1...
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The evolutionary dynamics between viral mimics and host proteins - Molecular Systems Biology
Viral proteins interact with host proteins to hijack cellular pathways important for viral replication. Viral mimics are proteins whose structural similarity to host-mimicked proteins allows them to i...
https://link.springer.com/article/10.1038/s44320-026-00200-1
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Positive selection targeted primate genes that encode transposable element repressors
academic.oup.com/gbe/article/...
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Validate User
https://academic.oup.com/gbe/article/doi/10.1093/gbe/evag059/8507158
17 days ago
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rdcu.be/e4bnQ
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Urea transporter evolution: deep conservation, recent adaptation in mammals, and maintenance of the Jka/Jkb polymorphism in the past ~ 110,000 years
https://rdcu.be/e4bnQ
about 1 month ago
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Mycobacterium tuberculosis uses intrinsically disordered, fast evolving proteins to interact with conserved host factors
rdcu.be/eRsRf
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Mycobacterium tuberculosis uses intrinsically disordered, fast evolving proteins to interact with conserved host factors | Genome Biology
https://rdcu.be/eRsRf
4 months ago
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reposted by
Diego Forni
Molecular Biology and Evolution
5 months ago
What factors shape viral protein evolution? Fuchs et al. estimate evolutionary rates of numerous herpesvirus proteins and residues, revealing short- and long-term evolutionary constraints. đź”—
doi.org/10.1093/molbev/msaf256
#evobio
#molbio
#virus
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Functional and Structural Determinants of Long- and Short-Term Evolution of Herpesvirus Proteins
Abstract. Understanding the factors that shape viral protein evolution is a central question in evolutionary virology. However, these determinants are poor
https://doi.org/10.1093/molbev/msaf256
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I had a great time working with
@adnsvrtsn.bsky.social
on this one!
journals.asm.org/doi/10.1128/...
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Reassessing taxonomy and virulence in the Fusobacterium nucleatum group—rebuttal of Fusobacterium animalis clades “Fna C1” and “Fna C2,” genome announcement for Fusobacterium watanabei, and descriptio...
Considerable resources are being used to study associations between the human microbiota and malignancy. There is a particular interest in the connection between Fusobacterium animalis and colorectal ...
https://journals.asm.org/doi/10.1128/mbio.00941-25
8 months ago
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rdcu.be/eywjU
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The genus Akkermansia is populated by a multitude of biological species with a wide distribution in the animal kingdom | Biology Direct
https://rdcu.be/eywjU
8 months ago
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Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae | Microbiology Spectrum
journals.asm.org/doi/10.1128/...
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Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae | Microbiology Spectrum
We performed a proteome-wide investigation of intrinsically disordered regions (IDRs) in Mycoplasma pneumoniae (Mpn, class Mollicutes). A considerable fraction of the Mpn proteome (17%) is embedded in...
https://journals.asm.org/doi/10.1128/spectrum.00968-25
9 months ago
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academic.oup.com/ofid/advance...
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Population genetic structure and human adaptation of Kaposi Sarcoma-associated Herpesvirus
AbstractBackground. Kaposi Sarcoma-associated Herpesvirus (KSHV), the etiologic agent of Kaposi’s sarcoma, is human-specific and it is thought to have emer
https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofaf111/8038118
about 1 year ago
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www.researchsquare.com/article/rs-5...
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An ancient and still ongoing genetic conflict between transposable elements and their repressors
Background. Transposable element (TE) mobilization poses a significant fitness challenge to host genomes. Consequently, a variety of systems have emerged to silence TE activity. Just like TEs, such sy...
https://www.researchsquare.com/article/rs-5675976/latest
over 1 year ago
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reposted by
Diego Forni
Bosse lab at CSSB Hamburg
over 1 year ago
Our Herpesfolds paper is out in Nature Communications!
rdcu.be/d1uM7
Congrats to Timothy Soh, @sofiaaognibene , Saskia Sanders, Robin Schaeper and Benedikt Kaufer! Have a look at our database at
herpesfolds.org
by Malte Kansy
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Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium
www.nature.com/articles/s42...
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Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium - Communications Biology
Parsing the genetic diversity within the Fusobacterium genus provides ample evidence of species miss-classification and of undescribed species, and calls for a re-analysis of F. nucleatum features ass...
https://www.nature.com/articles/s42003-024-06825-y
over 1 year ago
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