Yang et al. review how gas therapy using molecules like nitric oxide, carbon monoxide, and hydrogen sulfide offers a promising new strategy to prevent and treat biofilm-associated infections by enhancing antibiotic efficacy and overcoming resistance. doi.org/10.4103/mgr.... #MedSky #neuroskyence

Missir & Cornwell show that #DaTSCAN and [18F]FDG PET are valuable for identifying underlying pathologies in corticobasal syndrome but remain insufficient for standalone diagnosis due to the condition's heterogeneity. doi.org/10.1016/j.ne... #Neuroimaging #Biomarkers #Neurology #MedSky #neuroskyence

Zhong et al. review cutting-edge technologies for spinal cord injury, showing that multimodal approaches combining #neurostimulation, cell therapies, and #tissueengineering are shifting SCI treatment from single interventions to integrated, personalized strategies. doi.org/10.4103/ATN.... #MedSky

Alshanberi & Ansari show that awareness of #Alzheimer's and #Parkinson's diseases is critically low among Saudi older adults, highlighting urgent needs for caregiver support, AI-driven early detection, and specialized #neurogeriatric care. journals.lww.com/aa/fulltext/... #MedSky #neuroskyence

Ferrara et al. review the growing evidence linking #vitaminD deficiency to #ADHD symptom severity and explore its potential as an adjunctive therapy through #neuroprotective and anti-inflammatory mechanisms. doi.org/10.4103/REGE... #MentalHealth #PublicHealth #MedSky #neuroskyence

Annaka shows that cognitive impairment is highly prevalent in chronic respiratory disease patients using long-term oxygen therapy and can critically impair their ability to operate life-sustaining equipment. doi.org/10.4103/mgr.... #ChronicRespiratoryDisease #RespiratoryCare #MedSky #neuroskyence

Neto & Pinho show that grip force variability analyzed with #deeplearning can serve as a novel #biomarker to accurately distinguish mid-stage #Parkinson's disease patients from healthy older adults. doi.org/10.1016/j.ne... #MachineLearning #NeuroMarkers #Neurology #MedSky #neuroskyence

Online now: Comparisons in microglial responses to ischemic–hypoxic #braininjury in neonatal and adult mice analyzed by transcriptome integration and deconvolution #technologies. doi.org/10.4103/ATN.... #Microglia #Neuroinflammation #Transcriptomics #SingleCell #StrokeResearch #MedSky #neuroskyence

Mahmoud et al. show that dual antiplatelet therapy (clopidogrel + aspirin) significantly reduces stroke recurrence and improves functional outcomes in older patients with mild-to-moderate ischemic stroke, but increases bleeding risk compared to aspirin alone. doi.org/10.4103/AGIN... #neuroskyence

Scolari & Granero show that #metalloantibiotics—transition metal complexes with antibiotics—offer a promising strategy to combat #osteomyelitis and enhance #bone regeneration by overcoming drug resistance and enabling local, sustained therapy. doi.org/10.4103/REGE... #Biomaterials #3DPrinting

Wu et al. review the dual role of nitric oxide in stroke—neuroprotective or neurotoxic depending on timing and dose—highlighting critical #therapeutic windows and the need for subtype-specific delivery strategies. doi.org/10.4103/mgr.... #StrokeResearch #NitricOxide #MedSky #neuroskyence

Online now:Dark white matter is a subcortical MRI marker in seizures and systemic disorders: A narrative review. doi.org/10.1016/j.ne... #DarkWhiteMatter #Neuroimaging #Epilepsy #MRI #Seizures #MOGAD #Neurology #Biomarker #MedicalResearch #BrainMRI #StatusEpilepticus #MedSky #neuroskyence

Chen et al. show that a time-squared augmented Lyapunov functional improves sampled-data #synchronization for chaotic neural networks, reducing conservatism and enhancing control precision. doi.org/10.4103/ATN.... #NeuralNetworks #NeuromorphicComputing #NonlinearDynamics #MedSky #neuroskyence

Correa et al. show that tropicamide, an M4 muscarinic receptor antagonist, reverses catalepsy and motor impairments in a haloperidol-induced mouse model of #Parkinson’s disease. doi.org/10.4103/AGIN... #Neuroscience #Tropicamide #MuscarinicReceptors #AgingResearch #MedSky #neuroskyence

Bokor & Fodor show that autologous retinal transplantation achieves high closure rates in refractory full-thickness macular holes, offering a promising solution for cases where standard surgery fails. doi.org/10.4103/REGE... #Ophthalmology #MacularHole #Vitrectomy #MedSky #neuroskyence

Chen et al. review how the #gasotransmitter hydrogen sulfide (H₂S) acts as a multitarget regulator to protect the brain, heart, kidney, liver, and lung from #ischemia-reperfusion injury by modulating inflammation, oxidative stress, and cell death pathways. doi.org/10.4103/mgr.... #H2S #MedSky

Kumar et al. review how #neurobiomarkers like glutathione, amyloid-β, and PD-L1 are driving new diagnostic and therapeutic strategies for #Alzheimer's, #Parkinson's, and glioblastoma. doi.org/10.1016/j.ne... #Neurology #GeneTherapy #Nanomedicine #BrainResearch #NeuroMarkers #MedSky #neuroskyence

Zhao et al. show that combining machine learning with #miRNA #biomarkers can diagnose epilepsy with up to 95.45% accuracy, offering a promising non-invasive alternative to traditional EEG methods. doi.org/10.4103/ATN.... #EpilepsyResearch #MachineLearning #Neurology #MedTech #MedSky #neuroskyence

Liu et al. review how animal-derived #peptides — from scorpion venom to deer antler velvet—show promise in combating aging-related diseases like tumors, thrombosis, diabetes, and #neuroaging. doi.org/10.4103/AGIN... #AgingResearch #TraditionalChineseMedicine #MedSky #neuroskyence #DrugDiscovery

Zhang et al. show that Sanghuang, a traditional medicinal fungus, may ameliorate #liverinjury and promote #regeneration by targeting multiple pathways including HIF-1α and MAPK signaling. doi.org/10.4103/REGE... #TraditionalChineseMedicine #NetworkPharmacology #MolecularDocking #MedSky #neuroskyence

Hu et al. show that sevoflurane postconditioning alleviates cognitive impairment after hemorrhagic shock and resuscitation by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #AnestheticGas #Sevoflurane #CognitiveImpairment #Neuroprotection #MedicalResearch #MedSky #neuroskyence

Silva et al. review how #aging impairs hippocampal #neurogenesis through serotonergic system dysfunction, and demonstrate that #aerobicexercise effectively counteracts these effects by modulating 5-HT activity and promoting #brain plasticity. doi.org/10.1016/j.ne... #Neuroscience #neuroskyence

Zhou et al. review how #brainorganoids— including vascularized, tumor, and #neurodegenerative models—are revolutionizing the study of #cerebrovascular diseases, brain tumors, and disorders like #Alzheimer's and #Parkinson's. doi.org/10.4103/ATN.... #Neuroscience #Glioblastoma #StemCells #Biomedical

Chen reviews how gamma oscillations shift with #aging and shows that gamma entrainment— tailored to an individual’s natural frequency—could serve as both an early #biomarker and a non-invasive therapy to preserve cognitive function and delay #neurodegeneration. doi.org/10.4103/AGIN... #Neurology

Shah et al. show that shorter #cardiopulmonary bypass and cross-clamp times—and the need for balloon atrioseptostomy—are associated with developmental delay in neonates after #arterialswitch operation for transposition of the great arteries. doi.org/10.4103/REGE... #Neurodevelopment #MedSky

Sevoflurane #postconditioning alleviates cognitive impairment after hemorrhagic shock by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #Sevoflurane #CognitiveImpairment #HemorrhagicShock #Neuroprotection #SIRT1 #HIF1α #NLRP3 #MedicalResearch #Anesthesia #MedSky #neuroskyence

New study by Zhang et al. identifies four long non-coding RNAs in blood as promising biomarkers for diagnosing major depression and predicting treatment response. doi.org/10.1016/j.ne... #Depression #Biomarkers #lncRNA #MentalHealth #Neuroscience #Research #Psychiatry #RNA #MDD #MedSky #neuroskyence

Machine learning combined with resting-state EEG enhances diagnostic accuracy for psychiatric disorders, offering a path toward objective biomarkers. doi.org/10.4103/ATN.... #MachineLearning #EEG #Psychiatry #Biomarkers #MentalHealth #AI #Neuroscience #MedSky #neuroskyence

#AI-powered detection of cellular #Senescence is revolutionizing #Aging research! AUTHORS show that artificial intelligence enables accurate identification and quantification of senescent cells through advanced imaging and #DeepLearning models. doi.org/10.4103/AGIN... #Biomarkers #Longevity #MedSky

New study finds K-wire fixation yields better functional outcomes for olecranon fractures compared to screw-based #TensionBandWiring. doi.org/10.4103/REGE... #OlecranonFracture #KirschnerWire #CancellousScrew #OrthopedicSurgery #TraumaCare #FunctionalRecovery #FractureFixation #SurgicalOutcomes

CT-guided oxygen-ozone injection offers superior long-term pain relief and functional recovery for lumbar disc herniation with spinal stenosis compared to epidural steroids. doi.org/10.4103/mgr.... #OzoneTherapy #MinimallyInvasive #SpinalHealth #PainRelief #MedicalResearch #MedSky #neuroskyence

Study finds cataracts are associated with an increased risk of Parkinson’s disease, suggesting they may serve as a potential non-motor marker. doi.org/10.1016/j.ne... #ParkinsonsDisease #Cataract #Neurodegeneration #Biomarker #UKBiobank #ObservationalStudy

Shu et al. found that downregulation of #microtubule proteins TUBB2A, TUBB3, and TUBB4B contributes to #neuronaldysfunction in #Alzheimer’s disease by impairing microtubule stability and promoting tau pathology. doi.org/10.4103/AGIN... #Tubulin #Neuroscience #Bioinformatics #ADresearch #Aging

New technologies for improving the accuracy of #Neuroimaging: A stochastic Gaussian-masked #denoiser significantly enhances the visualization of subcellular structures and neural dynamics without requiring training data. doi.org/10.4103/ATN.... #Neuroscience #Microscopy #CalciumImaging #Bioimaging

New research using NHANES data finds that higher relative fat mass (RFM) is negatively associated with lumbar bone mineral density in U.S. adults aged 20–59. doi.org/10.4103/REGE... #Osteoporosis #BoneHealth #RFM #NHANES #Obesity #PublicHealth #RegenerativeMedicine

Liu et al. present a bibliometric and scientific mapping analysis of AI-driven nitric oxide clinical applications, highlighting knowledge gaps and translational challenges. doi.org/10.4103/mgr.... #ArtificialIntelligence #NitricOxide #MedicalAI #Bibliometrics #ClinicalResearch

Li et al. reviewed the roles of circular RNAs at synapses and their potential as biomarkers for neurological disorders. doi.org/10.1016/j.ne... #circRNA #Synapse #Biomarkers #Neurodegeneration #Alzheimers #Neuroscience #BrainResearch

New #Neuroscience tech enhances #Synchronization in chaotic neural networks using time-squared #Lyapunov functionals—improving control with sampled data and actuator saturation. doi.org/10.4103/ATN.... #ChaoticNeuralNetworks #SampledDataControl #BrainInspiredComputing #Neuromorphic #NonlinearSystems

New study finds valvular heart disease, hypertensive heart disease, and endocarditis increase risk of systemic lupus erythematosus, reveals shared genetic links. doi.org/10.4103/AGIN... #Lupus #HeartDisease #MendelianRandomization #Genetics #Cardiology #Autoimmune #SLE #GWAS #MedicalResearch

New study finds 100% inspired oxygen does not increase delayed neurocognitive recovery risk in patients undergoing one-lung ventilation compared to 70% oxygen. doi.org/10.4103/mg.M... #Anesthesia #CognitiveRecovery #Surgery #MedicalResearch #ThoracicSurgery #ClinicalTrial

Sun et al. comprehensively review the potential of in vivo #RenalRegeneration to overcome limitations of transplantation and dialysis by activating endogenous repair mechanisms, using #StemCells, biomaterials, and vesicles. doi.org/10.4103/REGE... #KidneyDisease #RegenerativeMedicine #Nephrology

New comparative study reveals significant bias across Quanterix Simoa assay formats for neurological biomarkers NfL and GFAP, highlighting the need for data harmonization. doi.org/10.1016/j.ne... #Biomarkers #Neurofilament #GFAP #Simoa #Neurology #AssayValidation

Exciting research: Zhao et al. developed a machine learning model using miRNA biomarkers that achieved 95.45% accuracy in diagnosing epilepsy, offering a novel, non-invasive diagnostic approach. doi.org/10.4103/ATN.... #Epilepsy #MachineLearning #miRNA #Neurology #AI #Biomarkers #Neurotech

Chu et al. shows that osteoarthritis prevalence and DALYs are rising globally, driven by aging, high BMI, metabolic factors, and significant sex disparities. doi.org/10.4103/AGIN... #Osteoarthritis #GlobalHealth #Aging #DALYs #GBD #PublicHealth #Epidemiology

Gamma entrainment as a therapeutic modality for the aging brain: a narrative review Chen reviews how #GammaEntrainment can serve as a biomarker and therapeutic intervention to restore neural dynamics in the #AgingBrain. doi.org/10.4103/AGIN... #AgingAdvances #Neurodegeneration #CognitiveDecline

Gao et al. demonstrate a novel #neuroscience technique using time-squared augmented Lyapunov functionals to improve #synchronization in #ChaoticNeuralNetworks under sampled-data control and actuator saturation. doi.org/10.4103/ATN.... #SampledDataControl #Lyapunov #ControlTheory

Peng et al. show #hyperbaricoxygentherapy exerts neuroprotective effects in #SpinalCordInjury via anti-inflammatory, antiapoptotic & antioxidant mechanisms, but optimal protocols & long-term efficacy need validation. doi.org/10.4103/mgr.... #HBOT #Neuroprotection #MedicalGasResearch

#Ferroptosis in osteogenic differentiation: a narrative review of bone regeneration metabolism Huang et al. review how ferroptosis—an iron-dependent form of cell death—affects bone healing by disrupting iron metabolism and increasing oxidative stress in bone-related cells. doi.org/10.4103/REGE...

Roles of circular RNAs targeted to #synapses: Narrative review of potential mechanisms and biomarkers Li et al. review the roles of #CircularRNAs in synaptic function and their potential as #biomarkers for #neurodegenerativediseases. www.sciencedirect.com/science/arti...

Yao et al. demonstrate that engineered #exosomes hold significant therapeutic potential for promoting peripheral #nerveregeneration through enhanced targeting and bioactive delivery. doi.org/10.4103/ATN.... #RegenerativeMedicine #TissueEngineering #BiomedicalResearch #Bioengineering