🧬 Ever wonder how fast your DNA changes from one generation to the next? @hdashnow.bsky.social and her team explored how quickly the human genome mutates by analyzing DNA from four generations of a single family. Dive into this video from @nature.com ⤵️

A collaboration between CU Anschutz, iNFixion, Mass General, and Harvard reveals how losing one gene reshapes cells in NF1. Using Cell Painting and machine learning, researchers built a model to detect subtle changes in Schwann cells, paving the way for targeted treatments.

A chatbot that looks and sounds like your doctor? Matthew DeCamp, MD, says we need to ask: ✅ Do patients know it’s AI? ✅Do they understand its limits? ✅Do they have a choice? Ethics must guide AI in healthcare ➡️ https://bit.ly/4pBvOeK

Andrea Sikora, PharmD, joins @drugtopics.bsky.social to discuss new ICU guidelines that formally recognize pharmacists as essential care team members. In this podcast, she shares how the guidelines could reshape pharmacy practice across health care. 🎧 Listen here: https://bit.ly/41ORE4e

On #WorldSepsisDay, we’re spotlighting Tell Bennett, MD, MS, who led the first update to pediatric sepsis criteria in nearly 20 years. His team is already working on tools to bring these criteria into hospitals, including EHR-integrated decision support systems ➡️ https://bit.ly/4pmuZ9f

New review alert: Genetic Studies Through the Lens of Gene Networks Traditional GWAS and TWAS miss gene–gene interactions. This piece reviews leveraging machine learning methods to identify gene modules based on coexpression and functional relationships.

Our very own, @bstranger.bsky.social, lit up the stage at the Headstrong Comedy Show, where science met satire to tackle misconceptions in women’s health. Hosted by Brainfest at the Bug Theater, the night was a bold blend of laughs and learning.

Should you pay extra for AI to read your mammogram? CU Anschutz’s Carie Behounek sat down with David Kao, MD, DBMI secondary faculty member, to unpack the promise, pitfalls, and price of AI in breast cancer screening. Read the Q&A ➡️ https://bit.ly/4nfsPGU

New national guidelines, led by ‪@cuanschutz.bsky.social‬ experts in DBMI and ‪@cupharmacy.bsky.social‬, recognize the vital role pharmacists play in improving outcomes through comprehensive medication management. This shift sets new standards for safer, more personalized care.

A new study from researchers at ‪@colorado.edu‬ and @cuanschutz.bsky.social‬ reveals how genetics shape body size, fat distribution, and health risks. This research helps us understand obesity beyond diet and lifestyle, showing how biology plays a powerful role.

From speed collaborating to visionary pitches, our annual DBMI retreat sparked fresh ideas and new connections. Faculty, staff, and students came together to reimagine the future of biomedical informatics.

CU Anschutz 🤝UCLA We were thrilled to host @alice.soragnilab.com from UCLA at @cuanschutz.bsky.social. She’s teaming up with @casey.greenelab.com to drive innovation and improve patient outcomes. This collaboration is a powerful example of how partnerships accelerate scientific discovery.

Big leap in genomics! The Norman Lab at the @cumedicalschool.bsky.social helped build one of the most complete maps of the human genome ever.

🎉 Congrats @audreyhendricks.com on receiving the 2025 ASHG Education Award! Hendricks is recognized for her contributions to human genetics and genomics education. From founding training programs to mentoring the next generation of scientists, she continues to make a lasting impact on the field.

With software engineers from @cubiomedinfo.bsky.social, we developed Manugen-AI, an agentic AI system to automate the mechanical tasks of writing a scientific article #adkhackathon Check it out! Devpost: devpost.com/software/aca... Code: github.com/pivlab/manug... Medium: medium.com/@miltondp/ma...

Explore research from Yanjun Gao, PhD, on LLMs’ capabilities in understanding and representing structured electronic health record data for clinical prediction, which was accepted at the annual EMNLP meeting ▶️https://buff.ly/4a0tAOJ

Wishing you all a joyful and festive holiday season 🌟

We had a blast with Dr. Emily Gibson, DO, as she shared some awesome tips on posture and how to sit right and work right! We even got moving with a fun group exercise that got us all off our feet!

In cancer transcriptomics, it's believed that smaller, simpler models generalize better. But does this hold true for gene expression-based predictive models across datasets and cancer types? Learn more ▶️ https://buff.ly/3P2OFOx

What a view 🤩

I am excited to present STRchive.org v2! A resource for tandem repeats associated with Mendelian disease. We have resigned the website, added new loci, streamlined our data for easier reuse, added more detailed citations, presented population frequency data and more!

Big congratulations to Hayley Wolff! After 4 years of hard work, late nights and groundbreaking research, she’s set to graduate with her PhD! This milestone is a testament to her dedication, innovation and passion for advancing science ▶️ https://buff.ly/3ZLKVqV

Decision-making is a crucial part of our daily lives. During November's Bytes to Bedside, we delved into the fascinating intersection of #AI and cardiology and explored the complexities of decision-making and the impact of bias ▶️ https://buff.ly/3ZC05ho

We couldn’t agree more 🏔️🤩

Critical care pharmacists are vital in ICUs, providing comprehensive medication management for critically ill patients. But are there standardized, meaningful productivity metrics for them? Learn more from Andrea Sikora, PharmD, and colleagues ▶️ https://buff.ly/41owsCo

It’s amazing to see our students shine! At the recent Tattered Cover health series, Brook Santangelo from the Computational Bioscience Graduate Program presented her research alongside Cathy Lozupone, PhD. Explore their work ▶️ https://buff.ly/4fZ4JfU

Explore how Antonio Porras, PhD, uses #AI to help surgeons personalize their plans for delicate corrective procedures while also deepening the understanding of conditions like craniosynostosis—a disorder where a baby’s skull bones fuse too early ▶️ https://buff.ly/4f40QFn

Betzaida Maldonado, a @cuanschutz.bsky.social trainee, will use funding from the NIJ to tackle the challenges of traditional forensic testing regarding samples that are mixtures from multiple individuals—an issue commonly encountered at crime scenes. Explore her research ▶️ https://buff.ly/41dJmDm

The postdocs (me and @evanbrenner.bsky.social ) enjoying the Holiday Selfie Station on day 1 of Byte Into Sweets, Holiday Edition at @cubiomedinfo.bsky.social | @cuanschutz.bsky.social

I had so much fun visiting the BU Biostats Dept a couple weeks ago! What an amazing place! www.bu.edu/sph/news/art...

A study from the Norman Lab at DBMI, published in @cellpressnews.bsky.social, shows that the KIR3DLI*114 allele, found in First Nations inhabitants of Oceania, could impact immunity. 🧬The team aims to use their research to address today's health disparities ▶️ buff.ly/3Zhbx2K

This week's Tattered Cover session with Cathy Lozupone, PhD, and trainee Brook Santangelo was a hit! Their insightful talk on "The Role of the Intestinal Microbiome in Health" explored how our gut shapes our health. Learn more ▶️ https://buff.ly/4fZ4JfU

We had an amazing time exploring AI in cardiology with Mike Rosenberg, MD, during this week's Bytes to Bedside! From the latest #tech in clinical settings to the powerful potential use of #AI for method improvement, it's exciting to see how we're revolutionizing healthcare.

Explore how DBMI is revolutionizing care where it matters most: at the bedside ▶️ bit.ly/4hZwkzm