Rocket Pharma has withdrawn a filing in the US for its experimental gene therapy for Fanconi anaemia, but may consider partnering the programme. pharmaphorum.com/news/rocket-...

Cidara is celebrating a major injection of funding from the US government for its experimental one-shot, universal flu prophylactic CD388. pharmaphorum.com/news/cidara-...

European doctors have said GLP-1 drugs are so effective in obesity that they should be the first choice drug treatment in almost all cases. pharmaphorum.com/news/glp-1s-...

Can FDA approval of Jazz Pharma's Zepzelca in a combination regimen for extensive-stage small cell lung cancer return sales of the drug to growth? pharmaphorum.com/news/jazz-ro...

The FDA has cleared another generic of the abortion pill mifepristone, as it carries out a review of the drug that has been criticised as spurious. pharmaphorum.com/news/fda-ang...

Speculation is building that President Donald #Trump may delay the introduction of his 100% #tariff rate on #pharmaceuticalimports in order to negotiate more deals with drugmakers on #drugpricing.

#BristolMyersSquibb, #Takeda, and #AstexPharma have joined a recently formed #consortium that is working on refining the #OpenFold structure prediction platform with pharma industry #data.

#CrystalysTherapeutics has emerged from its cocoon with $205 million first-round #financing and a potential treatment for #gout that is already in phase 3 testing. pharmaphorum.com/news/crystal...

#Indivior has agreed to halt all marketing of its #opioidoverdosedrug Opvee in New York after being rapped by the state attorney general for #mispromoting it to health officials. pharmaphorum.com/news/indivio...

One of the pioneers of in vivo #celltherapy, #UmojaBiopharma, has cleared another regulatory milestone after getting a #fasttrackdesignation from the FDA for its lead candidate for #bloodcancers, partnered with #AbbVie.

#Novartis has claimed a first-in-class #regulatoryapproval in the US for oral #BTKinhibitor remibrutinib as a second-line treatment for #chronicspontaneousurticaria (CSU), also known as chronic #hives.

The #USgovernment has shut down after Republicans and Democrats failed to resolve a #standoff on the #budget and the federal government ran out of money. pharmaphorum.com/news/hhs-sta...

President Trump and Pfizer CEO Albert Bourla announced a historic deal aiming to bring drug prices in line with other countries -- and Pfizer is just the first company to sign, Trump promised.

The results of a phase 3 trial of #Vertanical's #cannabis-derived therapy VER-01 for chronic lower #backpain have been published, and bode well for the ongoing reviews of marketing applications for the drug. pharmaphorum.com/news/data-ba...

A new £1.2 billion #scienceandtechnologypark was formally opened today in #Oxford, in a welcome boost to the #UK's #lifesciences sector.

An #online #NHS #hospital will launch in #England within two years to help cut #waitingtimes, according to the #UKgovernment. pharmaphorum.com/news/uk-says...

For the second time in the space of a week, a big #pharma group has served notice that it plans to charge the same #price for one of its new #medicines in the #UK as it does in the #US. pharmaphorum.com/news/abbvie-...

The pharma industry is embracing #DirectToConsumer selling of medicines in the US, and industry organisation #PhRMA has stepped in to help cut out the middlemen in the #supplychain. pharmaphorum.com/news/phrma-u...

#Shares in #EnantaPharma were sliding this morning after the US company reported #results of a phase 2b trial of its respiratory syncytial virus (#RSV) treatment zelicapavir that missed the primary endpoint. pharmaphorum.com/news/enanta-...

#AstraZeneca is the latest big pharma group to open up a #DirectToConsumer sales channel in the #US, offering three of its drugs at a big #discount to #cashbuyers. pharmaphorum.com/news/astraze...

Antibody specialist #Genmab has continued its shift from out-licensing drugs to developing its own medicines with a deal to buy #Merus and its lead drug candidate for #headandneckcancer for around $8 billion. pharmaphorum.com/news/genmab-...

This week has kicked off with the unexpected news that #EmmaWalmsley is standing down as chief executive of #GSK after eight years, to be replaced by current chief commercial officer #LukeMiels. pharmaphorum.com/news/walmsle...

#BristolMyersSquibb has expanded its direct-to-consumer (#DTC) sales of #medicines in the US with the addition of its #psoriasis therapy Sotyktu.

The #FDA has approved #EliLilly's oral selective oestrogen receptor degrader (#SERD) imlunestrant as a treatment for relapsed or refractory advanced #breastcancer with a specific mutation in the #oestrogenreceptor.

After all the threats, it seems President #Trump's #tariffs on #pharmaceuticals are coming to fruition, and a lot sooner than expected.

Wearable technology developer #Biolinq has won FDA authorisation for a #biosensor that can measure #glucose levels continuously just beneath the skin's surface, without the need for a needle. pharmaphorum.com/news/biolinq...

Merck KGaA's CEO Belén Garijo will step down next year and will be replaced by the group's electronics boss Kai Beckmann.

MSD has moved a step closer to completing its acquisition of Verona Pharma, after a vote in favour of the transaction by the UK firm's shareholders. pharmaphorum.com/news/verona-...

AstraZeneca has elevated its challenge to Medicare drug price negotiation powers to the Supreme Court of the US. pharmaphorum.com/news/az-take...

US biotechs Acadia Pharma and Harmony Biosciences have both suffered setbacks in phase 3 trials of drugs for rare diseases, in one case ending the programme. pharmaphorum.com/news/acadia-...

The UK government has celebrated the opening of #Moderna 's £150m vaccines facility, but storm clouds continue to gather on the issue of drug pricing. pharmaphorum.com/news/moderna...

#uniQure's #genetherapy for #Huntington's has hit the mark in a clinical trial, raising hopes of the first treatment for the devastating #neurodegenerativedisease. pharmaphorum.com/news/joy-uni...

#MSD has signed an agreement with #VariationalAI to use its generative AI (#genAI) platform Enki in the discovery of new small-molecule medicines.

#BristolMyersSquibb has said it hopes to be ready soon to file for approval of its #multiplemyeloma drug iberdomide after reporting positive results in a phase 3 trial.

A big part of #Biogen's efforts to defend its #spinalmuscularatrophy (SMA) business has been dealt a setback by the FDA, which declined to approve a high-dose version of its flagship #Spinraza product. pharmaphorum.com/news/fda-kno...

#EliLilly has selected Houston, Texas, as the location for a major new facility for active pharmaceutical ingredients (#APIs) in the US that will support its fast-growing weight-loss business. pharmaphorum.com/news/lilly-n...

Unresolved #compliance issues at a #manufacturing plant operated by #NovoNordisk have led to a #completeresponseletter for #ScholarRock's lead drug for #spinalmuscularatrophy (SMA).

#Roche has staked a claim to use its oral selective oestrogen receptor degrader (#SERD) giredestrant as a second-line therapy for #breastcancer, regardless of a patient's ESR1 mutation status.

#AngeliniPharma has licensed a preclinical-stage #mTORinhibitor from South Korean biotech #Sovargen with potential for genetic forms of #epilepsy and other brain disorders.

The consequences of President #Trump's actions on #drugpricing continue to play out, with #BristolMyersSquibb insisting it will charge the same in the UK for new #schizophrenia drug Cobenfy as in the US.

Medical groups have reacted with dismay as President #Trump has linked #childhoodvaccinations and use of the painkiller #acetaminophen in pregnancy to #autism. pharmaphorum.com/news/alarm-t...

#Bayer's much-anticipated #stemcelltherapy for #Parkinsonsdisease is gathering momentum, with dosing in phase 3 trials now underway.

#StealthBioTherapeutics has claimed FDA approval for #Forzinity, the first treatment for ultra-rare disease #Barthsyndrome, just a few months after it was turned down by the regulator. buff.ly/81DU9RM

#MSD's cancer #immunotherapy #Keytruda will soon be available as a #subcutaneousinjection that does away with the need to visit an infusion clinic. pharmaphorum.com/news/fda-cle...

On the second day of its latest meeting, the #CDC's #vaccinecommittee reduced some support for #COVID19 vaccines, but did not go as far as some might have feared in limiting access. pharmaphorum.com/news/covid-1...

The Advisory Committee on Immunization Practices (#ACIP) has agreed to push back a vote on changing the #CDC recommendation for a #birth dose of the #hepatitisB virus (HBV) #vaccine, as panellists were unhappy with the wording of the resolution. pharmaphorum.com/news/breakin...

#Biogen has reached a deal to buy #AlcyoneTherapeutics, a privately held company that has developed a system for delivering antisense oligonucleotides (#ASOs) directly into the #centralnervoussystem.

UK #medtech firm #ClosedLoopMedicine has launched its first product in the US, a #digitaltool for personalising the #dose of #GLP1 agonist-based #weightloss therapies. pharmaphorum.com/news/closed-...

Just a few months after emerging from the Flagship Pioneering incubator with $200 million in seed #financing, #LilaSciences has raised another $235 million in a first round that will further the development of its #AI-powered, fully #autonomous #labtechnology. pharmaphorum.com/news/lila-sc...

The #UK's Royal College of #Psychiatrists (RCPsych) has published a report that calls for more clinical testing of #psychedelicmedicines, as there is currently a lack of "high-quality evidence" to support their use. pharmaphorum.com/news/uk-spec...