Prof Albé van der Merwe
@albevdmerwe.bsky.social
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Evolutionary biologist, geneticist, tech enthusiast, musician. Student of all sciences.
Schizophyllum commune in my garden, on an old tree stump.
7 months ago
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Genome annotation is one of the things that we really need AI / machine learning to crack. New software makes it a little easier, but this one is a really interesting take on the problem.
www.nature.com/articles/s41...
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EvoWeaver: large-scale prediction of gene functional associations from coevolutionary signals - Nature Communications
Despite having structures for most proteins, we still do not know their function. Here, authors introduce EvoWeaver, a de novo method to identify genes working together using evolutionary information....
https://www.nature.com/articles/s41467-025-59175-6
8 months ago
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reposted by
Prof Albé van der Merwe
Fyodor Urnov
8 months ago
It will take a while for upper-div Genetics textbooks to adapt, but adapt they must: the underlying basis for every single one of the trait differences Mendel studied is now known. Cue Janáček's Moravian dances in celebration! (see post below)
www.nature.com/articles/s41...
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Genomic and genetic insights into Mendel’s pea genes - Nature
Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their m...
https://www.nature.com/articles/s41586-025-08891-6
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We were in Kruger National Park and this hyena just casually strolled past the car.
8 months ago
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