A tour de force study from Taipale&Yin labs. It expands the vocabulary of the Regulatory Code by adding 1131 TF:TF composite motifs that are different from the individual TF motifs. The new composite motifs are enriched in cell-type specific elements and active in vivo www.nature.com/articles/s41...

Happy to present the first preprint from my lab after relocating @CHOP_Research @ChildrensPhila Here we describe gene expression at the single cell level across major milestones of human and mouse development. preprint here: https://buff.ly/3PFWNoG

Impressive study from Alex Stark lab identifying 3 new types of silencer elements in Drosophila New TF binds a particular isolated motif in non-accessible sites to recruit G9a. Deletion of these elements can lead to upregulation of nearby gene www.sciencedirect.com/science/arti...