Piel Lab (@piellab.bsky.social)

Happy to share work by Maria and awesome collaborators published in Nature Chem Bio! Using metagenomic, single-bacterial, and biochemical methods we provide insights into uncultivated bacterial symbionts as rich sources of bioactive natural products in marine sponges. #DrugDiscovery #NaturalProducts

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Chemical richness and diversity of uncultivated ‘Entotheonella’ symbionts in marine sponges - Nature Chemical Biology Marine sponges host bacteria that produce diverse bioactive compounds. Here, the authors conduct a large-scale metagenomic, single-bacterial and biochemical study to reveal the untapped biosynthetic p... https://www.nature.com/articles/s41589-025-02066-0#Abs1