Danfeng Chen
@danfengc.bsky.social
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PhD candidate in Storey Lab @Princeton University | Statistical genetics
reposted by
Danfeng Chen
Yushi Tang
about 1 year ago
Delighted to introduce our work on causal inference for genotype-phenotype analyses, with some thoughts about randomization in genetics
www.biorxiv.org/content/10.1...
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Identifying causal genotype-phenotype relationships for population-sampled parent-child trios
The process by which genes are transmitted from parent to child provides a source of randomization preceding all other factors that may causally influence any particular child phenotype. Because of th...
https://www.biorxiv.org/content/10.1101/2024.12.10.627752v1
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Happy to share "super admixture", a new framework for modeling the human population structure!
www.biorxiv.org/content/10.1...
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Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution
The admixture model is widely applied to estimate and interpret population structure among individuals. Here we consider a "standard admixture" model that assumes the admixed populations are unrelated...
https://www.biorxiv.org/content/10.1101/2024.12.29.630632v1
about 1 year ago
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