Andreas Fellas (@andreasfellas.bsky.social)

Robin Allshire 🇮🇪 🇪🇺✊🏿 ⬆️ Zak’s favourite nucleosome: K9me about 1 year ago

Our latest Preprint is now on BioRXiv: www.biorxiv.org/content/10.1... It explains how heterochromatin-dependent epimutations mediate resistance to caffeine & antifungals by imposing mitochondrial dysfunction. Thanks to all authors for their efforts especially Andreas Fellas & Alison Pidoux. Enjoy!

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Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance Global health and food supply are endangered by an increasing frequency of antifungal resistance in pathogenic fungi. Wild-type fission yeast, Schizosaccharomyces pombe, can gain resistance to insults... https://www.biorxiv.org/content/10.1101/2024.11.13.623381v1