New review article in The Lancet Microbe Safety and efficacy of #phage application in bacterial decolonisation: a systematic review www.thelancet.com/journals/lan... #bacteriophage #OpenAccess #OA

Super interesting study on the use of phage in the environmental surveillance of Salmonella Typhi journals.plos.org/plosntds/art...

Smart stuff, we have been looking at scavenging systems and signalling in E. coli with respect to phage sensitivity but this is nice & specific… doi.org/10.1038/s414...

The links between Epstein-Barr virus infection and later multiple sclerosis are getting stronger: www.science.org/content/blog...

Question on plagiarism software. We use Turnitin at our university but Food Standards Scotland are interested in using something like this but Turnitin very expensive. Does anyone have experience with other software? What do the journals use?

Re: the UK government’s new visa rules, I’ve written about my own experience—spending more than £13,000 on visas and a ridiculous test that had incorrect answers—but also why I still love the UK, even as the government tried to deter me from living here. www.forkingpaths.co/p/my-life-in...

An excellent summary as to why early career scientists should publish in Society Journals. Please read it. journals.asm.org/doi/10.1128/...

Thrilled to see our Phage CRISPRi paper in @PLOSbiology doi.org/10.1371/jour...

So following up on Aude Bernheim’s preprint yesterday, we uploaded our related work on predictive phage therapy for uropathogenic E. coli. Our phage interactions for the predictive models are >9000 interactions in artificial urine…would be great to add more generalist phages…

Viruses of Microbes - UK (VoM - UK) 25th - 26th January 2024 www.northumbria.ac.uk/about-us/new...

A heritable iron memory enables decision-making in Escherichia coli

Going back to methods to generate heterogeneity - I always thought this paper by JJ Collins was overlooked (even though in Nature) - you just need the right interacting regulatory systems to generate a biphasic population: rdcu.be/dqEOZ

Similar can be achieved by subsets that express colanic acid that limits many phage interactions. We are looking at the interplay between levels of O157 antigen, Gp4 capsule and colanic acid expression for phage resistance in vivo. Basis to heterogeneity still to be determined……