In today’s spotlight, we’re highlighting a statement from the NIH detailing the recently announced Standardized Organoid Modeling (SOM) Center which is the first of its kind in the US. Read the full article here:

New ToxBlog by Rebecca Critser: World Congress on Alternative 13: A Critical Incubator for the Development of New Approach Methodologies Read the article here and let us know your thoughts in the comments below: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Dr. Paul Locke was featured in the recent documentary“How to make Drugs and Feel Great About Everything” which deals with the various issues surrounding Drug Development including New Approach Methodologies. Watch the full film here: vimeo.com/ondemand/htmd

In this entry of NAM 101, we’re going over In Chemico models. (1/4)

Team Leader Dr. Paul Locke was recently interviewed for a news story by the CBS Evening News discussing animal testing. Click the link here to watch the full video: youtu.be/k7_j-kyT1bU?...

Leader Dr. Paul Locke was quoted in this article written in collaboration with The Post and Courier alongside CBS News discussing the changing landscape of animal testing and the government's push to transition away from animal models. Read More here: www.postandcourier.com/news/special...

New ToxBlog by Sadie Jacobs: Professional Perspectives: A New Federal Bill Would Bring Government-Funded Animal Experiments Out of the Shadows. Were you at the briefing last week? Leave your thought down below. Link to the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Team members Loza Taye, Rebecca Critser, and Akosua Dufie wrote an article for The Enviromental Forum about the Loper Bright Enterprises v. Raimondo decision and its impact on federal agency’s ability advocate for regulation interpretation. Link: jhutoxicologypolicy.squarespace.com/s/locke.pdf

In this entry of the NAMs 101 series, we’re focusing on In Silico Models. These computer-based simulation models predict biological activity based on the molecular structure of a given chemical or substance. (1/5)

In this Friday spotlight we’re focusing on an article from McKinsey & Company discussing New Approach Methodologies in Drug development; making a case for NAMs being the future for drug development. Link to read article here: www.mckinsey.com/industries/l...

New ToxBlog by Paul Locke: Transitioning to Human-Centered Science: An Off-Ramp and Transition Plan Link to read further: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this entry of the NAMs 101 series, we’re looking at some examples of Microphysiological systems or MPS for short. (1/6)

In today’s Friday spotlight, we’re looking at an article by Hannah Robbins detailing the recent developments surrounding “whole brain” organoids. Link here to read further: engineering.jhu.edu/news/johns-h...

New #ToxBlog by Conley Wouters: Professional Perspectives: Wisconsin Court Orders Criminal Investigation of Beagle Breeder Ridglan Farms Link to blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this entry of the NAMs 101 series, we’re talking about the Monolayer. (1/4)

In today’s spotlight we’re looking at an article recapping ICARE’s World Laboratory Animals Day 2025 panel from April of this year. Link to read the article here: icareanimals.substack.com/p/world-labo...

New ToxBlog by Jo Anderson: From Option to Obligation: The Legal Imperative for NAMs Link to blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Today we’re starting our bi-weekly "NAMs 101" series going over the various types of NAMs that currently exist. To start with we’re doing a brief overview of some of the in-vitro methods that currently exist. (1/3) Next post will be out on August 20th and focus on Monolayers.

Today, we’re spotlighting an article from the NAMs Journal discussing the potential applications of New Approach Methodologies for assessing the genetic susceptibility towards Parkinson’s disease. Link to read the article here: www.sciencedirect.com/science/arti...

Starting next week, we’ll be starting a new bi-weekly series serving as a brief primer to the various types of New Approach Methodologies that exist currently and some of the agencies who make utilizing them possible.

New ToxBlog by Matthew Durthaler: A Bright Tomorrow for Therapeutic Orphans: The Potential for New Approach Methodologies to Bridge Data Gaps for Pregnant Patients Link to read here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In the final entry in the interview series, Dr. Paul Locke recalls a story about why decided to form Toxicology Policy Team Thank you to everyone who made these interviews possible.

In this spotlight, we’re looking at an article from Thomas Hartung discussing the impact that FDA’s decision to take away from animal testing in favor of new approach methodologies could affect the field Preclinical Testing. Link to read more here: www.genengnews.com/topics/artif...

(1/3) During a Workshop on reducing animal testing, Acting NIH Deputy Director Dr. Nicole Kleinstreuer announced that “all new funding opportunities will include language on the consideration of NAMs” and “will no longer seek out proposals that exclusively use animal models.”

Team member Rebecca Critser was recently a part of a panel discussing the legal solutions to problems surrounding the task of rehoming former laboratory animals. Link to full panel here: www.youtube.com/watch?v=UrYc...

New ToxBlog by Aaradhya Diwan: Our Tiny Allies in Toxicological Testing Part 2 – Transparent Roundworms as Alternative Models Link to read here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

There's been some confusion & misinformation about Monday's announcement that NIH will no longer seek proposals exclusively for animal models. In this new blog, I break down what it means, what it doesn't, & how it will impact animals in laboratories. 🧪 www.scienceadvancement.org/reflections/...

Dr. Locke was recently quoted in a recent article from by Hiroko Tabuchi of New Yorks Times discussing the EPA’s efforts to rehome animals from animal testing facilities. Link to article here: www.nytimes.com/2025/07/03/c...

In this entry in the interview series, we sat down with Dr. Anicca Harriot to discuss what her favorite aspects of the team were. Next interview will be released on July 23rd

In this early spotlight, we’re taking a look at a recent statement from the Animal Welfare Institute discussing the NIH and FDA decision to reduce the use animals in research and testing. Link to read further: awionline.org/press-releas...

New ToxBlog by Akosua Dufie and Jo Anderson: Unveiling IACUC members: "Triumph for rule of law and animal welfare or a dangerous precedent? A closer look at Poe 2 & 5 et al v University of Washington et al." Link to read further: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Reminder to tune in tomorrow at 3 PM EST to hear @rebecca-critser.bsky.social‬ and the other panelists discuss the legal solutions to the issues surrounding the task of rehoming former laboratory animals. Link to details and registration here: americanbar.zoom.us/webinar/regi...

In this latest interview, undergrad Shannon Dixon talks about some of her favorite aspects of the team and how she feels that influences with work that we do. Next interview will be out on July 9th.

Today we’re spotlighting an article by Bryan Polcyn discussing the work of the laboratory Stem Pharm in developing New Approach Methodologies such as neural organoids. Link to article to read further: www.fox6now.com/news/feds-pu...

Today we’re looking back at a panel from March of this year discussing the changing political landscape and how it would affect the efforts to reduce the use of animal models. Link to the full symposium here: youtu.be/vkhKhcCJdbo?...

Tune in on Thursday, June 26th to hear a panel of experts including team member Rebecca Critser as discuss legal solutions to the issues surrounding the task of rehoming former laboratory animals. Link for more details and registration here:

New ToxBlog by Shannon Dixon: The Silent Strain: Compassion Fatigue in Animal Research Labs Read more at www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In today’s interview, Breanne Kincaid talks about her work and the value the team’s ability to collaborate brings to our work. Next interview will be released on June 25th

Today we’re highlighting an article from the Karolinska Institutet discussing the benefits of using microphysiological systems (MPS) such as organoid “mini brains” and organ-on-a-chip over animal models. Link to read the article: news.ki.se/how-mini-org...

Today, we’re looking back at a panel presented by Yiguang Zhu and the Michigan State University's College of Law symposium. Link to full symposium here: youtu.be/XshD7ACEWf4?...

New ToxBlog by Zachary Liebowitz: NAMs and the Funding Frontier: How Modern Toxicology Maximizes Scientific Return on Investment Link: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this edition of our interview series with the team we have Zachary Liebowitz discussing what brought him to the team Next interview goes live on June 11th

Dr. Paul Locke was among those quoted in an article by Capitol Forum discussing FDA’s published roadmap detailing the transition to non-animal models for testing drug function and safety. Link below to read further: thecapitolforum.com/fdas-plan-to...

Today we’re highlighting an article by Rachel Fobar from Vox discussing nuances of the Trump administration's desire to end animal testing. Link below: www.vox.com/future-perfe...

We are saddened to hear about the passing of Rep. Gerry Connolly. Connolly was an invaluable advocate for both animal welfare and public health. He was committed to making world a better place. Our condolences to his family, peers, and constituents

Today we're looking back at a panel presented by team member Breanne Kincaid at the Michigan State University's College of Law symposium. Link to the full symposium: www.youtube.com/watch?v=XshD...

New ToxBlog by Yiguang Zhu: From Roadmap to Reality: Validating NAMs for FDA's Plan to Phase Out Animal Testing Link: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this entry of our interview series, we are seeing Yiguang Zhu discussing some of the work he’s done for his PhD and how it added to the larger international conversation surrounding NAMs Next Post out on May 28th, 2024

Dr. Locke was quoted in a recent article by Julia Musto of the independent discussing how the Trump Administration cuts to organizations such as HHS could affect the thousands of animals held in testing facilities across the US. Link to article here: www.independent.co.uk/news/health/...

If you aren’t familiar with @madelinekrasno.bsky.social work at @whenwejustify.bsky.social do yourself a favor and take a few minutes to read this recent article. They are doing amazing work on behalf of animals used in research by providing a safe space for scientists to connect ❤️