For those looking to learn more about non-animal alternatives, @pcrm.org and the @jhucaat.bsky.social are hosting a 4-day program introducing various new approach methodologies. Learn more here: www.pcrm.org/ethical-scie...

In today’s spotlight, we’re looking at a statement from FASEB discussing a panel that NASEM had regarding New Approach Methodologies. The article also links to the full panel discussion at end of the statement. Link to read further here: buff.ly/uiRZaGr

Happy Holidays from the ToxTeam We're taking a small break for the remainder of the year. We’ll be back with regular updates during the week of January 5th

New ToxBlog by CriShaun Hardy: Xenotransplantation: Clinical Progress and a Need for Regulation Read the Blog here: jhutoxicologypolicyresearch.org/tox-blog/blo... Have you read the blog? What are your thoughts on Xenotransplantation?

Dr. Paul Locke was recently on episode 988 of the @publichealthpod.bsky.social as a guest to discuss new approach methodologies and what regulators can do to take charge of the transition to these innovative methods. Link to the full episode here: publichealth.jhu.edu/headlines/pu...

Recently team had our final in person quarterly meeting for the year.once a quarter team members come from all over to meet at Bloomberg School of Public Health in Baltimore to discuss our priorities for the coming quarter as well as brainstorm new ideas to further our work (1/3)

In this Friday spotlight, we’re focusing on an article from Genetic Engineering and Biotechnology News discussing the work Diana Klein, PhD and the development of lung organoids for lung disease treatments. Read the article here: www.genengnews.com/topics/biopr...

Last Month, Team Member @rebecca-critser.bsky.social was among the 5 finalists for the Sommer Klag Advocacy Impact Awards. We on the team are proud of Rebecca for her presentation and making it as finalist. Watch the full presentation here: www.youtube.com/watch?v=W0Cy...

New ToxBlog by Richelle Romanchik: Environmental Health and Safety (EHS) in the Animal Industry Do you have thoughts on the blog? What do you think we can do to protect those working at biosafety labs? Link to article: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In today’s spotlight we’re focusing on an article from the New York Times about Brain Organoids. Do you have thoughts on the article? Let us know in the comments Link to article here: www.nytimes.com/2025/11/06/s...

New ToxBlog by Loza Taye: Reflections on “From Deference to Deliberation” Read the full ToxBlog here: jhutoxicologypolicyresearch.org/tox-blog/blo... Have you read the “From Deference to Deliberation?” Have thoughts on the ToxBlog? Leave them below in the comments

Starting Now

Reminder to tune this Wednesday

In this spotlight, we’re focusing on an article from FireceBiotech discussing U.S. Food and Drug Administration (FDA)’s approval for an organ on a chip platform for an Investigational New Drug (IND) application. Link to article here:

Reminder that next week, team member Rebecca Crister will be a part of the 2025 Sommer Klag Advocacy Impact Awards Lightning Pitch Competition. Follow the link here for more details: publichealth.jhu.edu/lerner-cente...

Known breeder of research dogs, Ridglan Farms, has agreed to stop selling research dogs among animal abuse allegations . If you want to know more about, Conley Wouters wrote a ToxBlog detailing the investigation surrounding the breeder earlier this year.

New ToxBlog by Daria Bednarczyk, Blair Eagleson, CriShaun Hardy, Akosua Dufie, Matthew Durthaler, Zachary Liebowitz, and Rebecca Critser: Reflecting on the 33rd Animal Law Conference Link blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Paul Locke recently spoke alongside @pcrm.org's Ryan Merkley, Sally Christopher and student Jackie Myers in support of Michigan State Bill 4254, also known as Queenie’s Law. Below is a snippet from Dr. Locke’s written testimony which you can read here: buff.ly/gZW6RAT

Today we’re highlighting an article from Nature discussing New Approach Methods (NAMs) and the changing landscape surrounding them. Read the article here: www.nature.com/articles/d41... What are your thoughts on the article? Let us know in the comments

Over this last weekend, members of the Toxicology Policy Team attended the annual Animal Law Conference. Congrats to Rebecca Critser, Zachary Liebowitz, Akosua Dufie, Cris Hardy, Blair Eagleson, Daria Bednarczyk, Shannon Dixon, and Matthew Durthaler on being able to attend

We’re happy to announce that the ToxTeam’s own Rebecca Critser has been nominated as a finalist for Sommer Klag Advocacy Impact Awards. Find more information about the event here: publichealth.jhu.edu/lerner-cente...

New Toxblog by Awurakua Asamoah-Mensah: AOPs, Space, and In-Silico Read the blog post here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... Have thoughts on the new Toxblog? Leave them in the comments below

Lewis and Clark are offering a full tuition scholarship for LLM and MSL students who have an interest in advancing anti-vivisection work through policy, education, or advocacy. Check out the details of scholarship at the link here: animallawonline.lclark.edu

In this final NAMs 101 posts, we’re discussing the omics. These analytical technologies are used to study biomolecular and molecular processes of a given organism. (1/3)

In today’s spotlight, we’re highlighting a statement from the NIH detailing the recently announced Standardized Organoid Modeling (SOM) Center which is the first of its kind in the US. Read the full article here:

New ToxBlog by Rebecca Critser: World Congress on Alternative 13: A Critical Incubator for the Development of New Approach Methodologies Read the article here and let us know your thoughts in the comments below: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Dr. Paul Locke was featured in the recent documentary“How to make Drugs and Feel Great About Everything” which deals with the various issues surrounding Drug Development including New Approach Methodologies. Watch the full film here: vimeo.com/ondemand/htmd

In this entry of NAM 101, we’re going over In Chemico models. (1/4)

Team Leader Dr. Paul Locke was recently interviewed for a news story by the CBS Evening News discussing animal testing. Click the link here to watch the full video: youtu.be/k7_j-kyT1bU?...

Leader Dr. Paul Locke was quoted in this article written in collaboration with The Post and Courier alongside CBS News discussing the changing landscape of animal testing and the government's push to transition away from animal models. Read More here: www.postandcourier.com/news/special...

New ToxBlog by Sadie Jacobs: Professional Perspectives: A New Federal Bill Would Bring Government-Funded Animal Experiments Out of the Shadows. Were you at the briefing last week? Leave your thought down below. Link to the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Team members Loza Taye, Rebecca Critser, and Akosua Dufie wrote an article for The Enviromental Forum about the Loper Bright Enterprises v. Raimondo decision and its impact on federal agency’s ability advocate for regulation interpretation. Link: jhutoxicologypolicy.squarespace.com/s/locke.pdf

In this entry of the NAMs 101 series, we’re focusing on In Silico Models. These computer-based simulation models predict biological activity based on the molecular structure of a given chemical or substance. (1/5)

In this Friday spotlight we’re focusing on an article from McKinsey & Company discussing New Approach Methodologies in Drug development; making a case for NAMs being the future for drug development. Link to read article here: www.mckinsey.com/industries/l...

New ToxBlog by Paul Locke: Transitioning to Human-Centered Science: An Off-Ramp and Transition Plan Link to read further: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this entry of the NAMs 101 series, we’re looking at some examples of Microphysiological systems or MPS for short. (1/6)

In today’s Friday spotlight, we’re looking at an article by Hannah Robbins detailing the recent developments surrounding “whole brain” organoids. Link here to read further: engineering.jhu.edu/news/johns-h...

New #ToxBlog by Conley Wouters: Professional Perspectives: Wisconsin Court Orders Criminal Investigation of Beagle Breeder Ridglan Farms Link to blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In this entry of the NAMs 101 series, we’re talking about the Monolayer. (1/4)

In today’s spotlight we’re looking at an article recapping ICARE’s World Laboratory Animals Day 2025 panel from April of this year. Link to read the article here: icareanimals.substack.com/p/world-labo...

New ToxBlog by Jo Anderson: From Option to Obligation: The Legal Imperative for NAMs Link to blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

Today we’re starting our bi-weekly "NAMs 101" series going over the various types of NAMs that currently exist. To start with we’re doing a brief overview of some of the in-vitro methods that currently exist. (1/3) Next post will be out on August 20th and focus on Monolayers.

Today, we’re spotlighting an article from the NAMs Journal discussing the potential applications of New Approach Methodologies for assessing the genetic susceptibility towards Parkinson’s disease. Link to read the article here: www.sciencedirect.com/science/arti...

Starting next week, we’ll be starting a new bi-weekly series serving as a brief primer to the various types of New Approach Methodologies that exist currently and some of the agencies who make utilizing them possible.

New ToxBlog by Matthew Durthaler: A Bright Tomorrow for Therapeutic Orphans: The Potential for New Approach Methodologies to Bridge Data Gaps for Pregnant Patients Link to read here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...

In the final entry in the interview series, Dr. Paul Locke recalls a story about why decided to form Toxicology Policy Team Thank you to everyone who made these interviews possible.

In this spotlight, we’re looking at an article from Thomas Hartung discussing the impact that FDA’s decision to take away from animal testing in favor of new approach methodologies could affect the field Preclinical Testing. Link to read more here: www.genengnews.com/topics/artif...

(1/3) During a Workshop on reducing animal testing, Acting NIH Deputy Director Dr. Nicole Kleinstreuer announced that “all new funding opportunities will include language on the consideration of NAMs” and “will no longer seek out proposals that exclusively use animal models.”

Team member Rebecca Critser was recently a part of a panel discussing the legal solutions to problems surrounding the task of rehoming former laboratory animals. Link to full panel here: www.youtube.com/watch?v=UrYc...

New ToxBlog by Aaradhya Diwan: Our Tiny Allies in Toxicological Testing Part 2 – Transparent Roundworms as Alternative Models Link to read here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...