Adam Broerman
@adambroerman.bsky.social
📤 170
📥 36
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Dynamic protein designer
@uwproteindesign.bsky.social
pinned post!
Excited to join here and announce our new
#proteindesign
strategy for allosterically controlling the kinetics of protein-protein interactions! Read on for cool applications in cytokine signaling, biosensing, and protein circuits.
12 months ago
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reposted by
Adam Broerman
Joanna Slusky
12 months ago
If deposition becomes the norm in the field so much information will be unlocked.
add a skeleton here at some point
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reposted by
Adam Broerman
Gaurav Bhardwaj
12 months ago
Super excited to share the latest preprint from our lab on macrocycle binder design! Skeetorial (or whatever they are called) to follow soon. Thanks to all the amazing collaborators!
www.biorxiv.org/content/10.1...
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Accurate de novo design of high-affinity protein binding macrocycles using deep learning
The development of macrocyclic binders to therapeutic proteins has typically relied on large-scale screening methods that are resource-intensive and provide little control over binding mode. Despite c...
https://www.biorxiv.org/content/10.1101/2024.11.18.622547v1
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Excited to join here and announce our new
#proteindesign
strategy for allosterically controlling the kinetics of protein-protein interactions! Read on for cool applications in cytokine signaling, biosensing, and protein circuits.
12 months ago
2
30
12
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