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Online now! A piperidinyl amide compound enhances Ca2+ signaling in cardiomyocytes by increasing activity of Ca2+ pump. Elisa Bovo, Roman Nikolaienko, Samantha L. Yuen, Catherine A. Makarewich, Marzena Brinkmann, David D. Thomas, Robyn T. Rebbeck, and Aleksey V. Zima. www.cell.com/biophysrepor...

Online now! Computational Perspectives on Tubulin E-hook Structure and Mechanisms. Alexander C. Bromley and Dana N. Reinemann. www.cell.com/biophysrepor...

Online now! Effect of Hemodynamic on Clot Formation and Flow Cessation in Patient-Specific Coronary Bifurcations. Mohammad Rezaei and Bahar Firoozabadi. www.cell.com/biophysrepor...

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Online now! Photoelectrical modulation of Apoptosis and Autophagy via Voltage-Gated Ion Channels and Mitochondrial ROS: A mechanistic insight study of the role of VGICs, by Mohammad Mohammadiaria. www.cell.com/biophysrepor...

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Online now! Menthol Disruptive Effects on Kanamycin-Resistant Escherichia coli Energy Metabolism and Ion Fluxes. Silvard Tadevosyan, Siranuysh Grabska, Hovakim Grabski, Ruben Abagyan, Karen Trchounian, and Naira Sahakyan. www.cell.com/biophysrepor...

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Check out an article from our most read list: "Engineering stress as a motivation for filamentous virus morphology" (Andrew McMahon et. al.)

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Online now! Optimizing a Coarse-Grained Model for Large-Scale Membrane Protein Simulation. Chen Yun Wen, Yun Lyna Luo, and Jesper J. Madsen.

Online now! Optimizing a Coarse-Grained Model for Large-Scale Membrane Protein Simulation. Chen Yun Wen, Yun Lyna Luo, and Jesper J. Madsen. www.cell.com/biophysrepor...

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Online now! Sequence and supercoiling-dependent effects on the structural dynamics of DNA minicircle. Manuel Micheloni, Luca Tubiana, Raffaello Potestio, and Lorenzo Petrolli.

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Online now! An Antarctic toothfish eye lens protein resists thermal stress even when extensively deamidated. Collin Sroge, Vanessa Encinas, Zane G. Long, Rayhan Fauzi Said Bawahab, Thomas Cao, Amanda Abiad, Rachel W. Martin.

Online now! Refractive index as an indicator for dynamic protein condensation in cell nuclei. Orlando Marin, Peter Kirchweger, Arina Dalaloyan, Yoav Barak, and Michael Elbaum.

Online now! Refractive index as an indicator for dynamic protein condensation in cell nuclei. Orlando Marin, Peter Kirchweger, Arina Dalaloyan, Yoav Barak, and Michael Elbaum. www.cell.com/biophysrepor...

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Online now! Dual-view microscopy of single-molecule dipole orientations. Yonglei Sun and Quan Wang. www.cell.com/biophysrepor...

Check out an article from our most read list: "CD spectra reveal the state of G-quadruplexes and i-motifs in repeated and other DNA sequences" (Levi Diggins et al.)

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Check out an article from our most read list: "Single-molecule localization microscopy error is sensor dependent and larger than theory predicts" (Alfonso Brenlla et. al.)

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at buff.ly/fkiDDQg.

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at www.biophysics.org/blog/call-for-applications-editor-in-chief-of-biophysical-journal.

Biophysical Journal seeks candidates to be its next Editor-in-Chief beginning in 2027. Applications and nominations will be accepted until March 1. More information is available at www.biophysics.org/blog/call-for-applications-editor-in-chief-of-biophysical-journal.

Engage with editors who are active researchers in the community and who are experts in their field. Learn more about the members of our editorial board:

Platelets feel the squeeze. Rodriguez et al. use optical microscopy, scanning ion conductance microscopy and microcontact printing to mimic narrow vessels in vitro, revealing how spatial confinement alters platelet shape, spreading dynamics, and mechanics.