I wrote a bit about practical considerations for using #cryo-ET labels and some things to work on if we want to find any protein in any cell. authors.elsevier.com/a/1mA6h,LqAr...

Out today, we can now multiplex receptor mapping at synapses thanks to a dimeric gold nanoparticle label optimized by Hoyoung that's distinguishable from monomers! Dimeric gold nanoparticles enable multiplexed labeling in cryoelectron tomography | PNAS www.pnas.org/doi/10.1073/...

Excited to share the final version of this work from the group, led by Chengli! Always fun when an unexpected complex appears in a cryo-EM dataset 😀 rdcu.be/eym9v

I've been lucky to be able to work with Natalie on producing several new monoclonal antibodies using these methods, with great success! Check out our group's new protocols paper on how to generate mAbs for various membrane proteins - currentprotocols.onlinelibrary.wiley.com/doi/full/10....

So glad to see this out! Congrats!

Having a great week so far at #BPS2025!

Congrats Makayla!

Gotta love finding soccer balls in tomograms ⚽ 😂

Loving the holiday spirit at PNCC to start off December 🎄 + early Xmas gift getting to test out Tomo5!

First Bluesky post! Our recent eLife paper is now an official version of record. This was my first project using #Cryo-ET and I'm definitely hooked - it's so fun to look at snapshots of synapses within brain tissue and see individual proteins. Excited to share more soon! doi.org/10.7554/eLif...