Sort of supports David Epstein's "Range" hypothesis: en.wikipedia.org/wiki/Range:_...

This is the most interesting thing I've seen in ages. If intra-cellular membrane-less hydrogen ion gradients are biologically meaningful/useful things then so too might be membrane-less gradients of everything else - from bigger ions with discrete point-sources through protein complexes.

Seems like the BBC is going all in on a self-abusive resolution to make 2025 their shittest year ever. WTF is going on over there? Are they alight? Its like seeing a once beloved and often hilariously witty uncle turn into a stupidly boring and hateful racist after they have a stroke.

Are they saying that the high IQs of all the Einsteins and Newtons, the out-of-the-box-thinking "disruptor" people and all other nerds with autism spectrum diagnoses, are attributable to their moms taking Tylenol while pregnant? Should I buy shares in whatever company makes Tylenol? I'm so confused.

I've occasionally travelled to the USA for the past ~20 years (maybe 15 times total if you include transits via US cities). On every trip, at every level of interaction with travel officials, I have felt unusually unwelcome. Is that an uncommon experience?

OK so the ASM is admitting (1) to being worried about losing money provided by the US federal gvt (their perceived overlords) if they do the right thing, and (2) that they also don't want the bother of dealing with the hypothetical legal consequences of doing the right thing? So bad.

How about no. We ain't scrubbing nothing.

Condolences to all impacted by this. Research scientists everywhere should reflect on how fragile this funding stream has always been, adapt our future research strategies to account for that reality, and wean ourselves off of our dependency on the NIH and other similarly fickle agencies/systems...

Fantastic thread where Ryan explores the potential selective advantages of some not-so-silent synonymous substitutions that have convergently appeared in multiple different SARS-CoV-2 lineages. Includes cool ideas on how some of these mutations might contribute to immune evasion.