Tianrun Jerry Li
@jerrytli.bsky.social
π€ 26
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PhD in Plant pathology, UC Davis
reposted by
Tianrun Jerry Li
Ellen Rim
3 months ago
Really excited to join Stanford ChemE this September! We'll engineer proteins in plant immune and hormone pathways, combining high-throughput directed evolution with ML. Our goal is to enhance climate stress resilience and disease resistance in crops:
rim.stanford.edu
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Harnessing synthetic biology to engineer resilient crops
https://rim.stanford.edu
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Iβm honored to share the illustration accompanying our receptor engineering paper in Nature Plants. Created by the talented Phoebe Sinner from the Coaker lab, this artwork elegantly highlights how natural diversity contributes to differences in receptor specificity.
www.nature.com/articles/s41...
3 months ago
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Happy to share that the last piece of my thesis is finally out! Here, we designed and delivered a dual PRR stack in potato to control vector-borne and soil-borne bacterial pathogens, Ca. Liberibacter solanacearum and Ralstonia solanacearum.
onlinelibrary.wiley.com/doi/10.1111/...
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Introducing Pattern Recognition Receptors in Potato Confers Enhanced Resistance to Ralstonia solanacearum but Not a Vector Borne Pathogen
Click on the article title to read more.
https://onlinelibrary.wiley.com/doi/10.1111/pbi.70268
3 months ago
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Itβs my great honor to be part of this project and happy to see this part of my thesis work finally out in Nature Plants!
add a skeleton here at some point
4 months ago
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reposted by
Tianrun Jerry Li
Dani Stevens, Ph.D.
4 months ago
#2025ISMPMI
π£ In silico screening of PRR-epitope interactions is now possible! Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! ππ± Small π§΅
www.biorxiv.org/content/10.1...
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mamp-ml: A deep learning approach to epitope immunogenicity in plants
Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...
https://www.biorxiv.org/content/10.1101/2025.07.11.664399v1
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