Hot article by Donghui Wei 𝘦𝘵 𝘢𝘭. #ZhengzhouUniversity This theoretical study employs DFT to investigate the possible mechanisms of #NHC-catalyzed asymmetric cycloadditions between hydrazones and isatins, including [4 + 2] and [3 + 2] cycloadditions. doi.org/10.1039/D5QO01408E

#Review article by Gabriel P. da Costa 𝘦𝘵 𝘢𝘭. #FURG This review highlights the progress of the synthesis of alkynyl sulfones and alkynyl chalcogen derivatives during the last ten years. doi.org/10.1039/D5QO01359C

#Review article by Shaojie Lou This review summarizes chiral directing groups in transition-metal-catalyzed asymmetric C–H activation since 2005, their roles in catalysis, and key reaction mechanisms. doi.org/10.1039/D5QO01354B

#OpenAccess research by Esteban Mejía 𝘦𝘵 𝘢𝘭. #LIKAT Authors synthesised and characterised a series of 5,10-dihydrophenazine derivatives that bear heterocycles as electron-withdrawing groups. doi.org/10.1039/D5QO01348H

Hot research by Xuesen Fan 𝘦𝘵 𝘢𝘭. Authors present a novel synthesis of benzodiazepine-containing polyheterocyclic compounds. Check out if you are interested. doi.org/10.1039/D5QO01332A

Hot article by Zhenda Tan 𝘦𝘵 𝘢𝘭. #HainanUniversity This review examines radical-mediated C–O bond scission strategies in photoredox systems, elucidating the generation mechanisms and transformation patterns of radical intermediates across distinct reaction pathways. doi.org/10.1039/D5QO01215E

#OpenAccess article by Vidya Kumaria and Lokman H. Choudhury. #IITPatna Authors report a novel Rh(III)-catalyzed perimidine-directed C–H activation strategy for the synthesis of perimidine-fused heterocycles using various types of alkenes. 🔗 doi.org/10.1039/D5QO01292A

🔥Hot research by Hao Song 𝘦𝘵 𝘢𝘭. #SichuanUniversity Authors report a chiral phosphoric acid-catalyzed enantioselective synthesis of spiro-bicyclo[2.1.1]hexanes featuring vicinal tertiary–quaternary stereocenters. 🔗 doi.org/10.1039/D5QO01029B

🎉Issue 23 of OCF is released now, please check out the cover article： 𝐏𝐝-𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐞𝐝 𝐟𝐥𝐨𝐰 𝐓𝐬𝐮𝐣𝐢–𝐓𝐫𝐨𝐬𝐭 𝐚𝐥𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐩𝐡𝐞𝐧𝐨𝐥𝐬: 𝐜𝐨𝐧𝐭𝐢𝐧𝐮𝐨𝐮𝐬-𝐟𝐥𝐨𝐰, 𝐞𝐱𝐭𝐫𝐚𝐜𝐭𝐢𝐨𝐧-𝐟𝐫𝐞𝐞 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐨𝐟 𝐞𝐬𝐦𝐨𝐥𝐨𝐥 𝐯𝐢𝐚 𝐚𝐥𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐞𝐩𝐨𝐱𝐢𝐝𝐚𝐭𝐢𝐨𝐧, 𝐚𝐧𝐝 𝐚𝐦𝐢𝐧𝐨𝐥𝐲𝐬𝐢𝐬 by Shū Kobayashi 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO01336D

#OpenAccess article by Sharanappa Nembenna 𝘦𝘵 𝘢𝘭. #NISER The protocol introduces the first examples of nitrile and isocyanide reduction 𝘷𝘪𝘢 a substrate-assisted pathway. 🔗 doi.org/10.1039/D5QO01184A

Outstanding contributions take place every day across the chemical sciences. #RSCPrizes are your chance to recognise that work. Nominations are open now across a wide range of categories 👉 Make your nomination here: https://rsc.li/43w1Oaq #ChemSky

#OpenAccess article by Juan R. Granja 𝘦𝘵 𝘢𝘭. #CiQUS #USC A new class of supramolecular #antimicrobials from D,L-cyclic #peptides with a dihydroxylated-γ-residue mimicking saccharides is described. 🔗 doi.org/10.1039/D5QO01374G

#OpenAccess article by Ronald K. Castellano 𝘦𝘵 𝘢𝘭. #UniversityofFlorida #UF The current work introduces a novel photoswitch system combining an electron-rich [2.2]pCp moiety with an electron-deficient RCN unit, as a planar chiral “push–pull” architecture. 🔗 doi.org/10.1039/D5QO01401H

#Review article by Keshaba Nanda Parida 𝘦𝘵 𝘢𝘭. #CSIR-NIIST This perspective reviews recent advances in #OICs as sources of iodoarenes and oxidative reagents, focusing on transition metal-free protocols, mechanistic insights, and synthetic applications since 2019. 🔗 doi.org/10.1039/D5QO01262G

#Review article by Satish Kumar Singh 𝘦𝘵 𝘢𝘭. #GEC Daman This review outlines progress in mechanistic understanding and catalyst design for visible-light-driven CDC reactions of N-heterocycles between 2014 and 2025. 🔗 doi.org/10.1039/D5QO01346A

🔓 #OpenAccess article by Cristiano Zonta 𝘦𝘵 𝘢𝘭. #UNIPD This study presents an innovative approach for rapid and reliable determination of circular dichroism outputs using a chiroptical supramolecular sensor based on an oxo-vanadium(V) complex. 🔗 doi.org/10.1039/D5QO01281C

🔥Hot article by Qiang Xiao 𝘦𝘵 𝘢𝘭. #JXSTNU Authors report a novel electroreductive intermolecular 1,2-thiocarboxylation of alkenes with cyclosulfonium salts and carbon dioxide (CO₂) via selective C–S bond cleavage for the construction of thioether acids. 🔗 doi.org/10.1039/D5QO01313E

🔓 #OpenAccess article by Radim Hrdina 𝘦𝘵 𝘢𝘭. #CUNI Authors disclose the use of Burgess reagent in a ring-contraction of pre-functionalised 2-amino-adamantan-1-ols to noradamantyl carbaldehydes in a pinacol-type rearrangement. 🔗 doi.org/10.1039/D5QO01150G

🎉Issue 22 of Organic Chemistry Frontiers has been released! Read the cover article by Mitsuhiro Arisawa 𝘦𝘵 𝘢𝘭 🔗 doi.org/10.1039/D5QO01123J

🔥𝐂𝐫𝐨𝐬𝐬-𝐝𝐞𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧𝐚𝐭𝐢𝐯𝐞 𝐂–𝐎 𝐜𝐨𝐮𝐩𝐥𝐢𝐧𝐠 𝐨𝐟 𝐨𝐱𝐢𝐦𝐞𝐬 𝐰𝐢𝐭𝐡 𝐡𝐲𝐝𝐫𝐚𝐳𝐨𝐧𝐞𝐬: 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐨𝐟 𝐟𝐮𝐧𝐠𝐢𝐜𝐢𝐝𝐚𝐥 𝐚𝐳𝐨-𝐨𝐱𝐢𝐦𝐞 𝐞𝐭𝐡𝐞𝐫𝐬 by Alexander O. Terent'ev 𝘦𝘵 𝘢𝘭. The cross-dehydrogenative coupling ( #CDC) of oximes with hydrazones employing KMnO₄ as the oxidant was discovered. 🔗 doi.org/10.1039/D5QO01151E

🤔𝐀𝐫𝐞 𝐍-𝐡𝐞𝐭𝐞𝐫𝐨𝐜𝐲𝐜𝐥𝐢𝐜 𝐜𝐚𝐫𝐛𝐞𝐧𝐞 𝐫𝐚𝐝𝐢𝐜𝐚𝐥 𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐫𝐞𝐥𝐞𝐯𝐚𝐧𝐭 𝐢𝐧𝐭𝐞𝐫𝐦𝐞𝐝𝐢𝐚𝐭𝐞𝐬 𝐢𝐧 𝐫𝐚𝐝𝐢𝐜𝐚𝐥 𝐭𝐫𝐚𝐧𝐬𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧𝐬? Read article by David Martin 𝘦𝘵 𝘢𝘭. 🤫Authors show that NHC radical cations are unlikely to be the relevant intermediates in most NHC-promoted radical reactions. 🔗 doi.org/10.1039/D5QO01285F

🔥 𝐒𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐨𝐟 𝐜𝐡𝐢𝐫𝐚𝐥 𝐬𝐩𝐢𝐫𝐨-𝐡𝐞𝐭𝐞𝐫𝐨𝐜𝐲𝐜𝐥𝐢𝐜 𝐚𝐳𝐢𝐝𝐞𝐬 𝐯𝐢𝐚 𝐚𝐬𝐲𝐦𝐦𝐞𝐭𝐫𝐢𝐜 [𝟒 + 𝟐]-𝐜𝐲𝐜𝐥𝐨𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧 𝐨𝐟 𝐜𝐨𝐧𝐣𝐮𝐠𝐚𝐭𝐞𝐝 𝐯𝐢𝐧𝐲𝐥 𝐚𝐳𝐢𝐝𝐞𝐬 by Xiaoming Feng 𝘦𝘵 𝘢𝘭. Authors achieved highly selective [4+2]-cycloaddition of azidovinyl-cyclohexene with aurones and alkenyloxindoles here. 🔗 doi.org/10.1039/D5QO01290B

👉𝐃𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲-𝐨𝐫𝐢𝐞𝐧𝐭𝐞𝐝 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐨𝐟 𝐩𝐨𝐥𝐲-𝐬𝐮𝐛𝐬𝐭𝐢𝐭𝐮𝐭𝐞𝐝 𝐛𝐞𝐧𝐳𝐨𝐟𝐮𝐫𝐚𝐧 𝐝𝐞𝐫𝐢𝐯𝐚𝐭𝐢𝐯𝐞𝐬 𝐛𝐞𝐚𝐫𝐢𝐧𝐠 𝐚𝐦𝐢𝐧𝐨 𝐠𝐫𝐨𝐮𝐩𝐬 𝐚𝐭 𝟐- 𝐨𝐫 𝟑-𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧𝐬: 𝐑𝐡- 𝐨𝐫 𝐍𝐢-𝐜𝐚𝐭𝐚𝐥𝐲𝐳𝐞𝐝 𝐜𝐲𝐜𝐥𝐨𝐢𝐬𝐨𝐦𝐞𝐫𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐛𝐞𝐭𝐰𝐞𝐞𝐧 𝐲𝐧𝐚𝐦𝐢𝐝𝐞𝐬 𝐚𝐧𝐝 𝐞𝐧𝐨𝐥 𝐞𝐭𝐡𝐞𝐫𝐬 by Mitsuhiro Arisawa 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QI01247C

👉𝐏𝐫𝐞𝐜𝐢𝐩𝐢𝐭𝐚𝐭𝐢𝐨𝐧-𝐝𝐫𝐢𝐯𝐞𝐧 𝐝𝐢𝐚𝐬𝐭𝐞𝐫𝐞𝐨- 𝐚𝐧𝐝 𝐫𝐞𝐠𝐢𝐨𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐦𝐚𝐜𝐫𝐨𝐜𝐲𝐜𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐯𝐢𝐚 𝐛𝐞𝐧𝐳𝐨𝐢𝐧 𝐜𝐨𝐧𝐝𝐞𝐧𝐬𝐚𝐭𝐢𝐨𝐧: 𝐞𝐟𝐟𝐞𝐜𝐭𝐬 𝐨𝐟 𝐬𝐨𝐥𝐯𝐞𝐧𝐭𝐬 𝐚𝐧𝐝 𝐚𝐥𝐤𝐲𝐥 𝐜𝐡𝐚𝐢𝐧 𝐥𝐞𝐧𝐠𝐭𝐡𝐬 by Kosuke Ono 𝘦𝘵 𝘢𝘭. The benzoin condensation of a designed dialdehyde 1 with a terphenyl framework was investigated. 🔗 doi.org/10.1039/D5QO01179E

🔓𝐌𝐨𝐧𝐨𝐝𝐞𝐧𝐭𝐚𝐭𝐞 𝐡𝐚𝐥𝐨𝐠𝐞𝐧 𝐛𝐨𝐧𝐝 𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐚𝐳𝐢𝐫𝐢𝐝𝐢𝐧𝐞𝐬 𝐢𝐧 𝐟𝐨𝐫𝐦𝐚𝐥 [𝟑 + 𝟐] 𝐜𝐲𝐜𝐥𝐨𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧𝐬 by Boris J. Nachtsheim 𝘦𝘵 𝘢𝘭. Authors demonstrate that N-heterocyclic iodonium salts can catalyze [3+2] cycloadditions of aziridines through a monodentate halogen bond activation. 🔗 doi.org/10.1039/D5QO01119A

🔓𝐄𝐧𝐚𝐧𝐭𝐢𝐨𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐨𝐫𝐠𝐚𝐧𝐨𝐜𝐚𝐭𝐚𝐥𝐲𝐭𝐢𝐜 𝐞𝐥𝐞𝐜𝐭𝐫𝐨𝐜𝐡𝐞𝐦𝐢𝐜𝐚𝐥 α-𝐜𝐡𝐥𝐨𝐫𝐢𝐧𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐚𝐥𝐝𝐞𝐡𝐲𝐝𝐞𝐬 by Maurizio Benaglia 𝘦𝘵 𝘢𝘭. Enantioselective organocatalytic α-chlorination of aldehydes via electrochemical activation of the enamine intermediate through a SOMO strategy was investigated. 🔗 doi.org/10.1039/D5QO01249J

Issue 21 is online now! Check out our cover article: 𝐒𝐮𝐛-𝐫𝐨𝐨𝐦 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐭𝐫𝐚𝐧𝐬𝐟𝐞𝐫 𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 α,β-𝐮𝐧𝐬𝐚𝐭𝐮𝐫𝐚𝐭𝐞𝐝 𝐤𝐞𝐭𝐨𝐧𝐞𝐬 𝐮𝐬𝐢𝐧𝐠 𝐦𝐞𝐭𝐡𝐚𝐧𝐨𝐥 𝐚𝐬 𝐚 𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧 𝐬𝐨𝐮𝐫𝐜𝐞 by Sanjay Pratihar 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO01133G

🔓 #OpenAccess 𝐏𝐡𝐨𝐭𝐨𝐬𝐰𝐢𝐭𝐜𝐡𝐚𝐛𝐥𝐞 𝐚𝐧𝐢𝐨𝐧 𝐫𝐞𝐜𝐨𝐠𝐧𝐢𝐭𝐢𝐨𝐧 𝐯𝐢𝐚 𝐬𝐲𝐧𝐞𝐫𝐠𝐲 𝐛𝐞𝐭𝐰𝐞𝐞𝐧 𝐜𝐡𝐚𝐥𝐜𝐨𝐠𝐞𝐧 𝐛𝐨𝐧𝐝𝐢𝐧𝐠 𝐚𝐧𝐝 𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧 𝐛𝐨𝐧𝐝𝐢𝐧𝐠 by Lei You 𝘦𝘵 𝘢𝘭. Authors report light-responsive hydrazone-based receptors for photoswitchable anion binding. 🔗 doi.org/10.1039/D5QO01341K

👉𝐑𝐞𝐜𝐞𝐧𝐭 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐬 𝐢𝐧 𝐭𝐡𝐞 𝐢𝐧𝐭𝐞𝐫𝐦𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧 𝐨𝐟 𝐜𝐚𝐫𝐛𝐨𝐧𝐲𝐥𝐨𝐱𝐲 𝐫𝐚𝐝𝐢𝐜𝐚𝐥𝐬 𝐭𝐨 𝐚𝐥𝐤𝐞𝐧𝐞𝐬 by Zhiping Li 𝘦𝘵 𝘢𝘭. Authors summarize recent progress in the intermolecular addition of ArOCOO• and ROCOO• radicals to C=C through different precursors of carbonyloxy radicals. 🔗 doi.org/10.1039/D5QO01045D

🎉OCF Early Career Advisory board member 𝐗𝐢𝐚𝐨 𝐒𝐡𝐞𝐧 has been awarded with 𝐑𝐒𝐂 𝐅𝐥𝐮𝐨𝐫𝐢𝐧𝐞 𝐏𝐫𝐢𝐳𝐞! Find detailed information here: www.rsc.org/standards-an... And learn about 𝐑𝐒𝐂 𝐅𝐥𝐮𝐨𝐫𝐢𝐧𝐞 𝐏𝐫𝐢𝐳𝐞 here: www.rsc.org/standards-an...

👉OCF is involved in an RSC cross-journal themed collection Celebrating 200 Years of Benzene, guest edited by Ben Feringa @feringalab.bsky.social & Nazario Martin. Detailed information could be found here: 🔗 www.rsc.org/publishing/j...

📢We are delighted to announce a #OpenCall for papers to the RSC cross-journal themed collection Celebrating 200 Years of Benzene, guest edited by Ben Feringa @feringalab.bsky.social & Nazario Martin! Find out more about the collection and how to submit here🔽 www.rsc.org/publishing/j...

👉𝟏,𝟔-𝐇𝐲𝐝𝐫𝐨𝐬𝐮𝐥𝐟𝐨𝐧𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐩-𝐪𝐮𝐢𝐧𝐨𝐧𝐞 𝐦𝐞𝐭𝐡𝐢𝐝𝐞𝐬 𝐞𝐧𝐚𝐛𝐥𝐞𝐝 𝐯𝐢𝐚 𝐬𝐭𝐫𝐚𝐢𝐧-𝐫𝐞𝐥𝐞𝐚𝐬𝐞/­𝐚𝐫𝐨𝐦𝐚𝐭𝐢𝐜𝐢𝐭𝐲-𝐝𝐫𝐢𝐯𝐞𝐧 𝐚𝐥𝐤𝐲𝐥 𝐫𝐚𝐝𝐢𝐜𝐚𝐥 𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐒𝐎₂ 𝐜𝐚𝐩𝐭𝐮𝐫𝐞: 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐚𝐧𝐝 𝐚𝐧𝐭𝐢𝐩𝐫𝐨𝐥𝐢𝐟𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐬𝐭𝐮𝐝𝐢𝐞𝐬 𝐨𝐟 𝐬𝐮𝐥𝐟𝐨𝐧𝐲𝐥𝐚𝐭𝐞𝐝 𝐝𝐢𝐚𝐫𝐲𝐥𝐦𝐞𝐭𝐡𝐚𝐧𝐞𝐬 by Tabrez Khan 𝘦𝘵 𝘢𝘭. 🔓 #OpenAccess 🔗 doi.org/10.1039/D5QO00981B

🔥 𝐑𝐞𝐠𝐢𝐨𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐧𝐚𝐩𝐡𝐭𝐡𝐨[𝟐,𝟏-𝐛]𝐬𝐞𝐥𝐞𝐧𝐨𝐩𝐡𝐞𝐧𝐞𝐬 𝐯𝐢𝐚 𝐜𝐚𝐬𝐜𝐚𝐝𝐞 𝐜𝐲𝐜𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝟏,𝟑-𝐝𝐢𝐲𝐧𝐲𝐥𝐩𝐫𝐨𝐩𝐚𝐫𝐠𝐲𝐥 𝐚𝐥𝐜𝐨𝐡𝐨𝐥𝐬 𝐩𝐫𝐨𝐦𝐨𝐭𝐞𝐝 𝐛𝐲 𝐢𝐫𝐨𝐧(𝐢𝐢𝐢) 𝐜𝐡𝐥𝐨𝐫𝐢𝐝𝐞 𝐚𝐧𝐝 𝐝𝐢𝐨𝐫𝐠𝐚𝐧𝐲𝐥 𝐝𝐢𝐬𝐞𝐥𝐞𝐧𝐢𝐝𝐞𝐬 by Gilson Zeni 𝘦𝘵 𝘢𝘭. #selenium #heterocycles #cascade #FeCl3 🔗 doi.org/10.1039/D5QO01195G

👉 𝐑𝐡𝐨𝐝𝐢𝐮𝐦-𝐜𝐚𝐭𝐚𝐥𝐲𝐳𝐞𝐝 𝐜𝐲𝐜𝐥𝐨𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧 𝐨𝐟 𝐛𝐢𝐜𝐲𝐜𝐥𝐨[𝟏.𝟏.𝟎]𝐛𝐮𝐭𝐚𝐧𝐞𝐬 𝐰𝐢𝐭𝐡 𝐍,𝐍′-𝐜𝐲𝐜𝐥𝐢𝐜 𝐚𝐳𝐨𝐦𝐞𝐭𝐡𝐢𝐧𝐞 𝐢𝐦𝐢𝐧𝐞𝐬 by Zijun Zhou 𝘦𝘵 𝘢𝘭. Rhodium-catalyzed cycloaddition yields azabicyclo[3.1.1]heptanes (up to 98%, 27 examples) with broad scope; enantioselective version achieves 91% ee. 🔗 doi.org/10.1039/D5QO01147G

👉Don't miss the outside back cover article of issue 20: 𝐒𝐢𝐭𝐞 𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐇𝐞𝐜𝐤 𝐚𝐫𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐍-𝐯𝐢𝐧𝐲𝐥-𝟕-𝐚𝐳𝐚𝐢𝐧𝐝𝐨𝐥𝐞 𝐞𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐞𝐝 𝐛𝐲 𝐍-𝐨𝐱𝐢𝐝𝐞 𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧: 𝐬𝐜𝐨𝐩𝐞 𝐚𝐧𝐝 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐬𝐭𝐮𝐝𝐢𝐞𝐬 by Parthasarathi Das 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO00976F

📢 Issue 20 of OCF is now available! Read the outside front cover article 𝐁𝐲𝐩𝐚𝐬𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐚𝐛𝐧𝐨𝐫𝐦𝐚𝐥 𝐂𝐡𝐢𝐜𝐡𝐢𝐛𝐚𝐛𝐢𝐧 𝐫𝐞𝐚𝐜𝐭𝐢𝐨𝐧 𝐝𝐞𝐚𝐝-𝐞𝐧𝐝 𝐩𝐫𝐨𝐯𝐢𝐝𝐞𝐬 𝐚 𝐛𝐢𝐨𝐦𝐢𝐦𝐞𝐭𝐢𝐜 𝐚𝐜𝐜𝐞𝐬𝐬 𝐭𝐨 𝐩𝐫𝐞-𝐡𝐚𝐨𝐮𝐚𝐦𝐢𝐧𝐞 by Mehdi A. Beniddir, Erwan Poupon 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO01111F

👉𝐂𝐡𝐞𝐦𝐢𝐬𝐭𝐫𝐲 𝐍𝐨𝐛𝐞𝐥 𝐏𝐫𝐢𝐳𝐞 𝐂𝐨𝐥𝐥𝐞𝐜𝐭𝐢𝐨𝐧 𝟐𝟎𝟐𝟓 🎉A RSC cross-journal collection celebrating the 2025 Nobel Prize in Chemistry, highlighting the work of Susumu Kitagawa, Richard Robson, and Omar M. Yaghi on metal–organic frameworks (MOFs) is now online！ pubs.rsc.org/en/journals/...

We have published a outside back over article, read 𝐄𝐥𝐞𝐜𝐭𝐫𝐨𝐩𝐡𝐢𝐥𝐢𝐜 𝐢𝐧𝐬𝐞𝐫𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐫𝐢𝐧𝐠 𝐠𝐫𝐨𝐰𝐭𝐡 𝐢𝐧 𝟏,𝟐,𝟓-𝐚𝐳𝐚𝐝𝐢𝐛𝐨𝐫𝐨𝐥𝐢𝐝𝐢𝐧𝐞𝐬: 𝐭𝐡𝐞𝐨𝐫𝐞𝐭𝐢𝐜𝐚𝐥 𝐞𝐯𝐢𝐝𝐞𝐧𝐜𝐞 𝐟𝐨𝐫 𝐛𝐨𝐫𝐨𝐧-𝐝𝐫𝐢𝐯𝐞𝐧 𝐞𝐱𝐩𝐚𝐧𝐬𝐢𝐨𝐧 by J. Oscar C. Jiménez-Halla 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO...

Don't miss the inside front cover article of issue 19 𝐂𝐨𝐨𝐩𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐍-𝐡𝐞𝐭𝐞𝐫𝐨𝐜𝐲𝐜𝐥𝐢𝐜 𝐜𝐚𝐫𝐛𝐞𝐧𝐞/𝐩𝐡𝐨𝐭𝐨𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐢𝐬: 𝐯𝐢𝐬𝐢𝐛𝐥𝐞-𝐥𝐢𝐠𝐡𝐭-𝐩𝐫𝐨𝐦𝐨𝐭𝐞𝐝 𝐭𝐚𝐧𝐝𝐞𝐦 α-𝐬𝐩³ 𝐂–𝐇 𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐫𝐞𝐝𝐮𝐜𝐭𝐢𝐯𝐞 𝐍-𝐚𝐥𝐤𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐭𝐞𝐭𝐫𝐚𝐡𝐲𝐝𝐫𝐨𝐢𝐬𝐨𝐪𝐮𝐢𝐧𝐨𝐥𝐢𝐧𝐞 by C. Uma Maheswari 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO...

📢 Issue 19 of Organic Chemistry Frontiers is available! In this issue read the outside front cover article: 𝐓𝐮𝐧𝐚𝐛𝐥𝐞 𝐭𝐡𝐢𝐨𝐟𝐮𝐦𝐚𝐫𝐚𝐭𝐞 𝐬𝐭𝐞𝐫𝐞𝐨𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐜𝐲𝐜𝐥𝐨𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧𝐬 𝐯𝐢𝐚 𝐚𝐦𝐢𝐧𝐨𝐦𝐞𝐟𝐥𝐨𝐪𝐮𝐢𝐧𝐞 𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐢𝐬 by Rafał Szabla, Rafał Kowalczyk 𝘦𝘵 𝘢𝘭. 🔗 doi.org/10.1039/D5QO...

Rhodium-catalyzed hydroselenation of unsymmetric 1,3-dienes with 3,4-Markovnikov regioselectivity by Xuebin Huang et al. ⚗️ Mild, atom-economical route to selective 3,4-Markovnikov products. doi.org/10.1039/D5QO... #Catalysis #Organoselenium #Regioselectivity

🧪 Rhodium-catalyzed hydroselenation of unsymmetric 1,3-dienes by Xiao-Hui Yang et al. — Rh catalysis gives 3,4-Markovnikov products with high regioselectivity. doi.org/10.1039/D5QO... #Organoselenium #RhodiumCatalysis #Regioselectivity

Bypassing the abnormal Chichibabin reaction dead-end provides a biomimetic access to pre-haouamine by Mehdi A. Beniddir et al. 🔹 Biomimetic strategy avoids Chichibabin dead-end, enabling concise synthesis of pre-haouamine. 🌊 doi.org/10.1039/D5QO... #OrganicSynthesis #BiomimeticChemistry #Alkaloids

Harnessing the synergistic power of light and electricity: an emerging frontier in catalytic heterocycle synthesis by Huang et al. ⚡🌞 Photoelectrocatalysis enables novel pathways for heterocycle formation. 🔗 doi.org/10.1039/D5QO... #Photoelectrocatalysis #OrganicSynthesis #Heterocycles

🔥Hot article: Diastereoselective and enantioselective construction of 1,4-nonadjacent alkyne-tethered products through CuI-promoted deprotonation and addition of terminal alkynes by Ying-Chun Chen et al. ⚗️ doi.org/10.1039/D5QO... #AsymmetricCatalysis #OrganicChemistry #Alkyne

🔔Open Access: Structurally divergent reactivity of 2,2-disubstituted azetidines by Alan C. Spivey et al. 🧪 Conditions tune azetidines to N-acylation or ring expansion → diverse heterocycles for drug discovery. 🔗 doi.org/10.1039/D5QO... #Azetidines #Heterocycles #DrugDiscovery

🔥Recent advances in C(sp³)–H functionalization via molecular electrocatalysis ⚡🔬 by Peng Xiong et al. Review highlights transition-metal & metal-free systems, mechanisms & photoelectrocatalysis. doi.org/10.1039/D5QO... #OrganicChemistry #Electrocatalysis #SustainableSynthesis

Share your latest research at the Organic chemistry poster symposium 2025. Poster abstract submissions close soon – this is your last chance as an early career researcher to gain experience and get feedback at an event dedicated to you. Submit your abstract today: https://rsc.li/41IZufF #ChemSky

Electrophilic insertion and ring growth in 1,2,5-azadiborolidines: theoretical evidence for boron-driven expansion by Albert Poater et al. CO insertion enables new boracycles ⚗️ doi.org/10.1039/D5QO... #BoronChemistry #RingExpansion #ComputationalChemistry