Results of the FINEARTS-HF randomized clinical trial demonstrate that the PREDICT-HFpEF models performed well in terms of calibration and discrimination. Baseline risk did not modify the benefit of finerenone. jamanetwork.com/journals/jam...

There was no association between liberal fasting policies and witnessed aspiration. Further study of more liberal fasting policies is unlikely to find an association www.sciencedirect.com/science/arti...

Results of this cohort study suggest that the prevalence of CMP-PLP variants was substantial in patients with early-onset AF. Patients with AF carrying a CMP-PLP variant had an associated increased risk of future CMP/HF, independent of clinical and polygenic risk. jamanetwork.com/journals/jam...

Among persons with both chronic kidney disease and type 2 diabetes, initial therapy with finerenone plus empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either treatment alone. www.nejm.org/doi/full/10....

High PCATRCA was independently associated with PoCE after PCI using current-generation DES. Combining PCATRCA with traditional cardiovascular risk factors and cCTA findings may enhance risk assessment for PoCE after PCI. eurointervention.pcronline.com/article/impa...

ATTR-specific treatment and AVR both result in significant survival benefit in dual pathology AS and ATTR-CA. Results should be interpreted in the context of the non-randomized study setting and differences in patient characteristics. academic.oup.com/eurheartj/ad...

Among older adults with high-risk or intermediate-risk PE, patients treated with CBT experienced lower mortality over the follow-up of up to 3 years, but higher risk of in-hospital bleeding complications www.jacc.org/doi/10.1016/...

In stable patients with extensive noncalcified plaque volume at baseline, 18 months of evolocumab treatment was associated with a shift toward a lower risk quantitative plaque phenotype and reduction in microcalcification activity www.jacc.org/doi/10.1016/...

A significant burden of elevated Lp(a) was found in China, highlighting the necessity of prioritized Lp(a) screening in high-risk groups. Elevated Lp(a) was identified as a significant risk factor for site-specific subclinical atherosclerosis www.jacc.org/doi/10.1016/...

n this prespecified analysis of a randomized clinical trial, patients with HFimpEF remained at high risk of CV events, underscoring the need for continued management despite LVEF improvement. jamanetwork.com/journals/jam...

Deferred stenting did not reduce all-cause mortality or the composite primary outcome after 10 years but reduced hospitalization for heart failure compared with conventional PCI. www.ahajournals.org/doi/full/10....

In ACS patients treated with DCS, a 1-month prasugrel-based DAPT strategy followed by prasugrel 5 mg monotherapy reduced NACE by 49%, mainly driven by a 77% reduction of bleeding events without compromising ischaemic safety eurointervention.pcronline.com/article/one-...

The RV/LV diameter ratio offers real-time risk stratification and is a predictor of low cardiac index in patients with acute PE. www.sciencedirect.com/science/arti...

Results reveal that long-term QOL and chest pain outcomes were the same with CT- vs ICA- guided first-test strategies at 3.5 years jamanetwork.com/journals/jam...

In stable patients with extensive noncalcified plaque volume at baseline, 18 months of evolocumab treatment was associated with a shift toward a lower risk quantitative plaque phenotype and reduction in microcalcification activity www.jacc.org/doi/10.1016/...

However, post-TAVR patients required greater fluoroscopic time (21.9 vs 17.7 mins, p<0.001) and had higher rates of post-procedural stroke (0.8% vs 0.4%, p=0.02) and bleeding (5.1% vs 2.9%, p<0.001). www.ajconline.org/article/S000...

Contrast-derived indices have high specificity and negative predictive value, enabling rapid exclusion of microvascular dysfunction. This method is feasible, clinically useful and cost-saving compared with routine adenosine testing. www.ahajournals.org/doi/10.1161/...

Among patients with recent NSTEMI, a high baseline hsCRP level was associated with the presence of pan-coronary atherosclerosis and focal high-risk plaques www.jacc.org/doi/10.1016/...

Among statin-treated patients undergoing PCI, residual inflammation but not cholesterol risk was associated with an increased risk of MACE during follow-up. academic.oup.com/eurheartj/ad...

Exemplary effort by University Hospitals and Harrington Heart and Vascular Institute in Cleveland Ohio to reduce CV Mortality in a Rural Community in Ohio www.beckershospitalreview.com/cardiology/i...

In patients with nonobstructive HCM, there was a reduction in myocardial T1 time with eplerenone, consistent with a reduction in diffuse myocardial fibrosis. www.jacc.org/doi/10.1016/...

Interventional cardiologists experience significant stress, as measured by the LF/HF ratio, during complex, emergency, and complicated procedures; however, stress levels decrease later in the IC fellowship. www.doximity.com/newsfeed/c82...

Independent of the timing of statin initiation (i.e., whether for primary vs. secondary prevention of CVD), this study found an all-cause mortality benefit with statin therapy in patients on dialysis who had a very high risk for CVD or established CVD www.acc.org/Latest-in-Ca...

Non-LAD CTO PCI significantly improved LVEF (8.2%) in HFrEF patients over two years, regardless of pre-procedure viability testing or post-procedural medical therapy. www.doximity.com/newsfeed/186...

Individuals who are genetically predisposed to developing CAD also face an increased risk of developing dementia in old age. This risk is reduced in those demonstrating healthy lifestyle profiles earlier in the lifespan www.ahajournals.org/doi/full/10....