CoSy.Bio
@cosybio-uhh.bsky.social
π€ 24
π₯ 1
π 21
Computational Systems Biomedicine research group at the University Hamburg
We present FedscGen, a federated,
#PrivacyPreserving
method (built on scGen) batch-effect correction tool to help analyze distributed
#scRNAseq
datasets.
genomebiology.biomedcentral.com/articles/10....
about 1 month ago
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β¨ Congratulations to Faren, the winner of the Young Investigator Award
#RExPO25
! This is a truly well-deserved recognition of her outstanding research and impact. π
@repo4eu.bsky.social
about 2 months ago
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#Acne
and other
#SkinDisorders
are often linked to the sebaceous gland (SG). We provide a detailed molecular map of the human SG, revealing dynamic differentiation of sebocytes and identifying new
#GeneMarkers
, providing a valuable reference for future research.
www.jidonline.org/article/S002...
about 2 months ago
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ππ¦ Exciting discussions at the
@microb-ai-ome.bsky.social
Steering Committee Meeting in Vienna! Great to see progress at the intersection of
#MicrobiomeResearch
and
#AI
!
2 months ago
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Studying
#BoneTissue
proteins can be likened to finding a needle in a haystack of collagen. Our new protocol eliminates collagen interference without the use of enzymes, yielding 68% more proteins identified.
#proteomics
pubs.acs.org/doi/10.1021/...
2 months ago
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We introduce DRaCOoN π: a Python package and web tool designed for pathway-level
#DifferentialCoexpression
analysis. It features a unique benchmarking framework and demonstrates robust performance across various
#Transcriptomics
datasets.
bmcbioinformatics.biomedcentral.com/articles/10....
2 months ago
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Presenting DIGGER 2.0: we extended our
#AlternativeSplicing
software DIGGER with new functionalities, including support of the mouse interactome and NEASE for
#EnrichmentAnalysis
! Check it out here:
exbio.wzw.tum.de/digger/
3 months ago
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When is "good enough" actually good enough for
#PrognosticModels
? Our commentary tackles this question with a structured analysis of 16 scenarios + practical approaches for development decisions for healthcare-related prognostic models.
www.jmir.org/2025/1/e69341
3 months ago
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Defective interfering particles (DIPs) as potential novel
#Antivirals
! Our meta-analysis of 20
#Influenza
datasets provides insights for selecting candidates for antiviral treatment design.
academic.oup.com/nargab/artic...
4 months ago
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We compared various models predicting changes in
#KneePain
of
#Osteoarthritis
patients due to participation in supervised education and exercise and propose a concise 6-variable model for personalized prediction.
rehab.jmir.org/2025/1/e60162
4 months ago
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Introducing DREAMER, a groundbreaking tool that identifies mechanisms of
#AdverseDrugReactions
(ADRs) by linking drug and disease phenotypes to protein interaction networks. Here, DREAMER revealed
#MolecularMechanisms
behind 67 ADRs.
www.sciencedirect.com/science/arti...
5 months ago
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Join CoSy.Bio in Hamburg! We are looking for a System Administrator to support our team. π§ Linux/macOS | HPC | Automation | Bioinformatics π Hamburg ποΈ Apply by June 27 π
www.stepstone.de/stellenangeb...
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https://www.stepstone.de/stellenangebote--Systemadministration-Computational-Systems-Biology-Hamburg-Universitaet-Hamburg--12623556-inline.html?rltr=4_4_25_crl_m_0_0_0_0_0_0
5 months ago
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We wrapped up a productive
@daibetes.bsky.social
Steering Committee Meeting last week in Boston! Great discussions on how privacy-preserving
#AI
can advance
#DiabetesResearch
and
#PersonalizedPatientCare
.
5 months ago
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Soluble guanylate cyclase (sGC) protects cells from
#OxidativeStress
. Our research shows ta cGMP-dependent reduction of
#ReactiveOxygenSpecies
(ROS) upon soluble guanylate cyclase activation via a downregulation of NOX4/5 via NF-ΞΊB. Our findings have significant implications for
#StrokeRecovery
!
6 months ago
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Watch the new video on dAIbetes! This
@horizoneu.bsky.social
project leverages
#AI
and
#FederatedLearning
to transform type 2 diabetes treatment. Discover how virtual twins and secure data sharing are enabling personalized care.
#DigitalHealth
#DiabetesResearch
daibetes.eu/news/details...
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dAIbetes video - dAIbetes
dAIbetes as a whole, just have a look at the β video
https://daibetes.eu/news/details/dAIbetes_video
6 months ago
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Say goodbye to endless PDF scrolling and hello to faster discoveries! ππ Check out how DrugRepoChatter is revolutionizing
#DrugRepurposing
research!
add a skeleton here at some point
8 months ago
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Are you ready to shape the future of
#LifeSciences
? Join us and be part of the revolution in
#AI
and
#MachineLearning
innovation! Apply now!
#PhD
#postdoc
9 months ago
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π¨Join us in pioneering the future of
#LifeSciences
! Apply now to be at the forefront of
#AI
and
#MachineLearning
innovation!
9 months ago
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Meet BioChatter! CoSy.Bio contributed to this open source framework for interfacing with
#LLMs
in biomedical research while ensuring user safety and privacy. Explore BioChatter at
www.nature.com/articles/s41...
@saezlab.bsky.social
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A platform for the biomedical application of large language models - Nature Biotechnology
Nature Biotechnology - A platform for the biomedical application of large language models
https://www.nature.com/articles/s41587-024-02534-3
9 months ago
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Predicting drug responses is crucial for
#PersonalizedMedicine
. Our study reveals that
#TranscriptionFactor
activity-based methods outperform others in this task .
#MachineLearning
www.nature.com/articles/s41...
10 months ago
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