loading . . . Unit 4 â Biological Database Management (804) (IMSC BIOINFORMATICS) Full Notes This module introduces the core concepts of sequence alignment and its central role in bioinformatics. You will learn how DNA, RNA, and protein sequences are compared to identify similarities, conserved regions, and evolutionary relationships. The content explores different types of alignments, scoring matrices such as PAM and BLOSUM, and widely used tools like BLAST and FASTA. It also covers advanced algorithms including SmithâWaterman and PSI-BLAST, along with concepts like PSSM, helping you understand how sequence analysis supports functional prediction, evolutionary studies, and modern biological research. https://www.rathbiotaclan.com/sequence-alignment-blast-fasta-pam-blosum-guide/?utm_source=bluesky&utm_medium=jetpack_social