The November 2025 edition of This Month in T1D Research is out youtu.be/IuWCsUcggHM We look at: - A new marker for T1D progression - A possible link between the gut microbiome and T1D - Maternal protection from T1D in the womb - Hydrogel protection for transplanted cells

With a recent update of the CamAPS software, there is a tiny green '9.2' in the widget icons which changes as my BGLs change (the large 9.2 at the bottom of the screen is thanks to xDrip+). Even without clever hackery with xDrip+ I can now see my BGLs on the lock screen :)

Something which seems to be across chronic diseases and politics is "Rage-Grifting". Basically, the monetising of Rage-bait. There is money to be made in making up conspiracies and playing to people's feelings of impotent rage, than there is in being part of the solution.

Interesting new study looking at close to 200,000 US adults over 30 years to see how a low carb diet affects the risk of type 2 diabetes. The conclusion was it is protective only if it uses plant-based protein, healthy fats, and high quality carbs. pmc.ncbi.nlm.nih.gov/articles/PMC...

Insulin pump refill while at the airport gate

Alas, not even middle-aged white privilege got me through this time. Domestic flight from Sydney to Canberra. Requested a path down and the security person refused insisting the new machines are safe for insulin pumps. Diabetes Australia, let's sort this out.

At the Diabetes Australia Kellion Victory Awards celebrating those who have lived with diabetes for 50 or more years. Always inspirational and always emotional.

Think insulin resistance is a type 2 thing? It isn't. Type 1s are also insulin resistant, relative to non-diabetics. Previous studies suggest the cause is insulin running around the body, compared to non-diabetics where most of it gets cleared by the liver.

The multistage chart for type 1 diabetes. Please note that if you only test positive for 1 autoantibody you are unlikely to progress to later stage type 1. There is a lot of misinformation on social media about this aspect.

I might have published this before but these are the phases for drug development which goes some of the way of explaining the cost and time it takes to get medications to market, for the sake of safety and efficacy.

At the official launch of ACT-T1D, researchers looking at medications beyond insulin (adjunct therapies)

The T1D stats for Australia

The T1D stats for Australia

Just been watching a couple of clinicians talk about their experiences in the US with inhaled insulin. Super quick, no need for meal pre-bolus. Also may be useful on exercise days for T1D as an alternative to AID/MDI to minimise insulin on board (TI = Inhaled Insulin)

I've resurrected This Month in Type 1 Research. For the October 2025 edition go to youtu.be/UE51E_9OoEM #ThisMonthInType1DiabetesResearch

I'm quite the fan of vaccines and, if you're not, good luck with that.

Interesting presentation on allergies. Introducing egg and peanut in the diet of babies, who have a genetic predisposition to allergy, as they start solids, led to a significant reduction in allergy development (cohort 1 = no intro, cohort 2 = intro).

An example of cherry-picking correlations to come to an erroneous conclusion. Since the 80s obesity rates have doubled while heart disease deaths have halved...

The 4 Big Levers of Diabetes and people pulling different ones for success macintyrehealth.com.au/the-four-big... featuring @bionicwookiee.bsky.social , Michael Fitzpatrick, and the late Dr Bernstein.

A new journey begins. See how it goes preserving the few remaining beta cells ;)

My HbA1c journey since LADA diagnosis. Initially 9.6% I went super-strict and the HbA1c went down to 5.3% and led to mild EWDR (your eyes don't like big HbA1c drops). The bump at 2022 was the end of my insulin-free honeymoon. I'm now at 5.4% i.e. back to the HbA1c post-diagnosis

All finished with the endo and couldn't be happier. Access to a literal professor of endocrinology, spending about an hour with him (first consult) including a foot check. Scripts refilled and another appt in 6 months. All for the total price of $0 #MedicareRocks

Travelling to my endo by boat.

A couple of shots of my shenanigans at #ADATS25 last week :) www.youtube.com/watch?v=VCrd...

That is a wrap from #25ADC and #ADATS25 A final debrief with some #dedoc alumni (David Burren, @moodwife.bsky.social , and @t1bionic.bsky.social ) Again thank you NADCaustralia and DiabetesAus for enabling me to attend and being a #DAPeoplesVoice

AID is the preferred standard of care. Let's get pumps federally funded so ALL people with type 1 have access to this lifesaving technology. #25ADC #DAPeoplesVoice

Health care professionals: Learn from the users. They are often very friendly and keen to share what works for them. #25ADC #DAPeoplesVoice

The history of Australian d-tech #25ADC #DAPeoplesVoice

An interesting find. Long term intensive insulin therapy may improve glucose control but generally leads to weight gain which counters the long term heart health benefits #25ADC #DAPeoplesVoice

Current state of beta cell transplants. We can achieve insulin independence with immune suppression but without it is still elusive. #25ADC #DAPeoplesVoice

A vision for a 'cure' (normoglycaemia) in the future #ADC2025 #DAPeoplesVoice

Preliminary research suggests whey protein, 30 minutes before moderate exercise can be useful in T1D exercise. Call out to Dessi Zaharieva who was involved in most of the studies presented on stage #25ADC #DAPeoplesVoice

Protein stimulated the liver's production of glucose and the quicker the protein absorption, the stronger the response. I have now seen a couple of studies using this to counter overnight hypos and for exercise. #25ADC #DAPeoplesVoice

Tirzepatide (Mounjaro) shown as beneficial for T1Ds including a reduction of insulin need, outside of weight loss, for reasons not yet fully understood. #25ADC #DAPeoplesVoice

Case study of using DPP4i's and SGLT2i's for LADA in an 18 year old. AGP shows strong response in terms of glucose variability #25ADC #DAPeoplesVoice

Showing you can get T1D at any age, a case of an 83 year old with positive autoantibody T1D is presented #25ADC #DAPeoplesVoice

Low carb is on the radar of research but this review of available data found limited reliable evidence, contrary to reports from lived experience. #25ADC #DAPeoplesVoice

Interesting poster looking at how fully closed loop compares to hybrid closed loop for different carb intakes. Short version is it compares well, authors including @bionicwookiee.bsky.social #25ADC #DAPeoplesVoice #TryNotDeclaringOneMealOnAID

Another surprising result. No study has shown you can prevent type 2 diabetes in a community context. #25ADC #DAPeoplesVoice

A really interesting result. Various studies show intensive lifestyle interventions with type 2 diabetes, doesn't improve heart health or all-cause mortality rates. Even when the intervention leads to remission. #25ADC #DAPeoplesVoice

Bad Word Bingo at #25ADC. This is the second time I've seen the word 'adherence' used in a stage presentation. #DAPeoplesVoice

High dose blood pressure medication can lower blood pressure but multiple low dose is more effective and less likely to show side effects. #25ADC #DAPeoplesVoice

Levels of blood pressure reduction one can expect from 'lifestyle interventions' #25ADC #DAPeoplesVoice

Blood Pressure targets. Including some for people with diabetes #25ADC #DAPeoplesVoice

I missed the slide but @Prof_AJ_Jenkins advocates for prescription fish oils rather than pharmacy ones because of oxidised oil levels which are unhealthy for the heart. #25ADC #DAPeoplesVoice

@Prof_AJ_Jenkins shows some of the international guides for LDLs #25ADC #DAPeoplesVoice

@Prof_AJ_Jenkins advocates for quite aggressive LDL targets and posits while lifestyle adjustments are important, medication is still necessary to achieve these targets. #25ADC #DAPeoplesVoice

@Prof_AJ_Jenkins advocates the lowest possible LDL levels over the longest possible time based on population and clinical studies. #25ADC #DAPeoplesVoice

@Prof_AJ_Jenkins speaking on lipids in diabetes. Arguably one of the world experts on the subject (and a collaborator of mine at the Baker Heart and Diabetes Institute. Looking forward to the talk #25ADC #DAPeoplesVoice